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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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|
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Deletion
|
OCR45,46-3
(D)
,
OCR46
(D)
,
OCR46-7
(D)
|
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
lipB
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Related strains
|
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Strains Search
|
Search strains by gene name:
lipB
Search strains by all related name:
lipB b0630 cde ECK0623 JW5089
|
General information (Go to Linear View: )
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Gene Name
|
lipB
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Alternative name
|
b0630,cde,ECK0623,JW5089
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Location, Length
|
660,860 - 661,501
(
-
)
;
14.24
min
;
642
(bp) ,
213
(aa)
|
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Product
|
octanoyltransferase; octanoyl-[ACP]:protein N-octanoyltransferase
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Operon Name
|
ybeD-lipB
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Note
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protein of lipoate biosynthesis; GO_process: GO:0009107 - lipoate biosynthetic process
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Function
|
enzyme; Biosynthesis of cofactors, carriers: Lipoate
|
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Gene Ontology
|
GO:0003824
;
catalytic activity ( lipB )
GO:0005737
;
cytoplasm ( lipB )
GO:0006464
;
protein modification process ( lipB )
GO:0008415
;
acyltransferase activity ( lipB )
GO:0009107
;
lipoate biosynthetic process ( lipB )
GO:0016740
;
transferase activity ( lipB )
GO:0033819
;
lipoyl(octanoyl) transferase activity ( lipB )
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PID
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87081767
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EC number
(KEGG Pathway)
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2.3.1.-
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
LIPB_ECOLI
(
P60720
;
P30976; P77684; Q8XBQ2
)
|
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- Protein name
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Lipoyltransferase
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- Synonyms
|
EC 2.3.1.-, Lipoyl-[acyl-carrier protein]-protein -N-lipoyltransferase, Lipoate-protein ligase B
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- Gene name
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Name=lipB; OrderedLocusNames=b0630;
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MMBR References
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J Bacteriol. 1995;177:1-10
Lipoic acid metabolism in Escherichia coli: the lplA and lipB genes define redundant pathways for ligation of lipoyl groups to apoprotein.
Morris, T. W., K. E. Reed, and J. E. Cronan, Jr.
|
J Bacteriol. 1993;175:1325-1336
Lipoic acid metabolism in Escherichia coli: sequencing and functional characterization of the lipA and lipB genes.
Reed, K. E., and J. E. Cronan, Jr.
|
J Bacteriol. 1980;143(2):569-81.
Defective and plaque-forming lambda transducing bacteriophage carrying penicillin-binding protein-cell shape genes: genetic and physical mapping and identification of gene products from the lip-dacA-rodA-pbpA-leuS region of the Escherichia coli chromosome.
Spratt BG, Boyd A, Stoker N.
(
6451612
)
|
J Bacteriol. 1991;173(20):6411-20.
Lipoic acid metabolism in Escherichia coli: isolation of null mutants defective in lipoic acid biosynthesis, molecular cloning and characterization of the E. coli lip locus, and identification of the lipoylated protein of the glycine cleavage system.
Vanden Boom TJ, Reed KE, Cronan JE Jr.
(
1655709
)
|
J Bacteriol. 1991;173(17):5258-9.
Locations of the lip, poxB, and ilvBN genes on the physical map of Escherichia coli.
Chang YY, Cronan JE Jr, Li SJ, Reed K, Vanden Boom T, Wang AY.
(
1832150
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MYQDKILVRQ LGLQPYEPIS QAMHEFTDTR DDSTLDEIWL VEHYPVFTQG QAGKAEHILM PGDIPVIQSD
0071 RGGQVTYHGP GQQVMYVLLN LKRRKLGVRE LVTLLEQTVV NTLAELGIEA HPRADAPGVY VGEKKICSLG
0141 LRIRRGCSFH GLALNVNMDL SPFLRINPCG YAGMEMAKIS QWKPEATTNN IAPRLLENIL ALLNNPDFEY
0211 ITA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ctcgcttctc cgttacccgg ctcctggtcg
-070 ggtaactccc ctctcctcgc tgtgatatac ttttccccca cttttactca ttctccacgg agatgccgtt
0001 ttgtatcagg ataaaattct tgtccgccag ctcggtcttc agccttacga gccaatctcc caggctatgc
0071 atgaattcac cgatacccgc gatgatagta cccttgatga aatctggctg gtcgagcact atccggtatt
0141 cacccaaggt caggcaggaa aagcggagca cattttaatg ccgggtgata ttccggtgat ccagagcgat
0211 cgcggtgggc aggtgactta tcacgggccg gggcaacagg tgatgtatgt gttgcttaac ctgaaacgcc
0281 gtaaactcgg tgtgcgtgaa ctggtgacct tgcttgagca aacagtggtg aataccctgg ctgaactggg
0351 tatagaagcg catcctcggg ctgacgcgcc aggtgtctat gttggggaaa agaaaatttg ctcactgggt
0421 ttacgtattc gacgcggttg ttcattccac ggtctggcat taaacgtcaa tatggatctt tcaccatttt
0491 tacgtattaa tccttgtggg tatgccggaa tggaaatggc taaaatatca caatggaaac ccgaagcgac
0561 gactaataat attgctccac gtttactgga aaatatttta gcgctactaa acaatccgga cttcgaatat
0631 attaccgctt aattccatac atcaatggcc caatttacac tgggtcatta ctcataatat ctgctaatgc
0701 tttacatctc cttcgcgttt gtatattttc tttatcactt gc
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