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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Proc Natl Acad Sci U S A. 1994;91(20):9223-7.
A tRNA-like structure is present in 10Sa RNA, a small stable RNA from Escherichia coli.
Komine Y, Kitabatake M, Yokogawa T, Nishikawa K, Inokuchi H.
(
7524073
)
|
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Deletion
|
OCL51
(D)
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Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
ssrA
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Related strains
|
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Strains Search
|
Search strains by gene name:
ssrA
Search strains by all related name:
ssrA b2621 ECK2617 JWR0055 sipB
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General information (Go to Linear View: )
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tmRNA Name
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ssrA
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Alternative name
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b2621,ECK2617,JWR0055,sipB
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Location, Length
|
2,753,615 - 2,753,977
(
+
)
;
59.35
min
;
363
(bp) ,
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Product
|
tmRNA, 10Sa RNA
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Operon Name
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ssrA
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Note
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acts as tRNA-Ala and mRNA template for tagging proteins resulting from premature transcription termination for degradation, a process known as trans-translation
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Function
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2.2.6 information transfer; RNA related; rRNA, stable RNA,2.3.6 information transfer; protein related; turnover, degradation,6.6 cell structure; ribosome,7.1 location of gene products; cytoplasm,RNA; Ribosomal and stable RNAs
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Gene Ontology
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PID
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EC number
(KEGG Pathway)
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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PSI-BLAST
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nr
(database updated :
2007.02.20
)
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BLAST
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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MMBR References
|
Genes Genet Syst. 1996;71(1):47-50.
10Sa RNA complements the temperature-sensitive phenotype caused by a mutation in the phosphoribosyl pyrophosphate synthetase (prs) gene in Escherichia coli.
Ando H, Kitabatake M, Inokuchi H.
(
8925474
)
|
Biochimie. 1996;78(11-12):979-83.
Structural organization of Escherichia coli tmRNA.
Felden B, Himeno H, Muto A, Atkins JF, Gesteland RF.
(
9150875
)
|
J Bacteriol. 1991;173(17):5252
Physical map locations of the genes that encode small stable RNAs in Escherichia coli.
Komine Y, Inokuchi H.
(
1715853
)
|
J. Biochem. (Tokyo) 1996;119:463-467
10Sa RNA is associated with 70S ribosome particles in Escherichia coli.
Komine, Y., M. Kitabatake, and H. Inokuchi.
|
Biochimie. 1996;78(11-12):985-91.
Structure and function of 10Sa RNA: trans-translation system.
Muto A, Sato M, Tadaki T, Fukushima M, Ushida C, Himeno H.
(
9150876
)
|
J Bacteriol. 1990;172(8):4708-9.
Location of a gene (ssrA) for a small, stable RNA (10Sa RNA) in the Escherichia coli chromosome.
Oh BK, Chauhan AK, Isono K, Apirion D.
(
1695897
)
|
Mol Gen Genet. 1991;229(1):52-6.
10Sa RNA, a small stable RNA of Escherichia coli, is functional.
Oh BK, Apirion D.
(
1716727
)
|
Cell. 1995;83(2):227-35.
A role for a small stable RNA in modulating the activity of DNA-binding proteins.
Retallack DM, Friedman DI.
(
7585940
)
|
J Bacteriol. 1994;176:2082-2089
Role for 10Sa RNA in the growth of lambda-P22 hybrid phage.
Retallack, D. M., L. L. Johnson, and D. I. Friedman.
|
Mol Microbiol. 1989;3(11):1481-5.
The gene for a small stable RNA (10Sa RNA) of Escherichia coli.
Chauhan AK, Apirion D.
(
2482406
)
|
| Sequences |
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CGAATAAAAA TCAGGCTACA TGGGTGCTAA
-070 ATCTTTAACG ATAACGCCAT TGAGGCTGGT CATGGCGCTC ATAAATCTGG TATACTTACC TTTACACATT
0001 ggggctgatt ctggattcga cgggatttgc gaaacccaag gtgcatgccg aggggcggtt ggcctcgtaa
0071 aaagccgcaa aaaatagtcg caaacgacga aaactacgct ttagcagctt aataacctgc ttagagccct
0141 ctctccctag cctccgctct taggacgggg atcaagagag gtcaaaccca aaagagatcg cgtggaagcc
0211 ctgcctgggg ttgaagcgtt aaaacttaat caggctagtt tgttagtggc gtgtccgtcc gcagctggca
0281 agcgaatgta aagactgact aagcatgtag taccgaggat gtaggaattt cggacgcggg ttcaactccc
0351 gccagctcca ccaAAATTCT CCATCGGTGA TTACCAGAGT CATCCGATGA AGTCCTAAGA GCCCGCACGG
0421 CGCAAGCCCT GCGGGCTTTT TTGTGCCCTC AATTTGTCCC GCG
|
