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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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Mol Microbiol. 1999;31(3):983-93.
Molecular characterization of Escherichia coli FtsE and FtsX.
de Leeuw E, Graham B, Phillips GJ, ten Hagen-Jongman CM, Oudega B, Luirink J.
(
10048040
)
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Deletion
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OCL17,18-1
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
ftsY
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Related strains
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Strains Search
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Search strains by gene name:
ftsY
Search strains by all related name:
ftsY b3464 ECK3448 JW3429
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General information (Go to Linear View: )
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Gene Name
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ftsY
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Alternative name
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b3464,ECK3448,JW3429
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Location, Length
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3,600,773 - 3,602,266
(
-
)
;
77.61
min
;
1494
(bp) ,
497
(aa)
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Product
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Signal Recognition Particle (SRP) receptor
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Operon Name
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ftsYEX
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Note
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cell division membrane protein; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
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Function
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membrane; Cell division
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Gene Ontology
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GO:0000166
;
nucleotide binding ( ftsY )
GO:0003723
;
RNA binding ( ftsY )
GO:0005525
;
GTP binding ( ftsY )
GO:0005886
;
plasma membrane ( ftsY )
GO:0006614
;
SRP-dependent cotranslational protein targeting to membrane ( ftsY )
GO:0007049
;
cell cycle ( ftsY )
GO:0008312
;
7S RNA binding ( ftsY )
GO:0016020
;
membrane ( ftsY )
GO:0017111
;
nucleoside-triphosphatase activity ( ftsY )
GO:0030529
;
ribonucleoprotein complex ( ftsY )
GO:0048500
;
signal recognition particle ( ftsY )
GO:0051301
;
cell division ( ftsY )
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PID
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1789874
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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FTSY_ECOLI
(
P10121
)
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- Protein name
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Cell division protein ftsY.
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- Synonyms
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- Gene name
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Name=ftsY; OrderedLocusNames=b3464;
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MMBR References
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Mol Gen Genet. 1986;205(1):134-45.
A new cell division operon in Escherichia coli.
Gill DR, Hatfull GF, Salmond GPC.
(
3025556
)
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FEBS Lett. 1995;372(2-3):253-8.
The functioning of the SRP receptor FtsY in protein-targeting in E. coli is correlated with its ability to bind and hydrolyse GTP.
Kusters R, Lentzen G, Eppens E, van Geel A, van der Weijden CC, Wintermeyer W, Luirink J.
(
7556679
)
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EMBO J. 1994;13:2289-2296
An alternative protein targeting pathway in Escherichia coli: studies on the role of FtsY.
Luirink, J., C. M. ten Hagen-Jongman, C. C. van der Weijden, B. Oudega, S. High, B. Dobberstein, and R. Kusters.
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Science. 1995;269(5229):1422-4.
Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases.
Powers T, Walter P.
(
7660124
)
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| Sequences |
Amino acid
FASTA format
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0001 MAKEKKRGFF SWLGFGQKEQ TPEKETEVQN EQPVVEEIVQ AQEPVKASEQ AVEEQPQAHT EAEAETFAAD
0071 VVEVTEQVAE SEKAQPEAEV VAQPEPVVEE TPEPVAIERE ELPLPEDVNA EAVSPEEWQA EAETVEIVEA
0141 AEEEAAKEEI TDEELETALA AEAAEEAVMV VPPAEEEQPV EEIAQEQEKP TKEGFFARLK RSLLKTKENL
0211 GSGFISLFRG KKIDDDLFEE LEEQLLIADV GVETTRKIIT NLTEGASRKQ LRDAEALYGL LKEEMGEILA
0281 KVDEPLNVEG KAPFVILMVG VNGVGKTTTI GKLARQFEQQ GKSVMLAAGD TFRAAAVEQL QVWGQRNNIP
0351 VIAQHTGADS ASVIFDAIQA AKARNIDVLI ADTAGRLQNK SHLMEELKKI VRVMKKLDVE APHEVMLTID
0421 ASTGQNAVSQ AKLFHEAVGL TGITLTKLDG TAKGGVIFSV ADQFGIPIRY IGVGERIEDL RPFKADDFIE
0491 ALFARED
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gaattaagtt aagtgataga ctatttcatc
-070 atttttttag ctgctatgta catagcgtta acgctgtgcc atgaagcaac agcgaggagt gtagtcgcaa
0001 atggcgaaag aaaaaaaacg tggctttttt tcctggctgg gctttggtca aaaagagcag accccggaaa
0071 aagagacaga agttcagaat gaacaaccgg ttgtagaaga aatcgttcag gcgcaagagc ctgtgaaggc
0141 ctctgaacaa gccgttgaag agcagccgca agcgcatact gaagccgagg cggaaacttt tgctgccgac
0211 gttgtggaag tcactgaaca ggttgctgaa agtgaaaaag cgcagcctga agcggaagtc gttgcacagc
0281 cggaaccggt cgtagaagaa acgccggagc cagtggctat cgaacgtgaa gagctgccgt tgccggaaga
0351 cgtcaacgcc gaagcggttt cgccagaaga gtggcaggct gaagcggaaa ccgtagagat tgtcgaagcg
0421 gcggaagaag aagcggctaa agaagaaatt accgacgaag agctggaaac ggcgctggct gccgaagcgg
0491 cagaagaggc ggtgatggtg gttcctccgg cagaagaaga gcagccggtg gaagaaatcg ctcaggagca
0561 ggaaaaaccg accaaagaag gttttttcgc gcgcctgaaa cgcagcctgt taaaaaccaa agaaaatctc
0631 ggttccggat ttatcagcct gttccgcggt aaaaaaatcg acgatgatct gtttgaggag ctggaagagc
0701 agcttttgat cgccgatgtg ggtgtggaaa ccacacgtaa aattatcacc aatctgacgg aaggcgcatc
0771 ccgcaagcag cttcgtgacg ccgaggcgct ctatggcctg ctgaaagaag agatgggcga gattctggcg
0841 aaagtcgatg agccgctgaa tgttgaaggc aaagcgccgt ttgtgatcct gatggtgggc gtcaacggtg
0911 tgggtaaaac cacgacgatt ggtaagctgg cgcgtcagtt tgagcagcag ggtaaatcgg tgatgctggc
0981 ggcgggtgat actttccgtg cagctgcggt tgaacagctt caggtctggg gtcagcgcaa caatattccg
1051 gtgattgccc agcataccgg ggcggattcc gcctctgtta tcttcgacgc cattcaggca gctaaagcgc
1121 gtaatatcga cgtcctgatt gccgatacag ccggacgcct gcagaacaaa tcgcacctga tggaagagtt
1191 gaagaaaatc gtccgcgtga tgaagaaact cgacgttgaa gcgccgcatg aagttatgct gactattgat
1261 gccagcaccg ggcagaacgc ggtaagccag gccaaactgt tccatgaagc cgttggctta accggcatca
1331 cgctaacgaa actggacggc acggcgaaag gcggggtaat tttctcggtg gctgaccagt ttggtatccc
1401 tatccgctac attggtgtcg gcgaacgtat tgaggatttg cgtccgttta aggcggacga ctttatagag
1471 gcactttttg cccgagagga ttaacaatga ttcgctttga acatgtcagc aaggcttatc tcggtgggag
1541 acaggcgctg cagggcgtta cgttccatat gcagccgggt gagatggcgt ttct
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