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PEC Original Annotations
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|
Essentiality
|
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Class
|
non-essential
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References (PMID)
|
Gene. 1989;84(1):23-30.
Cloning and characterisation of the serC and aroA genes of Yersinia enterocolitica, and construction of an aroA mutant.
O'Gaora P, Maskel D, Coleman D, Cafferkey M, Dougan G.
(
2691337
)
|
|
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Deletion
|
OCR52
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
aroA
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
aroA
Search strains by all related name:
aroA b0908 ECK0899 JW0891
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General information (Go to Linear View: )
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Gene Name
|
aroA
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|
Alternative name
|
b0908,ECK0899,JW0891
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|
Location, Length
|
958,035 - 959,318
(
+
)
;
20.65
min
;
1284
(bp) ,
427
(aa)
|
|
Product
|
5-enolpyruvylshikimate-3-phosphate synthetase
|
|
Operon Name
|
serC-aroA
|
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Note
|
GO_process: GO:0009423 - chorismate biosynthetic process
|
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Function
|
enzyme; Amino acid biosynthesis: Chorismate
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( aroA )
GO:0003866
;
3-phosphoshikimate 1-carboxyvinyltransferase activity ( aroA )
GO:0005737
;
cytoplasm ( aroA )
GO:0008652
;
amino acid biosynthetic process ( aroA )
GO:0009073
;
aromatic amino acid family biosynthetic process ( aroA )
GO:0016740
;
transferase activity ( aroA )
GO:0016765
;
transferase activity, transferring alkyl or aryl (other than methyl) groups ( aroA )
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|
PID
|
1787137
|
EC number
(KEGG Pathway)
|
2.5.1.19
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
aroA
(
EG10073
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
AROA_ECOLI
(
P07638
;
P78222
)
|
|
- Protein name
|
3-phosphoshikimate 1-carboxyvinyltransferase
|
|
- Synonyms
|
EC 2.5.1.19, 5- enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS
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- Gene name
|
Name=aroA; OrderedLocusNames=b0908, z1254, ECs0991;
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MMBR References
|
FEBS Lett. 1984;170:59-63.
The complete amino acid sequence of Escherichia coli 5-enolpyruvylshikimate 3-phosphate synthase.
Duncan, K., A. Lewendon, and J. R. Coggins.
|
Biochem J. 1986;234(1):49-57.
The serC-aroA operon of Escherichia coli. A mixed function operon encoding enzymes from two different amino acid biosynthetic pathways.
Duncan K, Coggins JR.
(
3518706
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MESLTLQPIA RVDGTINLPG SKSVSNRALL LAALAHGKTV LTNLLDSDDV RHMLNALTAL GVSYTLSADR
0071 TRCEIIGNGG PLHAEGALEL FLGNAGTAMR PLAAALCLGS NDIVLTGEPR MKERPIGHLV DALRLGGAKI
0141 TYLEQENYPP LRLQGGFTGG NVDVDGSVSS QFLTALLMTA PLAPEDTVIR IKGDLVSKPY IDITLNLMKT
0211 FGVEIENQHY QQFVVKGGQS YQSPGTYLVE GDASSASYFL AAAAIKGGTV KVTGIGRNSM QGDIRFADVL
0281 EKMGATICWG DDYISCTRGE LNAIDMDMNH IPDAAMTIAT AALFAKGTTT LRNIYNWRVK ETDRLFAMAT
0351 ELRKVGAEVE EGHDYIRITP PEKLNFAEIA TYNDHRMAMC FSLVALSDTP VTILDPKCTA KTFPDYFEQL
0421 ARISQAA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ATGGTTGAGT TCGAACGCCG TCACGGTTAA
-070 TGCCGAAATT TTGCTTAATC CCCACAGCCA GCCTGTGGGG TTTTTATTTC TGTTGTAGAG AGTTGAGTTC
0001 atggaatccc tgacgttaca acccatcgct cgtgtcgatg gcactattaa tctgcccggt tccaagagcg
0071 tttctaaccg cgctttattg ctggcggcat tagcacacgg caaaacagta ttaaccaatc tgctggatag
0141 cgatgacgtg cgccatatgc tgaatgcatt aacagcgtta ggggtaagct atacgctttc agccgatcgt
0211 acgcgttgcg aaattatcgg taacggcggt ccattacacg cagaaggtgc cctggagttg ttcctcggta
0281 acgccggaac ggcaatgcgt ccgctggcgg cagctctttg tctgggtagc aatgatattg tgctgaccgg
0351 tgagccgcgt atgaaagaac gcccgattgg tcatctggtg gatgcgctgc gcctgggcgg ggcgaagatc
0421 acttacctgg aacaagaaaa ttatccgccg ttgcgtttac agggcggctt tactggcggc aacgttgacg
0491 ttgatggctc cgtttccagc caattcctca ccgcactgtt aatgactgcg cctcttgcgc cggaagatac
0561 ggtgattcgt attaaaggcg atctggtttc taaaccttat atcgacatca cactcaatct gatgaagacg
0631 tttggtgttg aaattgaaaa tcagcactat caacaatttg tcgtaaaagg cgggcagtct tatcagtctc
0701 cgggtactta tttggtcgaa ggcgatgcat cttcggcttc ttactttctg gcagcagcag caatcaaagg
0771 cggcactgta aaagtgaccg gtattggacg taacagtatg cagggtgata ttcgctttgc tgatgtgctg
0841 gaaaaaatgg gcgcgaccat ttgctggggc gatgattata tttcctgcac gcgtggtgaa ctgaacgcta
0911 ttgatatgga tatgaaccat attcctgatg cggcgatgac cattgccacg gcggcgttat ttgcaaaagg
0981 caccaccacg ctgcgcaata tctataactg gcgtgttaaa gagaccgatc gcctgtttgc gatggcaaca
1051 gaactgcgta aagtcggcgc ggaagtggaa gaggggcacg attacattcg tatcactcct ccggaaaaac
1121 tgaactttgc cgagatcgcg acatacaatg atcaccggat ggcgatgtgt ttctcgctgg tggcgttgtc
1191 agatacacca gtgacgattc ttgatcccaa atgcacggcc aaaacatttc cggattattt cgagcagctg
1261 gcgcggatta gccaggcagc ctgaATGAAC AACGGGCAAT AAATAGCCAA ATCTTTCTTT ATCAAAACGT
1331 CGGCACATTG TCGGCGTTTT TTTTCGGACC TTGTGAGTCA TTTTGATTAA TGGT
|
