|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
J Bacteriol. 1988;170(11):5360-3.
Genetic analysis of the tdcABC operon of Escherichia coli K-12.
Schweizer HP, Datta P.
(
3053660
)
|
|
|
Deletion
|
5
(LD)
,
OCL32
(D)
,
OCL32,34-1 (LD 5-1'_CRS)
(D)
,
OCL32,34-2 (LD 5-1'_P/O)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
tdcB
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
tdcB
Search strains by all related name:
tdcB b3117 ECK3106 f329 JW3088 tdc
|
General information (Go to Linear View: )
|
|
Gene Name
|
tdcB
|
|
Alternative name
|
b3117,ECK3106,f329,JW3088,tdc
|
|
Location, Length
|
3,263,061 - 3,264,050
(
-
)
;
70.33
min
;
990
(bp) ,
329
(aa)
|
|
Product
|
catabolic threonine dehydratase, PLP-dependent
|
|
Operon Name
|
tdcABCDEFG
|
|
Note
|
threonine dehydratase, catabolic; GO_process: GO:0009063 - cellular amino acid catabolic process
|
|
Function
|
enzyme; Degradation of small molecules: Amino acids
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( tdcB )
GO:0004794
;
L-threonine ammonia-lyase activity ( tdcB )
GO:0006520
;
amino acid metabolic process ( tdcB )
GO:0008152
;
metabolic process ( tdcB )
GO:0016829
;
lyase activity ( tdcB )
GO:0030170
;
pyridoxal phosphate binding ( tdcB )
|
|
PID
|
1789505
|
EC number
(KEGG Pathway)
|
4.3.1.19
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
tdcB
(
EG10990
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
THD2_ECOLI
(
P05792
)
|
|
- Protein name
|
Threonine dehydratase catabolic
|
|
- Synonyms
|
EC 4.3.1.19, Threonine deaminase
|
|
- Gene name
|
OrderedLocusNames=b3117, c3875, z4469, ECs3997, SF3157, S3369;
|
|
MMBR References
|
J Bacteriol. 1988;170(11):5352-9.
Molecular characterization of the tdc operon of Escherichia coli K-12.
Goss TJ, Schweizer HP, Datta P.
(
3053659
)
|
J Bacteriol. 1984;158(3):826-31.
Escherichia coli K-12 mutation that inactivates biodegradative threonine dehydratase by transposon Tn5 insertion.
Goss TJ, Datta P.
(
6327641
)
|
Mol Gen Genet. 1985;201(2):308-14.
Molecular cloning and expression of the biodegradative threonine dehydratase gene (tdc) of Escherichia coli K12.
Goss TJ, Datta P.
(
3003533
)
|
Nucleic Acids Res. 1989;17(10):3994
The complete nucleotide sequence of the tdc region of Escherichia coli.
Schweizer HP, Datta P.
(
2660107
)
|
Mol Gen Genet. 1991;228(1-2):125-8.
Physical linkage and transcriptional orientation of the tdc operon on the Escherichia coli chromosome.
Schweizer HP, Datta P.
(
1886605
)
|
Proc Natl Acad Sci U S A. 1987;84:393-397
Covalent structure of biodegradative threonine dehydratase of Escherichia coli: homology with other dehydratases.
Datta, P., T. J. Gross, J. R. Omnass, and R. V. Patil.
|
| Sequences |
Amino acid
FASTA format
|
0001 MHITYDLPVA IDDIIEAKQR LAGRIYKTGM PRSNYFSERC KGEIFLKFEN MQRTGSFKIR GAFNKLSSLT
0071 DAEKRKGVVA CSAGNHAQGV SLSCAMLGID GKVVMPKGAP KSKVAATCDY SAEVVLHGDN FNDTIAKVSE
0141 IVEMEGRIFI PPYDDPKVIA GQGTIGLEIM EDLYDVDNVI VPIGGGGLIA GIAVAIKSIN PTIRVIGVQS
0211 ENVHGMAASF HSGEITTHRT TGTLADGCDV SRPGNLTYEI VRELVDDIVL VSEDEIRNSM IALIQRNKVV
0281 TEGAGALACA ALLSGKLDQY IQNRKTVSII SGGNIDLSRV SQITGFVDA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 agttatttgt ttttatttaa acataaataa
-070 tccacctgtc tgtcttgcag gtgtcggtta cggttaccta catatttaat tcaggcgaag aggttttata
0001 atgcatatta catacgatct gccggttgct attgatgaca ttattgaagc gaaacaacga ctggctgggc
0071 gaatttataa aacaggcatg cctcgctcca actattttag tgaacgttgc aaaggtgaaa tattcctgaa
0141 gtttgaaaat atgcagcgta cgggttcatt taaaattcgt ggcgcattta ataaattaag ttcactgacc
0211 gatgcggaaa aacgcaaagg cgtggtggcc tgttctgcgg gcaaccatgc gcaaggggtt tccctctcct
0281 gcgcgatgct gggtatcgac ggtaaagtgg tgatgccaaa aggtgcgcca aaatccaaag tagcggcaac
0351 gtgcgactac tccgcagaag tcgttctgca tggtgataac ttcaacgaca ctatcgctaa agtgagcgaa
0421 attgtcgaaa tggaaggccg tatttttatc ccaccttacg atgatccgaa agtgattgct ggccagggaa
0491 cgattggtct ggaaattatg gaagatctct atgatgtcga taacgtgatt gtgccaattg gtggtggcgg
0561 tttaattgct ggtattgcgg tggcaattaa atctattaac ccgaccattc gtgttattgg cgtacagtct
0631 gaaaacgttc acggcatggc ggcttctttc cactccggag aaataaccac gcaccgaact accggcaccc
0701 tggcggatgg ttgtgatgtc tcccgcccgg gtaatttaac ttacgaaatc gttcgtgaat tagtcgatga
0771 catcgtgctg gtcagcgaag acgaaatcag aaacagtatg attgccttaa ttcagcgcaa taaagtcgtc
0841 accgaaggcg caggcgctct ggcatgtgct gcattattaa gcggtaaatt agaccaatat attcaaaaca
0911 gaaaaaccgt cagtattatt tccggcggca atatcgatct ttctcgcgtc tctcaaatca ccggtttcgt
0981 tgacgcttaa ttaattcgtt gaggatagga tatgagtact tcagatagca ttgtatccag ccagacaaaa
1051 caatcgtcct ggcgtaaatc agataccaca tggacgttag
|
