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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Mol Microbiol. 1995;16(1):45-55.
Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli.
Ma D, Cook DN, Alberti M, Pon NG, Nikaido H, Hearst JE.
(
7651136
)
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Deletion
|
OCR41
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
acrR
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Related strains
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Strains Search
|
Search strains by gene name:
acrR
Search strains by all related name:
acrR b0464 ECK0458 JW0453 ybaH
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General information (Go to Linear View: )
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Gene Name
|
acrR
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Alternative name
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b0464,ECK0458,JW0453,ybaH
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Location, Length
|
484,985 - 485,632
(
+
)
;
10.45
min
;
648
(bp) ,
215
(aa)
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Product
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DNA-binding transcriptional repressor
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Operon Name
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acrR
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Note
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acrAB operon repressor; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0006350 - transcription; GO_process: GO:0042493 - response to drug
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Function
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regulator; Drug/analog sensitivity
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Gene Ontology
|
GO:0003677
;
DNA binding ( acrR )
GO:0003700
;
transcription factor activity ( acrR )
GO:0005515
;
protein binding ( acrR )
GO:0006350
;
transcription ( acrR )
GO:0006355
;
regulation of transcription, DNA-dependent ( acrR )
GO:0030528
;
transcription regulator activity ( acrR )
GO:0045449
;
regulation of transcription ( acrR )
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PID
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1786669
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
ACRR_ECOLI
(
P34000
)
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- Protein name
|
HTH-type transcriptional regulator acrR
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- Synonyms
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Potential acrAB operon repressor
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- Gene name
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Name=acrR; OrderedLocusNames=b0464, c0582, SF0409, S0416;
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MMBR References
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Mol Microbiol. 1996;19(1):101-12.
The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals.
Ma D, Alberti M, Lynch C, Nikaido H, Hearst JE.
(
8821940
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MARKTKQEAQ ETRQHILDVA LRLFSQQGVS STSLGEIAKA AGVTRGAIYW HFKDKSDLFS EIWELSESNI
0071 GELELEYQAK FPGDPLSVLR EILIHVLEST VTEERRRLLM EIIFHKCEFV GEMAVVQQAQ RNLCLESYDR
0141 IEQTLKHCIE AKMLPADLMT RRAAIIMRGY ISGLMENWLF APQSFDLKKE ARDYVAILLE MYLLCPTLRN
0211 PATNE
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AAAAGTTAAT AAACCCATTG CTGCGTTTAT
-070 ATTATCGTCG TGCTATGGTA CATACATTCA CAAATGTATG TAAATCTAAC GCCTGTAAAT TCACGAACAT
0001 atggcacgaa aaaccaaaca agaagcgcaa gaaacgcgcc aacacatcct cgatgtggct ctacgtcttt
0071 tctcacagca gggggtatca tccacctcgc tgggcgagat tgcaaaagca gctggcgtta cgcgcggtgc
0141 aatctactgg cattttaaag acaagtcgga tttgttcagt gagatctggg aactgtcaga atccaatatt
0211 ggtgaactag agcttgagta tcaggcaaaa ttccctggcg atccactctc agtattaaga gagatattaa
0281 ttcatgttct tgaatccacg gtgacagaag aacggcgtcg attattgatg gagattatat tccacaaatg
0351 cgaatttgtc ggagaaatgg ctgttgtgca acaggcacaa cgtaatctct gtctggaaag ttatgaccgt
0421 atagaacaaa cgttaaaaca ttgtattgaa gcgaaaatgt tgcctgcgga tttaatgacg cgtcgcgcag
0491 caattattat gcgcggctat atttccggcc tgatggaaaa ctggctcttt gccccgcaat cttttgatct
0561 taaaaaagaa gcccgcgatt acgttgccat cttactggag atgtatctcc tgtgccccac gcttcgtaat
0631 cctgccacta acgaataaCC CTGAATCTGA CTCCAGGATT TTTCCTGGAC ATTTTCGTCG TTGCTATTCT
0701 GGTTCACTGC GTCGTGATAT TCTTGCGGTT TGACTTTTTC AGGTCGTT
|
