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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
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OCL21
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
kefB
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Related strains
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Strains Search
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Search strains by gene name:
kefB
Search strains by all related name:
kefB b3350 ECK3338 f601 JW3313 trkB
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General information (Go to Linear View: )
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Gene Name
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kefB
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Alternative name
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b3350,ECK3338,f601,JW3313,trkB
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Location, Length
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3,476,824 - 3,478,629
(
-
)
;
74.94
min
;
1806
(bp) ,
601
(aa)
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Product
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potassium:proton antiporter
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Operon Name
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kefGB-yheV
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Note
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K+ efflux; NEM-activable K+/H+ antiporter; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_function: GO:0015386 - potassium:hydrogen antiporter activity
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Function
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transport; Transport of small molecules: Cations
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Gene Ontology
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GO:0003824
;
catalytic activity ( kefB )
GO:0005488
;
binding ( kefB )
GO:0005886
;
plasma membrane ( kefB )
GO:0006810
;
transport ( kefB )
GO:0006811
;
ion transport ( kefB )
GO:0006812
;
cation transport ( kefB )
GO:0006813
;
potassium ion transport ( kefB )
GO:0006885
;
regulation of pH ( kefB )
GO:0008152
;
metabolic process ( kefB )
GO:0008324
;
cation transmembrane transporter activity ( kefB )
GO:0015297
;
antiporter activity ( kefB )
GO:0015299
;
solute:hydrogen antiporter activity ( kefB )
GO:0015503
;
glutathione-regulated potassium exporter activity ( kefB )
GO:0016020
;
membrane ( kefB )
GO:0016021
;
integral to membrane ( kefB )
GO:0030955
;
potassium ion binding ( kefB )
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PID
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1789749
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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KEFB_ECOLI
(
P45522
)
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- Protein name
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Glutathione-regulated potassium-efflux system protein kefB (K(+)/H(+) antiporter) (NEM-activatable K
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- Synonyms
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+)/H(+) antiporter
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- Gene name
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Name=kefB; Synonyms=trkB; OrderedLocusNames=b3350;
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MMBR References
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J Bacteriol. 1998;180:1030-1036
Importance of RpoS and Dps in survival of exposure of both exponential- and stationary-phase Escherichia coli cells to the electrophile N-ethylmaleimide.
