PEC Original Annotations
|
Essentiality
|
Class
|
essential
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
Deletion
|
OCR12
(D)
|
Related gene (W3110 PEC)
|
Gene Search
|
Search MG1655 PEC by gene name:
ubiA
|
Related strains
|
Strains Search
|
Search strains by gene name:
ubiA
Search strains by all related name:
ubiA b4040 cyr ECK4032 JW4000 o290b sdgG?
|
General information (Go to Linear View:)
|
Gene Name
|
ubiA
|
Alternative name
|
b4040,cyr,ECK4032,JW4000,o290b,sdgG?
|
Location, Length
|
4,251,039 - 4,251,911
(
+
)
;
91.62
min
;
873
(bp) ,
290
(aa)
|
Product
|
p-hydroxybenzoate octaprenyltransferase
|
Operon Name
|
ubiCA
|
Note
|
4-hydroxybenzoate-octaprenyltransferase; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009060 - aerobic respiration
|
Function
|
enzyme; Biosynthesis of cofactors, carriers: Menaquinone, ubiquinone
|
Gene Ontology
|
GO:0000287
;
magnesium ion binding ( ubiA )
GO:0004659
;
prenyltransferase activity ( ubiA )
GO:0005886
;
plasma membrane ( ubiA )
GO:0006744
;
ubiquinone biosynthetic process ( ubiA )
GO:0008412
;
4-hydroxybenzoate octaprenyltransferase activity ( ubiA )
GO:0009058
;
biosynthetic process ( ubiA )
GO:0016020
;
membrane ( ubiA )
GO:0016021
;
integral to membrane ( ubiA )
GO:0016740
;
transferase activity ( ubiA )
|
PID
|
1790473
|
EC number
(KEGG Pathway)
|
2.5.1.-
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
UBIA_ECOLI
(
P26601
)
|
- Protein name
|
4-hydroxybenzoate octaprenyltransferase
|
- Synonyms
|
EC 2.5.1.-, 4-HB polyprenyltransferase
|
- Gene name
|
OrderedLocusNames=b4040, c5010, z5639, ECs5023;
|
Homology Analysis
|
BLAST
|
Bacteria
|
GTOP
|
ubiA
(
homologous genes of other bacterias
)
|
PDB
(database updated :
2007.02.20
)
|
PSI-BLAST
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
BLAST
|
4-hydroxybenzoate octaprenyltransferase (4-HB polyprenyltransferase)
|
PSI-BLAST
|
4-hydroxybenzoate octaprenyltransferase
|
nr
(database updated :
2007.02.20
)
|
BLAST
|
4-hydroxybenzoate-octaprenyl transferase [Escherichia coli]
|
Pfam 28.0
(database updated :
2015-05
)
|
Pfam
|
|
PROSITE
|
PROSITE
|
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
UBIA
|
MMBR References
|
Gene. 1993;129(1):9-16.
The 92-min region of the Escherichia coli chromosome: location and cloning of the ubiA and alr genes.
Lilley PE, Stamford NP, Vasudevan SG, Dixon NE.
(
8335265
)
|
Gene. 1980;10(3):237-47.
Isolation of recombinant plasmids and phage carrying the lexA gene of Escherichia coli K-12.
Little JW.
(
6254842
)
|
J Bacteriol. 1992;174(17):5762
Location of the ubiA gene on the physical map of Escherichia coli.
Nishimura K, Nakahigashi K, Inokuchi H.
(
1512213
)
|
FEBS Lett. 1997;414(2):327-32.
Apo structure of the ligand-binding domain of aspartate receptor from Escherichia coli and its comparison with ligand-bound or pseudoligand-bound structures.
Chi YI, Yokota H, Kim SH.
(
9315712
)
|
Sequences |
Amino acid
FASTA format
|
0001 MEWSLTQNKL LAFHRLMRTD KPIGALLLLW PTLWALWVAT PGVPQLWILA VFVAGVWLMR AAGCVVNDYA
0071 DRKFDGHVKR TANRPLPSGA VTEKEARALF VVLVLISFLL VLTLNTMTIL LSIAALALAW VYPFMKRYTH
0141 LPQVVLGAAF GWSIPMAFAA VSESVPLSCW LMFLANILWA VAYDTQYAMV DRDDDVKIGI KSTAILFGQY
0211 DKLIIGILQI GVLALMAIIG ELNGLGWGYY WSILVAGALF VYQQKLIANR EREACFKAFM NNNYVGLVLF
0281 LGLAMSYWHF
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GCTGTGGGGG CGACGTTCCC GCCTGCGATT
-070 AAGCGGTAAA CCGCTGTTGC TAACAGAACT GTTTTTACCG GCGTCACCGT TGTACTAAGA GGAAAAAAAT
0001 atggagtgga gtctgacgca gaataagctg ctggcgtttc atcgcttaat gcgtacggat aagccaattg
0071 gcgcgttact gctgctctgg ccaacattat gggcgttgtg ggtggcgaca ccgggcgttc cccagctctg
0141 gatcctggcg gtgtttgtcg cgggtgtctg gctgatgcgc gctgccggat gtgtggtgaa tgattatgct
0211 gaccgcaagt ttgatggtca tgttaagcgc acggcgaacc gaccacttcc cagcggcgcg gtaacagaga
0281 aagaggcgcg cgcgctgttt gtcgtgctgg tactgatttc gtttttactg gtgctgacgc tgaatacgat
0351 gaccattctg ttgtcgattg ccgcgctagc gctggcgtgg gtgtacccgt ttatgaagcg gtatacccat
0421 ctaccgcaag tggtgctggg cgcggcgttt ggctggtcga ttccaatggc ttttgccgct gtgagtgagt
0491 cggtgccatt gagttgctgg ttaatgttcc tcgccaatat tctctgggcg gtggcttacg acacgcagta
0561 tgcgatggtt gaccgcgatg atgatgtgaa gattggcatt aaatccacgg caatcctgtt cggccaatac
0631 gataaattga ttattggtat tttgcagatt ggcgtactgg cactgatggc gatcatcggt gagttaaatg
0701 gcttaggctg gggatattac tggtcaattc tggtggctgg cgcgctgttt gtttatcaac aaaaactgat
0771 tgccaaccgc gagcgtgaag cctgctttaa agcatttatg aataataact atgttggtct ggtactattt
0841 ttagggctgg caatgagtta ctggcatttc tgaTGATGTA AAAAAGCCGG ATGATCATCC GGCTTTCTTC
0911 TGGGTTGCCT GATGCGCGGC GCTTCTCAGG CCTACACAAC ACATCGCAAT TTATTGAATT TGC
|