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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
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OCR53,54-2
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
mukB
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Related strains
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Strains Search
|
Search strains by gene name:
mukB
Search strains by all related name:
mukB b0924 ECK0915 JW0907 o1486
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General information (Go to Linear View: )
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Gene Name
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mukB
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Alternative name
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b0924,ECK0915,JW0907,o1486
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Location, Length
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975,549 - 980,009
(
+
)
;
21.03
min
;
4461
(bp) ,
1486
(aa)
|
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Product
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chromosome condensin MukBEF, ATPase and DNA-binding subunit
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Operon Name
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smtA-mukFEB
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Note
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kinesin-like cell division protein involved in chromosome partitioning
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Function
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structural component; Cell division
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Gene Ontology
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GO:0000166
;
nucleotide binding ( mukB )
GO:0003677
;
DNA binding ( mukB )
GO:0005515
;
protein binding ( mukB )
GO:0005524
;
ATP binding ( mukB )
GO:0005737
;
cytoplasm ( mukB )
GO:0006260
;
DNA replication ( mukB )
GO:0007049
;
cell cycle ( mukB )
GO:0007059
;
chromosome segregation ( mukB )
GO:0007076
;
mitotic chromosome condensation ( mukB )
GO:0009295
;
nucleoid ( mukB )
GO:0030261
;
chromosome condensation ( mukB )
GO:0051301
;
cell division ( mukB )
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PID
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1787154
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EC number
(KEGG Pathway)
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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mukB
(
EG10618
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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MUKB_ECOLI
(
P22523
;
P71227; P77164; Q47398
)
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- Protein name
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Chromosome partition protein mukB
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- Synonyms
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Structural maintenance of chromosome related protein
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- Gene name
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Name=mukB; OrderedLocusNames=b0924;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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mukB
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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Chain A, Crystal Structure Of The N-Terminal Domain Of Mukb At 2.2a Resolution
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Chromosome partition protein mukB
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PSI-BLAST
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Chromosome partition protein mukB
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nr
(database updated :
2007.02.20
)
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BLAST
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cell division protein MukB [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
ATP_GTP_A
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MMBR References
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Antimicrob Agents Chemother. 1995;39:87-93
Frequency and mechanism of resistance to antibacterial action of ZM240401, (6S)-6-fluoro-shikimic acid.
Ewart, C. D., D. A. Jude, J. L. Thain, and W. W. Nichols.
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J Bacteriol. 1991;173(20):6643-6.
Partitioning of a mini-F plasmid into anucleate cells of the mukB null mutant.
Ezaki B, Ogura T, Niki H, Hiraga S.
(
1917886
)
|
Res Microbiol. 1991;142(2-3):189-94.
Mutants defective in chromosome partitioning in E. coli.
Hiraga S, Niki H, Imamura R, Ogura T, Yamanaka K, Feng J, Ezaki B, Jaffe A.
(
1925018
)
|
J Bacteriol. 1997;179:3494-3499
The Escherichia coli histone-like protein HU affects DNA initiation, chromosome partitioning via MukB, and cell division via MinCDE.
Jaffe, A., D. Vinella, and R. D'Ari.
|
EMBO J. 1991;10:183-193
The new gene mukB codes for a 177 kd protein with coiled-coil domains involved in chromosome partitioning of E. coli.
Niki, H., A. Jaffe, N. Imamura, T. Ogura, and S. Hiraga.
|
FEMS Microbiol Lett. 1996;143(2-3):211-6.
Carboxyl terminal region of the MukB protein in Escherichia coli is essential for DNA binding activity.
Saleh AZ, Yamanaka K, Niki H, Ogura T, Yamazoe M, Hiraga S.
(
8837474
)
|
Bioessays. 1995;17(6):527-36.
Overview of controls in the Escherichia coli cell cycle.
Vinella D, D'Ari R.
