PEC Original Annotations
|
Essentiality
|
Class
|
non-essential
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
Deletion
|
OCL61
(D)
|
Related gene (W3110 PEC)
|
Gene Search
|
Search MG1655 PEC by gene name:
xapA
|
Related strains
|
Strains Search
|
Search strains by gene name:
xapA
Search strains by all related name:
xapA b2407 ECK2401 f277 JW2398 pdnA pndA
|
General information (Go to Linear View: )
|
Gene Name
|
xapA
|
Alternative name
|
b2407,ECK2401,f277,JW2398,pdnA,pndA
|
Location, Length
|
2,522,067 - 2,522,900
(
-
)
;
54.36
min
;
834
(bp) ,
277
(aa)
|
Product
|
purine nucleoside phosphorylase II
|
Operon Name
|
xapAB
|
Note
|
xanthosine phosphorylase; GO_process: GO:0015949 - nucleobase, nucleoside and nucleotide interconversion
|
Function
|
enzyme; Central intermediary metabolism: Nucleotide interconversions
|
Gene Ontology
|
GO:0004731
;
purine-nucleoside phosphorylase activity ( xapA )
GO:0006139
;
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ( xapA )
GO:0016740
;
transferase activity ( xapA )
GO:0016757
;
transferase activity, transferring glycosyl groups ( xapA )
GO:0016763
;
transferase activity, transferring pentosyl groups ( xapA )
|
PID
|
1788746
|
EC number
(KEGG Pathway)
|
2.4.2.1
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
XAPA_ECOLI
(
P45563
;
P77325
)
|
- Protein name
|
Xanthosine phosphorylase
|
- Synonyms
|
EC 2.4.2.-
|
- Gene name
|
Name=xapA; Synonyms=pndA; OrderedLocusNames=b2407;
|
Homology Analysis
|
BLAST
|
Bacteria
|
GTOP
|
xapA
(
homologous genes of other bacterias
)
|
PDB
(database updated :
2007.02.20
)
|
PSI-BLAST
|
Chain A, Escherichia Coli Purine Nucleoside Phosphorylase Ii, The Product Of The Xapa Gene
|
SWISS-PROT
(database updated :
2007.02.20
)
|
BLAST
|
Xanthosine phosphorylase
|
PSI-BLAST
|
Xanthosine phosphorylase
|
nr
(database updated :
2007.02.20
)
|
BLAST
|
purine nucleoside phosphorylase [Escherichia coli K12]
|
Pfam 28.0
(database updated :
2015-05
)
|
Pfam
|
|
PROSITE
|
PROSITE
|
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
PNP_MTAP_2
|
MMBR References
|
J Mol Biol. 1990;214(4):825-43.
Precise mapping and comparison of two evolutionarily related regions of the Escherichia coli K-12 chromosome. Evolution of valU and lysT from an ancestral tRNA operon.
Brun YV, Breton R, Lanouette P, Lapointe J.
(
2201776
)
|
Sequences |
Amino acid
FASTA format
|
0001 MSQVQFSHNP LFCIDIIKTY KPDFTPRVAF ILGSGLGALA DQIENAVAIS YEKLPGFPVS TVHGHAGELV
0071 LGHLQGVPVV CMKGRGHFYE GRGMTIMTDA IRTFKLLGCE LLFCTNAAGS LRPEVGAGSL VALKDHINTM
0141 PGTPMVGLND DRFGERFFSL ANAYDAEYRA LLQKVAKEEG FPLTEGVFVS YPGPNFETAA EIRMMQIIGG
0211 DVVGMSVVPE VISARHCDLK VVAVSAITNM AEGLSDVKLS HAQTLAAAEL SKQNFINLIC GFLRKIA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cgaatcgcta ttgaatgcgt gagaaaagtg
-070 tattggtaag agccgggaca acctcgctat aaaaaggcgt tagattccac cctacagaaa aaggatatgt
0001 atgtctcagg ttcaattttc tcataacccg ctgttttgca tagatattat caagacttat aaacctgatt
0071 tcacgccacg agtggccttt attttaggtt ccgggctcgg cgcgctggcc gatcagattg agaacgctgt
0141 cgcaatttcc tacgaaaagc tgccgggctt cccggtaagt acggtacatg gtcatgcggg ggagttagtg
0211 ctgggccatc tccagggcgt accggtggta tgtatgaaag gtcgcggaca tttctacgaa ggtcgtggaa
0281 tgaccattat gactgacgca attcgtacct ttaagctgct gggctgcgag ctactgttct gcaccaatgc
0351 ggcaggctcg ctgcgtccgg aagtgggggc aggcagcctg gtcgcattga aagatcatat caacaccatg
0421 cccggtacgc cgatggtggg tcttaacgat gatcgttttg gagagcgctt cttctcactg gcaaatgcct
0491 acgatgcgga ataccgcgca ctgttacaaa aagtggcgaa agaagagggt ttccctctga cggagggcgt
0561 gttcgtctcg tatccggggc cgaatttcga gactgcggcg gaaattcgca tgatgcaaat tattggtggg
0631 gatgttgttg gtatgtctgt ggtgcctgag gttatttcag ctcgccattg cgaccttaaa gtcgttgcgg
0701 tctctgcgat taccaatatg gcggaaggtt taagcgatgt gaaattgtca catgcgcaaa cgctggcggc
0771 tgcggagctc tctaagcaga acttcatcaa ccttatttgt ggctttctgc gcaaaattgc ctgagaaaaa
0841 caataagaaa cggcctcgcg ggtgaggcca aatgatgcga caaggaaacg attatgagca tcgcgatgcg
0911 cttaaaggta atgtcctttt tgca
|