MG1655
W3110
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Gene Report : nadD
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
     Deletion OCR46-11 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  nadD
Related strains
     Strains Search Search strains by gene name:  nadD   Search strains by all related name:  nadD b0639 ECK0632 f213 fusB JW0634 ybeN

General information  (Go to Linear View:)
 Gene Name nadD  
 Alternative name b0639,ECK0632,f213,fusB,JW0634,ybeN  
 Location, Length 669,154 - 669,795 (  -  ) ;   14.42 min ; 642 (bp) ,   213 (aa) Go to Linear View
 Product nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent  
 Operon Name leuS-lptE-holA-nadD-cobC  
 Note GO_process: GO:0009435 - NAD biosynthetic process  
 Function  
 Gene Ontology GO:0003824; catalytic activity ( nadD )
GO:0004515; nicotinate-nucleotide adenylyltransferase activity ( nadD )
GO:0009058; biosynthetic process ( nadD )
GO:0009435; NAD biosynthetic process ( nadD )
GO:0016740; transferase activity ( nadD )
GO:0016779; nucleotidyltransferase activity ( nadD )
GO:0019363; pyridine nucleotide biosynthetic process ( nadD )
 PID 1786858  
 EC number
  (KEGG Pathway)
 
2.7.7.18  
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) NADD_ECOLI ( P52085 )
    -  Protein name Nicotinate-nucleotide adenylyltransferase  
    -  Synonyms EC 2.7.7.18, Deamido- NAD(+) pyrophosphorylase, Deamido-NAD(+) diphosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase  
    -  Gene name Name=nadD; OrderedLocusNames=b0639, SF0642, S0664;  

 Linear View (Whole Mode)
View Location
   660.0  –  685.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP nadD (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of E. Coli Nicotinic Acid Mononucleotide Adenylyltransferase  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase) (Deamido-NAD(+) diphosphorylase) (Nicotinate mononucleotide adenylyltransferase) (NaMN adenylyltransferase)  
         PSI-BLAST Probable nicotinate-nucleotide adenylyltransferase
    nr     (database updated : 2007.02.20 )
         BLAST nicotinic acid mononucleotide adenyltransferase [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE     

Other Cross-Reference
    COG COG1057H 
    EcoCyc nadD 

Sequences
Amino acid
FASTA format
0001 MKSLQALFGG TFDPVHYGHL KPVETLANLI GLTRVTIIPN NVPPHRPQPE ANSVQRKHML ELAIADKPLF 
0071 TLDERELKRN APSYTAQTLK EWRQEQGPDV PLAFIIGQDS LLTFPTWYEY ETILDNAHLI VCRRPGYPLE 
0141 MAQPQYQQWL EDHLTHNPED LHLQPAGKIY LAETPWFNIS ATIIRERLQN GESCEDLLPE PVLTYINQQG 
0211 LYR

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ctcaaacaag attacggtca gtcagtgtgg 
-070 gcagagctgg aagggttatc tcttctgttg tgccataaac ccctggcgga cgtatttatc gacggttgat 
0001 atgaaatctt tacaggctct gtttggcggc acctttgatc cggtgcacta tggtcatcta aaacccgtgg 
0071 aaacgctggc gaatttgatt ggtctgacgc gggtcacaat catccctaat aatgttcctc cgcatcgtcc 
0141 ccagccggaa gcgaacagcg tgcagcgtaa acacatgctt gaactggcga ttgccgacaa gccattattt 
0211 actcttgatg aacgcgagct aaagcgcaat gccccctctt acactgcgca aacactgaaa gagtggcggc 
0281 aggaacaagg accggacgtg ccgctggcgt ttattattgg tcaggattca ctgctgacct ttccgacctg 
0351 gtacgaatac gaaacgatac tcgacaatgc acatttgatc gtctgtcggc gtccaggtta cccacttgaa 
0421 atggcgcaac cgcaatacca gcaatggctg gaagatcatt tgacacataa cccggaagat cttcaccttc 
0491 agcctgccgg taaaatttat ctggctgaaa cgccgtggtt taacatctcg gcgaccatca tccgcgaacg 
0561 tttgcaaaac ggtgaatcat gtgaggattt attgccggaa ccggtactga cttacattaa ccaacaaggc 
0631 ttgtatcgct gatacctgtc gttacggagg gcatgatgcg actgtggtta attcgtcatg gtgaaacgca 
0701 agcgaatatc gatggtcttt acagcggtca tgcgcccacc cc