MG1655
W3110
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Gene Report : ppiC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion OCR02-4 (D)  ,  OCR02-11 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  ppiC
Related strains
     Strains Search Search strains by gene name:  ppiC   Search strains by all related name:  ppiC b3775 ECK3767 JW3748 parvA

General information  (Go to Linear View:)
 Gene Name ppiC  
 Alternative name b3775,ECK3767,JW3748,parvA  
 Location, Length 3,957,555 - 3,957,836 (  -  ) ;   85.30 min ; 282 (bp) ,   93 (aa) Go to Linear View
 Product peptidyl-prolyl cis-trans isomerase C (rotamase C)  
 Operon Name ppiC  
 Note GO_process: GO:0006457 - protein folding  
 Function enzyme; Proteins - translation and modification  
 Gene Ontology GO:0003755 ; peptidyl-prolyl cis-trans isomerase activity ( ppiC )
GO:0005737 ; cytoplasm ( ppiC )
GO:0006457 ; protein folding ( ppiC )
GO:0016853 ; isomerase activity ( ppiC )
 PID 1790211  
 EC number
  (KEGG Pathway)
 
5.2.1.8  
Verified Protein Starts (data compiled from literature and appropriate citations are available from EcoGene)
     EcoGene ppiC ( EG12352 )  
    Number of removed 1 aa cleaved  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) PPIC_ECOLI ( P39159 )
    -  Protein name Peptidyl-prolyl cis-trans isomerase C  
    -  Synonyms EC 5.2.1.8, PPIase C, Rotamase C, Parvulin  
    -  Gene name OrderedLocusNames=b3775, c4697, z5286, ECs4709;  

 Linear View (Whole Mode)
View Location
   3945.0  –  3970.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP ppiC (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Nmr Structure Of The E. Coli Peptidyl-Prolyl CisTRANS- Isomerase Parvulin 10  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Peptidyl-prolyl cis-trans isomerase C (PPIase C) (Rotamase C) (Parvulin)  
         PSI-BLAST Chaperone surA precursor
    nr     (database updated : 2007.02.20 )
         BLAST peptidyl-prolyl cis-trans isomerase C (rotamase C) [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    MYRISTYL    AMIDATION    PPIC_PPIASE     

Other Cross-Reference
    COG COG0760O 
    EcoCyc ppiC 

MMBR References
Trends Biochem Sci. 1995;20(1):12-4.
A new family of peptidyl-prolyl isomerases.
Rudd KE, Sofia HJ, Koonin EV, Plunkett G 3rd, Lazar S, Rouviere PE. ( 7878731 )

Sequences
Amino acid
FASTA format
0001 MAKTAAALHI LVKEEKLALD LLEQIKNGAD FGKLAKKHSI CPSGKRGGDL GEFRQGQMVP AFDKVVFSCP 
0071 VLEPTGPLHT QFGYHIIKVL YRN

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             tgccatatat gtaccagcca ctccctgact 
-070 gacaattacg ttagcatctg cggatcatgc taaaatcgcc gcctgacaat tattcactca aggcacgatc 
0001 atggcaaaaa cagcagcagc actgcatatc cttgtaaaag aagagaaact ggctctggat cttctcgagc 
0071 agattaagaa cggggccgat ttcggcaagc tggcgaagaa acactccatt tgcccatcag gcaaacgcgg 
0141 cggtgattta ggtgaattcc gccagggtca gatggttccg gcgttcgata aagtggtttt ctcttgtccg 
0211 gtactggagc cgaccggccc gctgcacacc cagttcggat atcacatcat taaggtgctg taccgcaact 
0281 aatagcaagg ccttctccag gagaaggcct tgagtgtttt ctccctctcc ctgtgggaga gggtcggggt 
0351 gagggcatca gcgcgcactt aacccgcaac ag