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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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DE(ompT-fepC)266
,
OCR44,45-2 (LD 12-1_P/O)
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
pheP
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Related strains
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Strains Search
|
Search strains by gene name:
pheP
Search strains by all related name:
pheP b0576 ECK0568 JW0565
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General information (Go to Linear View: )
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Gene Name
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pheP
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Alternative name
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b0576,ECK0568,JW0565
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Location, Length
|
601,182 - 602,558
(
+
)
;
12.96
min
;
1377
(bp) ,
458
(aa)
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Product
|
phenylalanine transporter
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Operon Name
|
pheP
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Note
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phenylalanine-specific transport system; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009094 - L-phenylalanine biosynthetic process; GO_process: GO:0009063 - cellular amino acid catabolic process
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Function
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transport; Transport of small molecules: Amino acids, amines
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Gene Ontology
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GO:0005886
;
plasma membrane ( pheP )
GO:0006810
;
transport ( pheP )
GO:0006865
;
amino acid transport ( pheP )
GO:0015171
;
amino acid transmembrane transporter activity ( pheP )
GO:0016020
;
membrane ( pheP )
GO:0016021
;
integral to membrane ( pheP )
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PID
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1786789
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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PHEP_ECOLI
(
P24207
;
P77090
)
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- Protein name
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Phenylalanine-specific permease.
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- Synonyms
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- Gene name
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Name=pheP; OrderedLocusNames=b0576;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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pheP
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Phenylalanine-specific permease
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PSI-BLAST
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High-affinity glutamine permease
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nr
(database updated :
2007.02.20
)
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BLAST
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phenylalanine transporter [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
AMINO_ACID_PERMEASE
FKBP_PPIASE_1
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MMBR References
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J Bacteriol. 1993;175:7500-7504
Site-directed mutagenesis reveals the importance of conserved charged residues for the transport activity of the PheP permease of Escherichia coli.
Pi, J., P. J. Wookey, and A. J. Pittard.
|
J Bacteriol. 1980;143(1):1-7.
Isolation and characterization of an Escherichia coli K-12 mutant defective in tyrosine- and phenylalanine-specific transport systems.
Whipp MJ, Halsall DM, Pittard AJ.
(
6995422
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKNASTVSED TASNQEPTLH RGLHNRHIQL IALGGAIGTG LFLGIGPAIQ MAGPAVLLGY GVAGIIAFLI
0071 MRQLGEMVVE EPVSGSFAHF AYKYWGPFAG FLSGWNYWVM FVLVGMAELT AAGIYMQYWF PDVPTWIWAA
0141 AFFIIINAVN LVNVRLYGET EFWFALIKVL AIIGMIGFGL WLLFSGHGGE KASIDNLWRY GGFFATGWNG
0211 LILSLAVIMF SFGGLELIGI TAAEARDPEK SIPKAVNQVV YRILLFYIGS LVVLLALYPW VEVKSNSSPF
0281 VMIFHNLDSN VVASALNFVI LVASLSVYNS GVYSNSRMLF GLSVQGNAPK FLTRVSRRGV PINSLMLSGA
0351 ITSLVVLINY LLPQKAFGLL MALVVATLLL NWIMICLAHL RFRAAMRRQG RETQFKALLY PFGNYLCIAF
0421 LGMILLLMCT MDDMRLSAIL LPVWIVFLFM AFKTLRRK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AGCAGGATAC CCCGTTTAAC CGTGTGGATT
-070 GTGTCTTGCG ACGATGGGCA CTAAATGTTA AAAGGTGCCC CTCAACAAAA AAGACACACA GGGGAAAGGC
0001 gtgaaaaacg cgtcaaccgt atcggaagat actgcgtcga atcaagagcc gacgcttcat cgcggattac
0071 ataaccgtca tattcaactg attgcgttgg gtggcgcaat tggtactggt ctgtttcttg gcattggccc
0141 ggcgattcag atggcgggtc cggctgtatt gctgggctac ggcgtcgccg ggatcatcgc tttcctgatt
0211 atgcgccagc ttggcgaaat ggtggttgag gagccggtat ccggttcatt tgcccacttt gcctataaat
0281 actggggacc gtttgcgggc ttcctctctg gctggaacta ctgggtaatg ttcgtgctgg tgggaatggc
0351 agagctgacc gctgcgggca tctatatgca gtactggttc ccggatgttc caacgtggat ttgggctgcc
0421 gccttcttta ttatcatcaa cgccgttaac ctggtgaacg tgcgcttata tggcgaaacc gagttctggt
0491 ttgcgttgat taaagtgctg gcaatcatcg gtatgatcgg ctttggcctg tggctgctgt tttctggtca
0561 cggcggcgag aaagccagta tcgacaacct ctggcgctac ggtggtttct tcgccaccgg ctggaatggg
0631 ctgattttgt cgctggcggt aattatgttc tccttcggcg gtctggagct gattgggatt actgccgctg
0701 aagcgcgcga tccggaaaaa agcattccaa aagcggtaaa tcaggtggtg tatcgcatcc tgctgtttta
0771 catcggttca ctggtggttt tactggcgct ctatccgtgg gtggaagtga aatccaacag tagcccgttt
0841 gtgatgattt tccataatct cgacagcaac gtggtagctt ctgcgctgaa cttcgtcatt ctggtagcat
0911 cgctgtcagt gtataacagc ggggtttact ctaacagccg catgctgttt ggcctttctg tgcagggtaa
0981 tgcgccgaag tttttgactc gcgtcagccg tcgcggtgtg ccgattaact cgctgatgct ttccggagcg
1051 atcacttcgc tggtggtgtt aatcaactat ctgctgccgc aaaaagcgtt tggtctgctg atggcgctgg
1121 tggtagcaac gctgctgttg aactggatta tgatctgtct ggcgcatctg cgttttcgtg cagcgatgcg
1191 acgtcagggg cgtgaaacac agtttaaggc gctgctctat ccgttcggca actatctctg cattgccttc
1261 ctcggcatga ttttgctgct gatgtgcacg atggatgata tgcgcttgtc agcgatcctg ctgccggtgt
1331 ggattgtatt cctgtttatg gcatttaaaa cgctgcgtcg gaaataaGGC ATTCACGCTA CATCCGACAA
1401 AACGATGTCA ACCATCCGAA ACCGCTCTCA TCCATTCGAT GAGAGCGGTT TTTTTAATTA CTGCTTAAAT
1471 GCACCCG
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