Ferguson, G. P., R. I. Creighton, Y. Nikolaev, and I. R. Booth.
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J Bacteriol. 1987;169(8):3743-9.
Evidence for multiple K+ export systems in Escherichia coli.
Bakker EP, Booth IR, Dinnbier U, Epstein W, Gajewska A.
(
3301813
)
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| Sequences |
Amino acid
FASTA format
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0001 MEGSDFLLAG VLFLFAAVAA VPLASRLGIG AVLGYLLAGI AIGPWGLGFI SDVDEILHFS ELGVVFLMFI
0071 IGLELNPSKL WQLRRSIFGV GAAQVLLSAA LLAGLLMLTD FAWQAAVVGG IGLAMSSTAM ALQLMREKGM
0141 NRSESGQLGF SVLLFQDLAV IPALALVPLL AGSADEHFDW MKVGMKVLAF VGMLIGGRYL LRPVFRFIAA
0211 SGVREVFTAA TLLLVLGSAL FMDALGLSMA LGTFIAGVLL AESEYRHELE TAIDPFKGLL LGLFFISVGM
0281 SLNLGVLYTH LLWVVISVVV LVAVKILVLY LLARLYGVRS SERMQFAGVL SQGGEFAFVL FSTASSQRLF
0351 QGDQMALLLV TVTLSMMTTP LLMKLVDKWL SRQFNGPEEE DEKPWVNDDK PQVIVVGFGR FGQVIGRLLM
0421 ANKMRITVLE RDISAVNLMR KYGYKVYYGD ATQVDLLRSA GAEAAESIVI TCNEPEDTMK LVEICQQHFP
0491 HLHILARARG RVEAHELLQA GVTQFSRETF SSALELGRKT LVTLGMHPHQ AQRAQLHFRR LDMRMLRELI
0561 PMHADTVQIS RAREARRELE EIFQREMQQE RRQLDGWDEF E
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ttatttactg ggcgagacgg caaagcgcac
-070 aggagctggc gagccacgcc agagcctacg gtgactggct ggcaaatccg ctgtctccag gaggccgctg
0001 atggaaggtt ccgatttttt actcgcagga gtgctgtttc tcttcgcggc ggtggctgcg gtgccgctgg
0071 catcgcggct gggtattggc gctgtgttgg gatatttgct ggcagggatt gcaattggcc cgtgggggct
0141 ggggtttatt agcgacgtcg atgagatcct ccacttttcg gaactcggcg tggtattcct gatgtttatc
0211 atcggccttg agttgaatcc ctccaaactt tggcaactgc ggcgttcgat ttttggcgta ggcgcggcac
0281 aggtgctgtt aagcgcggcg ttgctggcgg gattattgat gctgacggat ttcgcctggc aggcggcggt
0351 ggtcggtggc attggccttg cgatgtcttc aactgcaatg gcgttgcaat tgatgcgtga gaaagggatg
0421 aatcgcagcg aatccggcca gctcgggttt tcggttctgc tgtttcagga tctggcagta atcccagcac
0491 tggcgttagt gccgttgttg gcggggtcgg cagacgaaca tttcgactgg atgaaggtcg gcatgaaggt
0561 gctggcgttt gtcggcatgc tgattggtgg gcgctattta ctgcgtccgg tattccgctt tattgcagct
0631 tctggcgtgc gggaagtgtt caccgccgcg acgctgctgc tggtgttggg ttccgcattg tttatggatg
0701 cgctggggct gtcgatggcg ctcggtacat ttattgcggg cgtgctgctg gcggaaagtg aatatcgcca
0771 tgaactggaa acggctatcg atcccttcaa aggcttgctg ctcggtttgt tctttatctc tgtcggcatg
0841 tcactcaacc tcggggtgct ttatacccat ctgttgtggg tagtgataag cgtggttgtg ctggtggcgg
0911 tgaaaattct cgtgctgtat ctgctggcgc gattgtatgg cgtgcgtagc tcagagcgga tgcagtttgc
0981 tggcgtgttg agtcagggtg gtgagtttgc ctttgtcctc ttttctaccg cttcttcaca acgcttattc
1051 cagggcgacc agatggcgtt gttgctggtg acggtgacgc tttccatgat gaccacgccg ttgctgatga
1121 agctggtgga taaatggcta tcccgccagt ttaacggacc ggaagaagaa gacgaaaaac cgtgggtcaa
1191 cgatgataaa ccccaggtca ttgtcgtggg cttcgggcgt tttggtcagg tgattggtcg tttgctgatg
1261 gcaaataaaa tgcgcattac cgtgctggag cgggatatca gcgccgttaa cctgatgcgt aaatacggct
1331 acaaagttta ttacggcgac gccacgcagg tcgatctttt acgttctgcg ggtgcagagg ccgctgagtc
1401 tatcgtcatt acctgtaacg agccggaaga caccatgaag ctggtggaaa tatgccaaca gcactttccg
1471 catttgcata ttcttgcgcg agcgcgcgga cgtgtggaag cgcatgagtt attacaggca ggggtgacgc
1541 agttttcccg tgaaacattc tccagtgcgt tagagctggg gcgcaagacg ctggtcacgc ttggcatgca
1611 tccgcatcag gcacagcgag cgcaactgca ttttcgccgc ctggatatgc ggatgctgcg agagctcatc
1681 ccaatgcatg ccgataccgt acaaatttct cgcgccaggg aagcccgacg cgaactggaa gagattttcc
1751 agcgtgaaat gcaacaagaa cgacgccagc tggacggctg ggatgaattt gagtagaggg taaagatggc
1821 aatccgaaaa cgttttattg cgggcgcaaa atgcccggcc tgtcaggcgc aggattcaat ggcgatgtgg
1891 cgcgaaaata atattg
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