|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Proc Natl Acad Sci U S A. 1990;87(1):360-3.
Mutations in the bglY gene increase the frequency of spontaneous deletions in Escherichia coli K-12.
Lejeune P, Danchin A.
(
2404280
)
|
|
|
Deletion
|
15
(LD)
,
DE(pgl-grxA)502
,
DE(galETK-chlA)
,
15+dps
(LD)
,
OCR48,49-5
(D)
,
OCR48,50-8 (LD 15D::Cm)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
bioC
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
bioC
Search strains by all related name:
bioC b0777 ECK0766 JW0760
|
General information (Go to Linear View: )
|
|
Gene Name
|
bioC
|
|
Alternative name
|
b0777,ECK0766,JW0760
|
|
Location, Length
|
810,745 - 811,500
(
+
)
;
17.47
min
;
756
(bp) ,
251
(aa)
|
|
Product
|
malonyl-CoA methyltransferase, SAM-dependent
|
|
Operon Name
|
bioBFCD
|
|
Note
|
biotin biosynthesis; reaction prior to pimeloyl CoA; GO_process: GO:0009102 - biotin biosynthetic process
|
|
Function
|
enzyme; Biosynthesis of cofactors, carriers: Biotin
|
|
Gene Ontology
|
GO:0008152
;
metabolic process ( bioC )
GO:0008168
;
methyltransferase activity ( bioC )
GO:0009102
;
biotin biosynthetic process ( bioC )
GO:0016740
;
transferase activity ( bioC )
|
|
PID
|
1786994
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
BIOC_ECOLI
(
P12999
)
|
|
- Protein name
|
Biotin synthesis protein bioC.
|
|
- Synonyms
|
|
|
- Gene name
|
Name=bioC; OrderedLocusNames=b0777;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
bioC
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Ph0226 Protein From Pyrococcus Horikoshii Ot3
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Biotin synthesis protein bioC
|
|
PSI-BLAST
|
Dimethyladenosine transferase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
predicted methltransferase, enzyme of biotin synthesis [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
|
|
MMBR References
|
Proc Natl Acad Sci U S A. 1968;61(3):956-62.
A deletion analysis of prophage lambda and adjacent genetic regions.
Adhya S, Cleary P, Campbell A.
(
5246560
)
|
Mol Microbiol. 1996;19(3):645-7.
To be free or not: the fate of pimelate in Bacillus sphaericus and in Escherichia coli.
Lemoine Y, Wach A, Jeltsch JM.
(
8830257
)
|
J. Microbiol. Serol. 1969;35:505-521
A genetical and biochemical study of chlorate-resistant mutants of Salmonella typhimurium. Antonie Leeuwenhoek.
Stouthamer, A. H.
|
Gene. 1982;19(1):93-103.
A physical map of the Escherichia coli bio operon.
Szybalski EH, Szybalski W.
(
6292053
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MATVNKQAIA AAFGRAAAHY EQHADLQRQS ADALLAMLPQ RKYTHVLDAG CGPGWMSRHW RERHAQVTAL
0071 DLSPPMLVQA RQKDAADHYL AGDIESLPLA TATFDLAWSN LAVQWCGNLS TALRELYRVV RPKGVVAFTT
0141 LVQGSLPELH QAWQAVDERP HANRFLPPDE IEQSLNGVHY QHHIQPITLW FDDALSAMRS LKGIGATHLH
0211 EGRDPRILTR SQLQRLQLAW PQQQGRYPLT YHLFLGVIAR E
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ATTCGCCCGC CAACCGTACC CGCTGGTACT
-070 GCGCGACTGC GCTTAACGCT AACCGCTGCG CATGAAATGC AGGATATCGA CCGTCTGCTG GAGGTGCTGC
0001 atggcaacgg ttaataaaca agccattgca gcggcatttg gtcgggcagc cgcacactat gagcaacatg
0071 cagatctaca gcgccagagt gctgacgcct tactggcaat gcttccacag cgtaaataca cccacgtact
0141 ggacgcgggt tgtggacctg gctggatgag ccgccactgg cgggaacgtc acgcgcaggt gacggcctta
0211 gatctctcgc cgccaatgct tgttcaggca cgccagaagg atgccgcaga ccattatctg gcgggagata
0281 tcgaatccct gccgttagcg actgcgacgt tcgatcttgc atggagcaat ctcgcagtgc agtggtgcgg
0351 taatttatcc acggcactcc gcgagctgta tcgggtggtg cgccccaaag gcgtggtcgc gtttaccacg
0421 ctggtgcagg gatcgttacc cgaactgcat caggcgtggc aggcggtgga cgagcgtccg catgctaatc
0491 gctttttacc gccagatgaa atcgaacagt cgctgaacgg cgtgcattat caacatcata ttcagcccat
0561 cacgctgtgg tttgatgatg cgctcagtgc catgcgttcg ctgaaaggca tcggtgccac gcatcttcat
0631 gaagggcgcg acccgcgaat attaacgcgt tcgcagttgc agcgattgca actggcctgg ccgcaacagc
0701 aggggcgata tcctctgacg tatcatcttt ttttgggagt gattgctcgt gagtaaACGT TATTTTGTCA
0771 CCGGAACGGA TACCGAAGTG GGGAAAACTG TCGCCAGTTG TGCACTTTTA CAAGCCGCAA AGGCAGCAGG
0841 CTACCGGACG GCAGGT
|