(
7575494
)
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| Sequences |
Amino acid
FASTA format
|
0001 MIERGKFRSL TLINWNGFFA RTFDLDELVT TLSGGNGAGK STTMAAFVTA LIPDLTLLHF RNTTEAGATS
0071 GSRDKGLHGK LKAGVCYSML DTINSRHQRV VVGVRLQQVA GRDRKVDIKP FAIQGLPMSV QPTQLVTETL
0141 NERQARVLPL NELKDKLEAM EGVQFKQFNS ITDYHSLMFD LGIIARRLRS ASDRSKFYRL IEASLYGGIS
0211 SAITRSLRDY LLPENSGVRK AFQDMEAALR ENRMTLEAIR VTQSDRDLFK HLISEATNYV AADYMRHANE
0281 RRVHLDKALE FRRELHTSRQ QLAAEQYKHV DMARELAEHN GAEGDLEADY QAASDHLNLV QTALRQQEKI
0351 ERYEADLDEL QIRLEEQNEV VAEAIERQQE NEARAEAAEL EVDELKSQLA DYQQALDVQQ TRAIQYNQAI
0421 AALNRAKELC HLPDLTADCA AEWLETFQAK ELEATEKMLS LEQKMSMAQT AHSQFEQAYQ LVVAINGPLA
0491 RNEAWDVARE LLREGVDQRH LAEQVQPLRM RLSELEQRLR EQQEAERLLA DFCKRQGKNF DIDELEALHQ
0561 ELEARIASLS DSVSNAREER MALRQEQEQL QSRIQSLMQR APVWLAAQNS LNQLSEQCGE EFTSSQDVTE
0631 YLQQLLERER EAIVERDEVG ARKNAVDEEI ERLSQPGGSE DQRLNALAER FGGVLLSEIY DDVSLEDAPY
0701 FSALYGPSRH AIVVPDLSQV TEHLEGLTDC PEDLYLIEGD PQSFDDSVFS VDELEKAVVV KIADRQWRYS
0771 RFPEVPLFGR AARESRIESL HAEREVLSER FATLSFDVQK TQRLHQAFSR FIGSHLAVAF ESDPEAEIRQ
0841 LNSRRVELER ALSNHENDNQ QQRIQFEQAK EGVTALNRIL PRLNLLADDS LADRVDEIRE RLDEAQEAAR
0911 FVQQFGNQLA KLEPIVSVLQ SDPEQFEQLK EDYAYSQQMQ RDARQQAFAL TEVVQRRAHF SYSDSAEMLS
0981 GNSDLNEKLR ERLEQAEAER TRAREALRGH AAQLSQYNQV LASLKSSYDT KKELLNDLQR ELQDIGVRAD
1051 SGAEERARIR RDELHAQLSN NRSRRNQLEK ALTFCEAEMD NLTRKLRKLE RDYFEMREQV VTAKAGWCAV
1121 MRMVKDNGVE RRLHRRELAY LSADDLRSMS DKALGALRLA VADNEHLRDV LRMSEDPKRP ERKIQFFVAV
1191 YQHLRERIRQ DIIRTDDPVE AIEQMEIELS RLTEELTSRE QKLAISSRSV ANIIRKTIQR EQNRIRMLNQ
1261 GLQNVSFGQV NSVRLNVNVR ETHAMLLDVL SEQHEQHQDL FNSNRLTFSE ALAKLYQRLN PQIDMGQRTP
1331 QTIGEELLDY RNYLEMEVEV NRGSDGWLRA ESGALSTGEA IGTGMSILVM VVQSWEDESR RLRGKDISPC
1401 RLLFLDEAAR LDARSIATLF ELCERLQMQL IIAAPENISP EKGTTYKLVR KVFQNTEHVH VVGLRGFAPQ
1471 LPETLPGTDE APSQAS
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GTCGCCTGAT TCGTGATGGC GAAGCAATGC
-070 CGATTGAAAA TCATCTGCAA CTCAACGATG AAACCGAAGA GAATCAGCCA GATAGCGGAG AGGAAGAATA
0001 atgattgaac gcggtaaatt tcgctcactg acgctgatta actggaacgg cttttttgcc cgaacttttg
0071 accttgacga gctggtcacg acgctttctg gcggtaacgg ggcgggtaaa tccaccacca tggcggcgtt
0141 cgttacggcg ctgatccccg acctgaccct gctgcatttc cgtaacacta cggaagccgg ggccaccagc
0211 ggttcgcgcg ataaaggtct gcacggtaag ctgaaagcgg gtgtctgtta ttcgatgctc gacaccatta
0281 actcgcgcca ccagcgcgtg gtggtcggtg tgcgtctgca acaggttgcc ggacgcgatc gtaaagtgga
