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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
|
FEMS Microbiol Lett. 1992;73(1-2):175-80.
Sequence and characterization of the gcpE gene of Escherichia coli.
Baker J, Franklin DB, Parker J.
(
1521767
)
|
|
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Deletion
|
OCL56-20
(D)
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Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
ispG
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Related strains
|
|
Strains Search
|
Search strains by gene name:
ispG
Search strains by all related name:
ispG b2515 ECK2511 gcpE JW2499
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General information (Go to Linear View: )
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Gene Name
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ispG
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Alternative name
|
b2515,ECK2511,gcpE,JW2499
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Location, Length
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2,638,708 - 2,639,826
(
-
)
;
56.87
min
;
1119
(bp) ,
372
(aa)
|
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Product
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1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase
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Operon Name
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ispG-sroE
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Note
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Function
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Gene Ontology
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GO:0005506
;
iron ion binding ( ispG )
GO:0005515
;
protein binding ( ispG )
GO:0008299
;
isoprenoid biosynthetic process ( ispG )
GO:0016114
;
terpenoid biosynthetic process ( ispG )
GO:0016491
;
oxidoreductase activity ( ispG )
GO:0044237
;
cellular metabolic process ( ispG )
GO:0046429
;
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity ( ispG )
GO:0046872
;
metal ion binding ( ispG )
GO:0051536
;
iron-sulfur cluster binding ( ispG )
GO:0051539
;
4 iron, 4 sulfur cluster binding ( ispG )
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PID
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1788863
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EC number
(KEGG Pathway)
|
1.17.7.1
|
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
ISPG_ECOLI
(
P62620
;
P27433; P76984; P76985
)
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- Protein name
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4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
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- Synonyms
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EC 1.17.4.3, 1- hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase, GcpE protein, Protein E
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- Gene name
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Name=ispG; Synonyms=gcpE; OrderedLocusNames=b2515;
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MMBR References
|
FEMS Microbiol Lett. 1992;73(1-2):175-80.
Sequence and characterization of the gcpE gene of Escherichia coli.
Baker J, Franklin DB, Parker J.
(
1521767
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MHNQAPIQRR KSTRIYVGNV PIGDGAPIAV QSMTNTRTTD VEATVNQIKA LERVGADIVR VSVPTMDAAE
0071 AFKLIKQQVN VPLVADIHFD YRIALKVAEY GVDCLRINPG NIGNEERIRM VVDCARDKNI PIRIGVNAGS
0141 LEKDLQEKYG EPTPQALLES AMRHVDHLDR LNFDQFKVSV KASDVFLAVE SYRLLAKQID QPLHLGITEA
0211 GGARSGAVKS AIGLGLLLSE GIGDTLRVSL AADPVEEIKV GFDILKSLRI RSRGINFIAC PTCSRQEFDV
0281 IGTVNALEQR LEDIITPMDV SIIGCVVNGP GEALVSTLGV TGGNKKSGLY EDGVRKDRLD NNDMIDQLEA
0351 RIRAKASQLD EARRIDVQQV EK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 atctgagtcg ttttatcaga actaaccagg
-070 ttgcgcgtct gaccctcaat gccgaacaat caccggcgca gtaacagacg ggtaacgcgg gagatttttc
0001 atgcataacc aggctccaat tcaacgtaga aaatcaacac gtatttacgt tgggaatgtg ccgattggcg
0071 atggtgctcc catcgccgta cagtccatga ccaatacgcg tacgacagac gtcgaagcaa cggtcaatca
0141 aatcaaggcg ctggaacgcg ttggcgctga tatcgtccgt gtatccgtac cgacgatgga cgcggcagaa
0211 gcgttcaaac tcatcaaaca gcaggttaac gtgccgctgg tggctgacat ccacttcgac tatcgcattg
0281 cgctgaaagt agcggaatac ggcgtcgatt gtctgcgtat taaccctggc aatatcggta atgaagagcg
0351 tattcgcatg gtggttgact gtgcgcgcga taaaaacatt ccgatccgta ttggcgttaa cgccggatcg
0421 ctggaaaaag atctgcaaga aaagtatggc gaaccgacgc cgcaggcgtt gctggaatct gccatgcgtc
0491 atgttgatca tctcgatcgc ctgaacttcg atcagttcaa agtcagcgtg aaagcgtctg acgtcttcct
0561 cgctgttgag tcttatcgtt tgctggcaaa acagatcgat cagccgttgc atctggggat caccgaagcc
0631 ggtggtgcgc gcagcggggc agtaaaatcc gccattggtt taggtctgct gctgtctgaa ggcatcggcg
0701 acacgctgcg cgtatcgctg gcggccgatc cggtcgaaga gatcaaagtc ggtttcgata ttttgaaatc
0771 gctgcgtatc cgttcgcgag ggatcaactt catcgcctgc ccgacctgtt cgcgtcagga atttgatgtt
0841 atcggtacgg ttaacgcgct ggagcaacgc ctggaagata tcatcactcc gatggacgtt tcgattatcg
0911 gctgcgtggt gaatggccca ggtgaggcgc tggtttctac actcggcgtc accggcggca acaagaaaag
0981 cggcctctat gaagatggcg tgcgcaaaga ccgtctggac aacaacgata tgatcgacca gctggaagca
1051 cgcattcgtg cgaaagccag tcagctggac gaagcgcgtc gaattgacgt tcagcaggtt gaaaaataat
1121 aacgtgatgg gaagcgcctc gcttcccgtg tatgattgaa cccgcatggc tcccgaaaca ttgagggaag
1191 cgttgagggt tcatttttat attcagaaa
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