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PEC Original Annotations
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Essentiality
|
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Class
|
non-essential
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References (PMID)
|
|
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Deletion
|
28
(LD)
,
OCR42,43-3 (LD 28B_CRS)
(D)
,
OCR42,43-4 (LD 28B_P/O)
(D)
,
OCR43
(D)
|
|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
fdrA
|
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Related strains
|
|
Strains Search
|
Search strains by gene name:
fdrA
Search strains by all related name:
fdrA b0518 ECK0511 JW0506 o555 ylbD
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General information (Go to Linear View: )
|
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Gene Name
|
fdrA
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Alternative name
|
b0518,ECK0511,JW0506,o555,ylbD
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Location, Length
|
545,904 - 547,571
(
+
)
;
11.77
min
;
1668
(bp) ,
555
(aa)
|
|
Product
|
multicopy suppressor of dominant negative ftsH mutations; predicted acyl-CoA synthetase with NAD(P)-binding Rossmann-fold domain
|
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Operon Name
|
fdrA-ylbE_1E_2F-ybcF
|
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Note
|
involved in protein transport; multicopy suppressor of dominant negative ftsH mutants; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
|
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Function
|
transport; Protein, peptide secretion
|
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Gene Ontology
|
GO:0003824
;
catalytic activity ( fdrA )
GO:0005488
;
binding ( fdrA )
GO:0005886
;
plasma membrane ( fdrA )
GO:0008152
;
metabolic process ( fdrA )
GO:0016020
;
membrane ( fdrA )
GO:0016021
;
integral to membrane ( fdrA )
|
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PID
|
1786729
|
EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
FDRA_ECOLI
(
Q47208
)
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- Protein name
|
Protein fdrA.
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- Synonyms
|
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- Gene name
|
Name=fdrA; OrderedLocusNames=b0518;
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Homology Analysis
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BLAST
|
|
Bacteria
|
|
GTOP
|
fdrA
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
|
Chain A, Crystal Structure Of Ph0766 From Pyrococcus Horikoshii Ot3
|
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SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Protein fdrA
|
|
PSI-BLAST
|
Protein fdrA
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
membrane protein FdrA [Escherichia coli K12]
|
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
GLYCOSAMINOGLYCAN
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
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MMBR References
|
Mol Gen Genet. 1995;249(2):202-8.
A new Escherichia coli gene, fdrA, identified by suppression analysis of dominant negative FtsH mutations.
Akiyama Y, Ito K.
(
7500942
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MIHAFIKKGC FQDSVSLMII SRKLSESENV DDVSVMMGTP ANKALLDTTG FWHDDFNNAT PNDICVAIRS
0071 EAADAGIAQA IMQQLEEALK QLAQGSGSSQ ALTQVRRWDS ACQKLPDANL ALISVAGEYA AELANQALDR
0141 NLNVMMFSDN VTLEDEIQLK TRAREKGLLV MGPDCGTSMI AGTPLAFANV MPEGNIGVIG ASGTGIQELC
0211 SQIALAGEGI THAIGLGGRD LSREVGGISA LTALEMLSAD EKSEVLAFVS KPPAEAVRLK IVNAMKATGK
0281 PTVALFLGYT PAVARDENVW FASSLDEAAR LACLLSRVTA RRNAIAPVSS GFICGLYTGG TLAAEAAGLL
0351 AGHLGVEADD THQHGMMLDA DSHQIIDLGD DFYTVGRPHP MIDPTLRNQL IADLGAKPQV RVLLLDVVIG
0421 FGATADPAAS LVSAWQKACA ARLDNQPLYA IATVTGTERD PQCRSQQIAT LEDAGIAVVS SLPEATLLAA
0491 ALIHPLSPAA QQHTPSLLEN VAVINIGLRS FALELQSASK PVVHYQWSPV AGGNKKLARL LERLQ
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TGATATTCAT CACCTTATTT ACTCGTTGTC
-070 ATCGATACCG TAATCGCCAC ATTAACACTG CTCGTGCAAT TGCCATGGGT GCAATTTTTA AGGAGTTGTT
0001 atgatccacg cctttattaa aaaagggtgt tttcaggatt cggtcagttt aatgattatt tcacgaaaac
0071 tcagcgaatc agaaaatgtt gatgatgttt ccgtaatgat gggtacgccc gccaataaag cgttattaga
0141 taccacaggt ttctggcatg acgattttaa taacgccacg ccgaacgata tttgcgtggc aattcgtagc
0211 gaagcggcgg atgcggggat cgcgcaggcg attatgcagc agcttgaaga ggcgctaaaa caactggcgc
0281 aggggtcagg cagcagccag gcgttgacgc aggtgcgtcg ctgggacagt gcctgtcaga aattacccga
0351 tgccaatctg gcgctgattt cagtggctgg cgagtatgcg gcggagctgg caaaccaggc gctggatcgc
0421 aacctcaacg tgatgatgtt ctccgataac gtcacgctgg aagatgaaat ccaacttaaa acccgcgcgc
0491 gggaaaaagg cttgctggtg atggggccgg actgcggtac gtcgatgatt gccggcacac cgctggcttt
0561 tgctaacgtg atgccggaag gcaatattgg cgtcattggc gcttccggta ccgggattca ggagctgtgt
0631 tcgcagattg cgctggcagg ggagggaatt actcacgcga ttggccttgg cgggcgcgac ctcagccgtg
0701 aagtgggcgg catcagtgcg ctaacagcgc tggaaatgct cagtgcagac gagaaaagcg aagtgctggc
0771 atttgtttca aaaccacctg ccgaagctgt gcgtctgaaa attgttaatg ccatgaaagc aaccggcaaa
0841 ccgacggtgg cgctgttttt aggttatacc ccggcggtgg cccgcgacga gaatgtctgg tttgcctcct
0911 cgctggatga ggccgcacgc ctggcttgcc tgctttcacg cgtcacggcg cgacgtaacg caatagcgcc
0981 tgtcagcagc ggatttattt gcggtttgta taccggcggt acgctggctg ccgaagcggc gggattactt
1051 gccggacacc ttggcgtgga agccgacgat acccatcaac atggcatgat gctggacgcc gatagccacc
1121 agattattga cctcggcgat gatttctaca ccgtcgggcg tccccatccg atgatcgacc caaccttacg
1191 caaccagtta attgccgatc tcggcgctaa accgcaagtg cgcgtgttgc tgcttgatgt cgtgattggc
1261 ttcggtgcga ccgccgatcc tgccgcctcg ctggtgagcg cctggcaaaa agcctgtgcc gcgcgtttag
1331 ataatcaacc actgtatgcc attgccacgg tgacaggcac tgaacgtgac ccgcaatgcc gctcgcagca
1401 aatcgccacg ctggaagatg cggggattgc ggtcgtgagt tcgctaccgg aagccacctt gctggcggca
1471 gcgttaattc atccgctctc gcctgccgca cagcaacaca caccgtcatt actggaaaac gtcgccgtga
1541 ttaacatcgg attacgcagc tttgcgctgg agctacaaag cgccagcaaa ccggttgtgc attaccaatg
1611 gtcgccagtc gccggtggca ataaaaaact ggctcgttta ttagaacgtt tgcaataaGG GGTTCCCATG
1681 TTTACATCAG TGGCGCAAGC CAATGCTGCG GTTATCGAAC AAATTCGTCG CGCTCGTCCA CACTGGCTGG
1751 ATGTGCAACC GGCTTCTT
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