0351 tatcaagccg tttgccattc agggactgcc gatgtcggtg cagccgacac agctggtgac cgaaaccctg
0421 aacgaacgcc aggcgcgcgt gctgccgctt aacgagctga aagacaagct cgaggcgatg gaaggcgtgc
0491 agtttaaaca gttcaactcc attactgatt accactcgct gatgttcgat ctgggcatca tcgcgcgtcg
0561 tctgcgctcc gcatctgacc gtagcaaatt ctatcgtctg atcgaagctt cgctgtatgg cgggatctcc
0631 agtgccatta cccgttctct gcgcgactac ctgttgccag aaaacagcgg cgtgcgtaaa gcgttccagg
0701 acatggaagc ggcgctgcgt gaaaaccgta tgacgctgga agcgattcgt gtcacccagt cggaccgcga
0771 cctgtttaag catctgatca gcgaagccac caactacgtg gcggcggact acatgcgtca cgccaacgag
0841 cgccgtgtcc atctcgacaa agccctggag tttcgtcgcg agctacatac ttcgcgtcag caactggcgg
0911 ctgagcagta caaacacgtc gatatggcgc gtgagctggc agagcacaac ggtgccgaag gcgatctgga
0981 agcggattat caggcggcca gtgatcacct gaacctggtg caaaccgcac tgcgtcagca ggagaagatc
1051 gaacgctacg aagcggatct cgatgagctg cagatccgtc tggaagagca aaatgaagtg gtggcagaag
1121 ccatcgaacg ccagcaagag aatgaggctc gtgcggaagc tgccgaactg gaagtggacg agctgaaaag
1191 ccagcttgct gactaccagc aggcgctgga cgtccagcaa acgcgcgcga tccagtataa ccaggcgatt
1261 gctgcgctta atcgtgccaa agaactgtgc catctgccgg acttaaccgc cgactgcgcc gccgaatggc
1331 tggaaacctt ccaggcgaaa gagctggaag cgactgaaaa aatgctctct cttgagcaga aaatgagcat
1401 ggcgcaaacc gcgcacagcc agtttgagca ggcttatcag ctggtggtgg caatcaacgg cccactggcg
1471 cgtaacgagg cgtgggatgt cgctcgcgaa ctattgcgcg aaggggtcga tcagcgtcac ctggcagagc
1541 aggttcagcc gctgcggatg cgattaagcg aactggaaca gcgtctacgc gagcagcaag aagctgagcg
1611 tctgctggca gatttctgca aacgtcaggg caagaatttt gatatcgacg aactggaagc cctgcatcag
1681 gaactggaag cacgcattgc ctctctttcc gatagcgtgt ctaacgcccg tgaagagcgc atggcactgc
1751 gccaggagca ggaacagctg cagtctcgca ttcagagttt gatgcagcgt gcgccggttt ggctggcagc
1821 gcaaaacagt ctcaaccagt tgagcgaaca gtgcggcgaa gagtttacct ccagccagga cgtcaccgaa
1891 tatctgcaac agttgctgga gcgtgagcga gaggcgattg ttgaacgcga tgaagtgggc gcgcgcaaaa
1961 acgccgtcga tgaagagatc gaacgtttaa gccagcctgg cggctctgaa gatcagcgtc tgaacgcgct
2031 ggcggagcgt tttggtggtg tgctgctgtc agaaatttat gacgacgtta gcctggaaga tgcgccgtac
2101 ttctcagcgc tgtatggccc gtcacgccac gccatcgtgg tgccagatct gtcacaggta actgaacacc
2171 tggaaggctt gaccgattgc ccggaagatc tctatctgat cgaaggagat ccgcagtcat tcgatgacag
2241 cgtgttcagc gttgatgagc tggaaaaagc ggtagtggtg aaaatcgccg atcgtcagtg gcgttattca
2311 cgtttcccgg aagtgccgct gtttggtcgt gctgcgcgtg aaagccgtat tgaaagcctc catgccgagc
2381 gtgaagtgct ttccgaacgc ttcgccacgc tctcctttga tgtacagaaa actcagcgtc tgcatcaggc
