|
PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
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|
References (PMID)
|
Mol Microbiol. 1991;5(6):1375-83.
A chimeric nucleotide-binding protein, encoded by a hisP-malK hybrid gene, is functional in maltose transport in Salmonella typhimurium.
Schneider E, Walter C.
(
1787792
)
|
|
|
Deletion
|
OCL64
(D)
,
OCL64-3
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
hisM
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
hisM
Search strains by all related name:
hisM b2307 ECK2301 f238 JW2304
|
General information (Go to Linear View: )
|
|
Gene Name
|
hisM
|
|
Alternative name
|
b2307,ECK2301,f238,JW2304
|
|
Location, Length
|
2,422,539 - 2,423,255
(
-
)
;
52.21
min
;
717
(bp) ,
238
(aa)
|
|
Product
|
histidine/lysine/arginine/ornithine transporter subunit
|
|
Operon Name
|
argT-hisJQMP
|
|
Note
|
histidine transport, membrane protein M; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009089 - lysine biosynthetic process via diaminopimelate; GO_process: GO:0006526 - arginine biosynthetic process
|
|
Function
|
transport; Transport of small molecules: Amino acids, amines
|
|
Gene Ontology
|
GO:0005215
;
transporter activity ( hisM )
GO:0005886
;
plasma membrane ( hisM )
GO:0006810
;
transport ( hisM )
GO:0006865
;
amino acid transport ( hisM )
GO:0009276
;
1-2nm peptidoglycan-based cell wall ( hisM )
GO:0016020
;
membrane ( hisM )
GO:0016021
;
integral to membrane ( hisM )
|
|
PID
|
1788645
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
HISM_ECOLI
(
P20091
;
P76936
)
|
|
- Protein name
|
Histidine transport system permease protein hisM.
|
|
- Synonyms
|
|
|
- Gene name
|
OrderedLocusNames=b2307, c2849, z3569, ECs3191, SF2383, S2518;
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Homology Analysis
|
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BLAST
|
|
Bacteria
|
|
GTOP
|
hisM
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Histidine transport system permease protein hisM
|
|
PSI-BLAST
|
Histidine transport system permease protein hisM
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
histidine transport system membrane protein M [Escherichia coli O157:H7 str. Sakai]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
BPD_TRANSP_INN_MEMBR
|
|
MMBR References
|
Nucleic Acids Res. 1987;15(20):8568
Sequence of the complete P protein gene and part of the M protein gene from the histidine transport operon of Escherichia coli compared to that of Salmonella typhimurium.
Kraft R, Leinwand LA.
(
3313284
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MIEILHEYWK PLLWTDGYRF TGVAITLWLL ILSVVIGGVL ALFLAIGRVS SNKYIQFPIW LFTYIFRGTP
0071 LYVQLLVFYS GMYTLEIVKG TEFLNAFFRS GLNCTVLALT LNTCAYTTEI FAGAIRSVPH GEIEAARAYG
0141 FSTFKMYRCI ILPSALRIAL PAYSNEVILM LHSTALAFTA TVPDLLKIAR DINAATYQPF TAFGIAAVLY
0211 LIISYVLISL FRRAEKRWLQ HVKPSSTH
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tcgtctgtgg cgtgatttac ctggttttca
-070 ccactgtttc caatggtgtg ctgctgttcc ttgagcgccg ctactccgtg ggtgtgaaga gggctgacct
0001 gtgatcgaaa tcttacatga atactggaaa ccgctgctgt ggaccgacgg ttatcgcttt actggtgtgg
0071 cgatcactct gtggctgctt attttgtcgg tagtgatagg cggagtcctg gcgctgtttc tggcgattgg
0141 tcgtgtctcc agtaataaat acatccagtt tccaatctgg ttatttacct atatttttcg cggtacgccg
0211 ctgtatgttc agttgctggt gttctattcc ggcatgtaca cgcttgagat tgttaaggga accgaattcc
0281 ttaacgcttt cttccgcagt ggcctgaact gtaccgtgct ggcgctgacg cttaacacct gcgcttacac
0351 taccgagatt tttgctgggg caatccgttc ggttccgcat ggggaaattg aagccgccag agcctatggc
0421 ttctcgactt ttaaaatgta tcgctgcatt attttgcctt ctgcgctgcg tattgcgtta ccggcataca
0491 gcaacgaagt gatcctgatg ctgcactcta ctgcgttggc atttactgcc acggtgccgg atctgctgaa
0561 aatagcccgc gatattaacg ccgccacgta tcaacctttt accgccttcg gcattgccgc ggtgctctat
0631 ttaatcatct cttatgtcct gatcagcctc tttcgcagag cggaaaaacg ctggttgcag catgtgaaac
0701 cttcttcaac gcactgagaa tacgatgtcc gagaataaat taaacgttat cgatttgcac aaacgctacg
0771 gcgaacatga agtgctgaaa ggggtatcac tgcaagcgaa tgccgga
|
