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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
|
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Deletion
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OCR02-4
(D)
,
OCR02-11
(D)
,
DE(ilvE-ilvC)2049
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
ilvY
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Related strains
|
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Strains Search
|
Search strains by gene name:
ilvY
Search strains by all related name:
ilvY b3773 ECK3765 f297 JW3746
|
General information (Go to Linear View: )
|
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Gene Name
|
ilvY
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Alternative name
|
b3773,ECK3765,f297,JW3746
|
|
Location, Length
|
3,954,950 - 3,955,843
(
-
)
;
85.24
min
;
894
(bp) ,
297
(aa)
|
|
Product
|
DNA-binding transcriptional dual regulator
|
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Operon Name
|
ilvY
|
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Note
|
positive regulator for ilvC; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0006350 - transcription
|
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Function
|
regulator; Amino acid biosynthesis: Isoleucine, Valine
|
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Gene Ontology
|
GO:0003677
;
DNA binding ( ilvY )
GO:0003700
;
transcription factor activity ( ilvY )
GO:0005737
;
cytoplasm ( ilvY )
GO:0006350
;
transcription ( ilvY )
GO:0006355
;
regulation of transcription, DNA-dependent ( ilvY )
GO:0008652
;
amino acid biosynthetic process ( ilvY )
GO:0009082
;
branched chain family amino acid biosynthetic process ( ilvY )
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PID
|
1790208
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
ILVY_ECOLI
(
P05827
)
|
|
- Protein name
|
HTH-type transcriptional regulator ilvY.
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- Synonyms
|
|
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- Gene name
|
Name=ilvY; OrderedLocusNames=b3773;
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Homology Analysis
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BLAST
|
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Bacteria
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GTOP
|
ilvY
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
Chain A, Dntr From Burkholderia Sp. Strain Dnt In Complex With Thiocyanate
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
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BLAST
|
HTH-type transcriptional regulator ilvY
|
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PSI-BLAST
|
HTH-type transcriptional regulator ilvY
|
|
nr
(database updated :
2007.02.20
)
|
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BLAST
|
DNA-binding transcriptional dual regulator [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
HTH_LYSR_FAMILY
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MMBR References
|
J Bacteriol. 1981;146(2):718-24.
Mutations in the ilvY gene of Escherichia coli K-12 that cause constitutive expression of ilvC.
Biel AJ, Umbarger HE.
(
6783625
)
|
J Biol Chem. 1989;264:1224-1231
Overlapping transcription and termination of the convergent ilvA and ilvY genes of Escherichia coli.
Sameshima, J. H., R. C. Wek, and G. W. Hatfield.
|
J Biol Chem. 1986;261:2441-2450
Nucleotide sequence and in vivo expression of the ilvY and ilvC genes in Escherichia coli K12. Transcription from divergent overlapping promoters.
Wek, R. C., and G. W. Hatfield.
|
J Mol Biol. 1988;200(3):427-38.
Generation of a detailed physical and genetic map of the ilv-metE-udp region of the Escherichia coli chromosome.
Aldea M, Maples VF, Kushner SR.
(
3294419
)
|
Science. 1992;257(5071):771-8.
Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.
Daniels DL, Plunkett G 3rd, Burland VD, Blattner FR.
(
1379743
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MDLRDLKTFL HLAESRHFGR SARAMHVSPS TLSRQIQRLE EDLGQPLFVR DNRTVTLTEA GEELRVFAQQ
0071 TLLQYQQLRH TIDQQGPSLS GELHIFCSVT AAYSHLPPIL DRFRAEHPSV EIKLTTGDAA DAMEKVVTGE
0141 ADLAIAGKPE TLPGAVAFSM LENLAVVLIA PALPCPVRNQ VSVEKPDWST VPFIMADQGP VRRRIELWFR
0211 RNKISNPMIY ATVGGHEAMV SMVALGCGVA LLPEVVLENS PEPVRNRVMI LERSDEKTPF ELGVCAQKKR
0281 LHEPLIEAFW KILPNHK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 agattgaatt cactatatga caggaaattt
-070 attgcggaaa ttgatatatt cacaacgtca cattgcaatt tttgcaacgt caacatcgag ggctgtccct
0001 gtggatttac gcgatctgaa aaccttcctg catctggcgg aaagccgcca ttttggccgc agcgcgcggg
0071 cgatgcacgt tagcccatcc acgctctcac ggcagattca gcgcctggaa gaagatctcg gtcagccgct
0141 gtttgtgcgc gataaccgca cggtgacgct gactgaagcg ggcgaagagc tgcgcgtttt cgcccagcaa
0211 acgctgttgc agtatcagca gttgcgccac accatcgatc agcaagggcc gtcgctctct ggcgaattac
0281 atatcttctg ctcggtgacc gctgcctaca gccatctgcc gccgattctg gatcgcttcc gcgcggaaca
0351 cccgtcggtg gagattaaac ttactactgg tgatgcggca gatgcgatgg aaaaggtggt cactggtgaa
0421 gcggatctgg cgattgcggg taaaccggaa accttgcccg gcgcagtggc gttttcgatg ctggagaatc
0491 tggcagtagt gctgattgcc cccgcgctgc cctgcccggt gcgtaatcag gtgtcggtag agaagccgga
0561 ctggtcaacg gtgccgttta ttatggccga tcaggggccg gtacgccgcc gcattgaact gtggtttcga
0631 cgcaataaaa tcagtaaccc gatgatttac gccacggttg gcgggcatga agcgatggta tcgatggtgg
0701 cactcggctg tggcgtggca ttgttgccgg aagtggtgct ggaaaacagc cccgaaccgg tgcgtaaccg
0771 cgtgatgatt ttagagcgca gcgatgagaa aacgccgttt gagctgggcg tgtgtgcgca gaaaaagcgg
0841 ctacatgagc cgctaattga ggcattctgg aagattttgc cgaaccacaa atgacgttgt cgcgcgggta
0911 ggcctgataa gcgaagcgct atcaggcatt tttccctaac ccgccaaaaa gaacctgaac gccgggttat
0981 tggtttcgtc gtgg
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