2451 gttcagccgc tttatcggca gtcatctggc ggttgcgttt gagtctgacc cggaagcaga aatccgtcaa
2521 ctgaacagcc gtcgcgtcga actggagcgg gcgttaagta atcatgaaaa tgataaccag cagcagcgta
2591 ttcagtttga gcaggcgaaa gagggcgtta cggcgctgaa ccgcattctg ccgcgtctca acctgttggc
2661 tgatgacagc ctggcggatc gcgtcgatga aatccgcgaa cgtctggatg aagcccagga agccgcgcgt
2731 tttgttcagc agtttggcaa tcaactggcg aaactggaac cgattgtttc ggtattgcag agcgacccgg
2801 aacagttcga acagttaaaa gaagattacg cgtactctca gcagatgcag cgcgatgccc gtcagcaggc
2871 gtttgccctg acggaagtgg tgcagcgtcg tgcgcacttt agctattctg actcggcaga aatgcttagc
2941 ggtaacagcg atctcaacga aaaactgcgt gaacgtctgg aacaggcgga agcggagcgt acccgcgctc
3011 gcgaagcgtt gcgcggtcac gcagcgcagt tgagtcagta caaccaggtg ctggcttcgc tgaaaagttc
3081 ttacgacacc aaaaaagagc tactcaacga tctgcaacgt gaattgcagg atatcggcgt gcgtgctgat
3151 agcggggcag aagagcgggc gcgtattcgc cgtgacgagc tgcatgcgca actgagcaat aaccgttcac
3221 gccgcaatca actggaaaaa gcgcttacct tctgcgaagc ggagatggac aacctgaccc gcaaactgcg
3291 caagctggag cgggattact ttgagatgcg cgagcaggta gtgaccgcca aagcgggctg gtgtgcggtg
3361 atgcgcatgg tgaaagataa cggcgttgag cgccgcttac accgtcgtga gctggcttat ctctccgctg
3431 atgatttgcg ttccatgtcg gataaggcgt taggtgcgct gcgtctggcg gtggcggata acgaacatct
3501 gcgcgacgtg ctgcgcatgt cggaagatcc gaaacgtccg gagcgtaaaa ttcagttctt cgtggcggtt
3571 tatcagcatc tgcgtgaacg tattcgtcag gatattattc gtaccgatga tccggtggaa gctatcgaac
3641 agatggagat tgaacttagc cgtctgaccg aagaattaac ctcccgtgaa cagaaactgg cgatcagttc
3711 ccgcagcgtg gcgaacatca ttcgcaaaac cattcagcgc gagcagaacc gtatccgtat gctcaaccag
3781 gggttgcaga acgtatcgtt tggtcaggtg aacagcgtgc gtctcaacgt gaacgtgcgt gaaacgcacg
3851 ccatgctact ggatgtgctc tctgaacagc acgagcagca tcaggatctg tttaacagca accgtttgac
3921 cttctcggaa gcgctggcga aactgtatca acgtcttaac ccgcagattg atatggggca gcgcacgccg
3991 cagaccatcg gtgaagaact gctggattac cgcaactatc tggaaatgga agttgaggtt aaccgtggtt
4061 ccgatggctg gctgcgcgca gagtctggtg cattgtcgac cggtgaggcg attggtaccg gtatgtcgat
4131 tctggtgatg gtggtacaaa gctgggaaga tgaatctcgc cgcctgcgcg gtaaagatat ctctccttgc
4201 cgcctgctgt tcctcgatga agcagcgcga ctggatgctc gttctatcgc cacgctgttt gaattgtgtg
4271 agcgtttgca aatgcaactc atcatcgcag cgccggaaaa tatcagcccg gagaaaggca ccacctataa
4341 actggtgcgt aaagtcttcc agaataccga acacgttcat gtcgtcggcc tgcgaggatt tgcgccgcaa
4411 ctccctgaaa cgcttccagg aactgacgaa gcgccttctc aggcgagtta aAATTAAGGC GGCAGCAATG
4481 CCGCCTTTTC TTTTTCCGAA AACTCCGTTT CTGCACTAAA AAAGTGGCAC ATTACGGCGC GCTTTTCTTT
4551 AAACTTCTTT A
|
