|
PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
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|
References (PMID)
|
Mol Gen Genet. 1985;198(2):315-22.
Identification of the dadX gene coding for the predominant isozyme of alanine racemase in Escherichia coli K12.
Wild J, Hennig J, Lobocka M, Walczak W, Klopotowski T.
(
3920477
)
|
|
|
Deletion
|
OCR12,13-1
(D)
,
OCR12,13-2
(D)
,
OCR12-18
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
alr
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
alr
Search strains by all related name:
alr b4053 ECK4045 JW4013 o359
|
General information (Go to Linear View: )
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Gene Name
|
alr
|
|
Alternative name
|
b4053,ECK4045,JW4013,o359
|
|
Location, Length
|
4,263,805 - 4,264,884
(
+
)
;
91.90
min
;
1080
(bp) ,
359
(aa)
|
|
Product
|
alanine racemase 1, PLP-binding, biosynthetic
|
|
Operon Name
|
alr
|
|
Note
|
alanine racemase 1; GO_process: GO:0006523 - alanine biosynthetic process
|
|
Function
|
enzyme; Amino acid biosynthesis: Alanine
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( alr )
GO:0006522
;
alanine metabolic process ( alr )
GO:0007047
;
cell wall organization and biogenesis ( alr )
GO:0008360
;
regulation of cell shape ( alr )
GO:0008784
;
alanine racemase activity ( alr )
GO:0009252
;
peptidoglycan biosynthetic process ( alr )
GO:0016853
;
isomerase activity ( alr )
GO:0030170
;
pyridoxal phosphate binding ( alr )
|
|
PID
|
1790487
|
EC number
(KEGG Pathway)
|
5.1.1.1
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
ALR1_ECOLI
(
P29743
;
P78136
)
|
|
- Protein name
|
Alanine racemase, biosynthetic
|
|
- Synonyms
|
EC 5.1.1.1
|
|
- Gene name
|
Name=alr; OrderedLocusNames=b4053, SF4152, S3578;
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MMBR References
|
Gene. 1993;129(1):9-16.
The 92-min region of the Escherichia coli chromosome: location and cloning of the ubiA and alr genes.
Lilley PE, Stamford NP, Vasudevan SG, Dixon NE.
(
8335265
)
|
Nucleic Acids Res. 1993;21:5408-5417
Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.
Blattner, F. R., V. D. Burland, G. Plunkett, H. J. Sofia, and D. L. Daniels.
|
| Sequences |
Amino acid
FASTA format
|
0001 MQAATVVINR RALRHNLQRL RELAPASKMV AVVKANAYGH GLLETARTLP DADAFGVARL EEALRLRAGG
0071 ITKPVLLLEG FFDARDLPTI SAQHFHTAVH NEEQLAALEE ASLDEPVTVW MKLDTGMHRL GVRPEQAEAF
0141 YHRLTQCKNV RQPVNIVSHF ARADEPKCGA TEKQLAIFNT FCEGKPGQRS IAASGGILLW PQSHFDWVRP
0211 GIILYGVSPL EDRSTGADFG CQPVMSLTSS LIAVREHKAG EPVGYGGTWV SERDTRLGVV AMGYGDGYPR
0281 AAPSGTPVLV NGREVPIVGR VAMDMICVDL GPQAQDKAGD PVILWGEGLP VERIAEMTKV SAYELITRLT
0351 SRVAMKYVD
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TGGTCGCGCT TCGACAACTA TGCGGGGCCG
-070 CAGTACGACG ACGAATAATA ATTATTTTAT GAATTAGGTA ATTAAAGCAA ACACTTATCA AGGAACACAA
0001 atgcaagcgg caactgttgt gattaaccgc cgcgctctgc gacacaacct gcaacgtctt cgtgaactgg
0071 cccctgccag taaaatggtt gcggtggtga aagcgaacgc ttatggtcac ggtcttcttg agaccgcgcg
0141 aacgctcccc gatgctgacg cctttggcgt agcccgtctc gaagaagctc tgcgactgcg tgcgggggga
0211 atcaccaaac ctgtactgtt actcgaaggc ttttttgatg ccagagatct gccgacgatt tctgcgcaac
0281 attttcatac cgccgtgcat aacgaagaac agctggctgc gctggaagag gctagcctgg acgagccggt
0351 taccgtctgg atgaaactcg ataccggtat gcaccgtctg ggcgtaaggc cggaacaggc tgaggcgttt
0421 tatcatcgcc tgacccagtg caaaaacgtt cgtcagccgg tgaatatcgt cagccatttt gcgcgcgcgg
0491 atgaaccaaa atgtggcgca accgagaaac aactcgctat ctttaatacc ttttgcgaag gcaaacctgg
0561 tcaacgttcc attgccgcgt cgggtggcat tctgctgtgg ccacagtcgc attttgactg ggtgcgcccg
0631 ggcatcattc tttatggcgt ctcgccgctg gaagatcgct ccaccggtgc cgattttggc tgtcagccag
0701 tgatgtcact aacctccagc ctgattgccg tgcgtgagca taaagccgga gagcctgttg gttatggtgg
0771 aacctgggta agcgaacgtg atacccgtct tggcgtagtc gcgatgggct atggcgatgg ttatccgcgc
0841 gccgcgccgt ccggtacgcc agtgctggtg aacggtcgcg aagtaccgat tgtcgggcgc gtggcgatgg
0911 atatgatctg cgtagactta ggtccacagg cgcaggacaa agccggggat ccggtcattt tatggggcga
0981 aggtttgccc gtagaacgta tcgctgaaat gacgaaagta agcgcttacg aacttattac gcgcctgact
1051 tcaagggtcg cgatgaaata cgtggattaa TCGTTCTGTA ATATTTGATT GTCTGTGCCG GATGCGGCGT
1121 GAATGCCTTA TCCGGCCAAT AAAATCCTAA AAATTCAATA AGTTGATGTT CTTTCATGCT
|
