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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
|
J Bacteriol. 1993;175(21):6881-9.
Organization and nucleotide sequences of the genes encoding the biotin carboxyl carrier protein and biotin carboxylase protein of Pseudomonas aeruginosa acetyl coenzyme A carboxylase.
Best EA, Knauf VC.
(
7693652
)
|
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Deletion
|
OCL64
(D)
,
OCL64-9
(D)
|
|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
accD
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Related strains
|
|
Strains Search
|
Search strains by gene name:
accD
Search strains by all related name:
accD b2316 dedB ECK2310 JW2313 usg
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General information (Go to Linear View: )
|
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Gene Name
|
accD
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Alternative name
|
b2316,dedB,ECK2310,JW2313,usg
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|
Location, Length
|
2,431,034 - 2,431,948
(
-
)
;
52.40
min
;
915
(bp) ,
304
(aa)
|
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Product
|
acetyl-CoA carboxylase, beta (carboxyltransferase) subunit
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Operon Name
|
accD
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Note
|
acetylCoA carboxylase, carboxytransferase component, beta subunit; GO_component: GO:0005737 - cytoplasm
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Function
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enzyme; Fatty acid and phosphatidic acid biosynthesis
|
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Gene Ontology
|
GO:0003824
;
catalytic activity ( usg )
GO:0003989
;
acetyl-CoA carboxylase activity ( accD )
GO:0004073
;
aspartate-semialdehyde dehydrogenase activity ( usg )
GO:0005488
;
binding ( usg )
GO:0005515
;
protein binding ( usg )
GO:0005515
;
protein binding ( accD )
GO:0005737
;
cytoplasm ( usg )
GO:0006520
;
amino acid metabolic process ( usg )
GO:0006633
;
fatty acid biosynthetic process ( accD )
GO:0008152
;
metabolic process ( usg )
GO:0008270
;
zinc ion binding ( accD )
GO:0008610
;
lipid biosynthetic process ( accD )
GO:0008652
;
amino acid biosynthetic process ( usg )
GO:0009317
;
acetyl-CoA carboxylase complex ( accD )
GO:0016620
;
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor ( usg )
GO:0016874
;
ligase activity ( accD )
GO:0046872
;
metal ion binding ( accD )
GO:0046983
;
protein dimerization activity ( usg )
GO:0050661
;
NADP binding ( usg )
GO:0051287
;
NAD binding ( usg )
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PID
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1788655
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EC number
(KEGG Pathway)
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6.4.1.2
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SWISS-PROT
(
Show details
[
4
more]
)
|
Entry name(Acc.no)
|
ACCD_ECOLI
(
P08193
;
P76937; P78251
)
|
|
- Protein name
|
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
|
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- Synonyms
|
EC 6.4.1.2, ACCase beta chain
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- Gene name
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OrderedLocusNames=b2316, z3578, ECs3200;
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MMBR References
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J Bacteriol. 1992;174(17):5755-7.
The dedB (usg) open reading frame of Escherichia coli encodes a subunit of acetyl-coenzyme A carboxylase.
Li SJ, Rock CO, Cronan JE Jr.
(
1355086
)
|
J Bacteriol. 1993;175:332-340
Growth rate regulation of Escherichia coli acetyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis.
Li, S.-J., and J. E. Cronan, Jr.
|
Mol Gen Genet. 1991;228(1-2):62-4.
An essential gene of Escherichia coli that has sequence similarity to a chloroplast gene of unknown function.
Nagano Y, Matsuno R, Sasaki Y.
(
1886618
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MSWIERIKSN ITPTRKASIP EGVWTKCDSC GQVLYRAELE RNLEVCPKCD HHMRMTARNR LHSLLDEGSL
0071 VELGSELEPK DVLKFRDSKK YKDRLASAQK ETGEKDALVV MKGTLYGMPV VAAAFEFAFM GGSMGSVVGA
0141 RFVRAVEQAL EDNCPLICFS ASGGARMQEA LMSLMQMAKT SAALAKMQER GLPYISVLTD PTMGGVSASF
0211 AMLGDLNIAE PKALIGFAGP RVIEQTVREK LPPGFQRSEF LIEKGAIDMI VRRPEMRLKL ASILAKLMNL
0281 PAPNPEAPRE GVVVPPVPDQ EPEA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ttaatgtgca acattcatgg tctgttgggg
-070 gcaaaaatgg cattatgcgt ccccaaagat aaaactggca tcgaaccagg ttcagacaga aaggtcccta
0001 atgagctgga ttgaacgaat taaaagcaac attactccca cccgcaaggc gagcattcct gaaggggtgt
0071 ggactaagtg tgatagctgc ggtcaggttt tataccgcgc tgagctggaa cgtaatcttg aggtctgtcc
0141 gaagtgtgac catcacatgc gtatgacagc gcgtaatcgc ctgcatagcc tgttagatga aggaagcctt
0211 gtggagctgg gtagcgagct tgagccgaaa gatgtgctga agtttcgtga ctccaagaag tataaagacc
0281 gtctggcatc tgcgcagaaa gaaaccggcg aaaaagatgc gctggtggtg atgaaaggca ctctgtatgg
0351 aatgccggtt gtcgctgcgg cattcgagtt cgcctttatg ggcggttcaa tggggtctgt tgtgggtgca
0421 cgtttcgtgc gtgccgttga gcaggcgctg gaagataact gcccgctgat ctgcttctcc gcctctggtg
0491 gcgcacgtat gcaggaagca ctgatgtcgc tgatgcagat ggcgaaaacc tctgcggcac tggcaaaaat
0561 gcaggagcgc ggcttgccgt acatctccgt gctgaccgac ccgacgatgg gcggtgtttc tgcaagtttc
0631 gccatgctgg gcgatctcaa catcgctgaa ccgaaagcgt taatcggctt tgccggtccg cgtgttatcg
0701 aacagaccgt tcgcgaaaaa ctgccgcctg gattccagcg cagtgaattc ctgatcgaga aaggcgcgat
0771 cgacatgatc gtccgtcgtc cggaaatgcg cctgaaactg gcgagcattc tggcgaagtt gatgaatctg
0841 ccagcgccga atcctgaagc gccgcgtgaa ggcgtagtgg tacccccggt accggatcag gaacctgagg
0911 cctgataact gataagggca gggccactgg ctctgccctt ttgctattct caccgtaacg aatcagcgga
0981 taccatgatt atcaaacgca ctcctcaagc cgcgt
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