MG1655
W3110
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Gene Report : sulA
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Mol Gen Genet. 1997;254(4):351-7.
Functional dissection of a cell-division inhibitor, SulA, of Escherichia coli and its negative regulation by Lon.
Higashitani A, Ishii Y, Kato Y, Koriuchi K. ( 9180687 )
     Deletion OCR56 (D)  ,  OCR56-3 (D)  ,  OCR56-7 (D)  ,  OCR56-8 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  sulA
Related strains
     Strains Search Search strains by gene name:  sulA   Search strains by all related name:  sulA b0958 ECK0949 JW0941 sfiA

General information  (Go to Linear View:)
 Gene Name sulA  
 Alternative name b0958,ECK0949,JW0941,sfiA  
 Location, Length 1,019,633 - 1,020,142 (  -  ) ;   21.98 min ; 510 (bp) ,   169 (aa) Go to Linear View
 Product SOS cell division inhibitor  
 Operon Name sulA  
 Note suppressor of lon; inhibits cell division and ftsZ ring formation; GO_component: GO:0042597 - periplasmic space; GO_process: GO:0006281 - DNA repair; GO_process: GO:0009432 - SOS response  
 Function phenotype; Cell division  
 Gene Ontology GO:0000917; barrier septum formation ( sulA )
GO:0005886; plasma membrane ( sulA )
GO:0006281; DNA repair ( sulA )
GO:0006974; response to DNA damage stimulus ( sulA )
GO:0007049; cell cycle ( sulA )
GO:0009276; 1-2nm peptidoglycan-based cell wall ( sulA )
GO:0009432; SOS response ( sulA )
GO:0016020; membrane ( sulA )
GO:0051301; cell division ( sulA )
 PID 1787192  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) SULA_ECOLI ( P08846 ; P03840; P71224 )
    -  Protein name Cell division inhibitor.  
    -  Synonyms  
    -  Gene name Name=sulA; Synonyms=sfiA; OrderedLocusNames=b0958, z1308, ECs1042;  

 Linear View (Whole Mode)
View Location
   1010.0  –  1035.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP sulA (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of Sula From Pseudomonas Aeruginosa  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Cell division inhibitor  
         PSI-BLAST Cell division inhibitor
    nr     (database updated : 2007.02.20 )
         BLAST SulA [Escherichia coli APEC O1]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CK2_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    EcoCyc sulA 

MMBR References
J Bacteriol. 1995;177:7141-7149
Expression and characterization of the Escherichia coli fdo locus and a possible role for aerobic formate dehydrogenase.
Abaibou, H., J. Pommier, S. Benoit, G. Giordano, and M.-A. Mandrand-Berthelot.

Sequences
Amino acid
FASTA format
0001 MYTSGYAHRS SSFSSAASKI ARVSTENTTA GLISEVVYRE DQPMMTQLLL LPLLQQLGQQ SRWQLWLTPQ 
0071 QKLSREWVQA SGLPLTKVMQ ISQLSPCHTV ESMVRALRTG NYSVVIGWLA DDLTEEEHAE LVDAANEGNA 
0141 MGFIMRPVSA SSHATRQLSG LKIHSNLYH

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             cgacaaaatt tgcgaggctc tttccgaaaa 
-070 tagggttgat ctttgttgtc actggatgta ctgtacatcc atacagtaac tcacaggggc tggattgatt 
0001 atgtacactt caggctatgc acatcgttct tcgtcgttct catccgcagc aagtaaaatt gcgcgtgtct 
0071 ctacggaaaa cactacagcc gggcttatca gtgaagttgt ctatcgcgaa gatcagccca tgatgacgca 
0141 acttctactg ttgccattgt tacagcaact cggtcagcaa tcgcgctggc aactctggtt aacaccgcaa 
0211 caaaaactga gtcgggaatg ggttcaggca tctgggctac ccttaacgaa agtaatgcag attagccagc 
0281 tctccccttg ccacactgtg gagtcaatgg ttcgcgcttt acgcacgggc aattacagtg tggtgatcgg 
0351 ttggttggca gatgatttga ctgaagaaga gcatgctgaa cttgttgatg cggcaaatga aggtaacgct 
0421 atggggttta ttatgcgtcc ggtaagcgca tcctctcacg ccacgagaca actttccggg ctaaaaattc 
0491 actctaattt gtatcattaa gtaaatttag gattaatcct ggaacttttt ttgtcgccca gccaatgctt 
0561 tcagtcgtga ctaattttcc ttgcggaggc ttgtctgaag cggtttccgc