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PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
|
|
Deletion
|
DE(deoD-arcA)253
,
OCR26,27-4
(D)
,
OCR26,27-5
(D)
,
OCR27-7
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
serB
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
serB
Search strains by all related name:
serB b4388 ECK4380 JW4351
|
General information (Go to Linear View: )
|
|
Gene Name
|
serB
|
|
Alternative name
|
b4388,ECK4380,JW4351
|
|
Location, Length
|
4,622,918 - 4,623,886
(
+
)
;
99.64
min
;
969
(bp) ,
322
(aa)
|
|
Product
|
3-phosphoserine phosphatase
|
|
Operon Name
|
serB-radA-nadR
|
|
Note
|
GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006545 - glycine biosynthetic process; GO_process: GO:0006564 - L-serine biosynthetic process
|
|
Function
|
enzyme; Amino acid biosynthesis: Serine
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( serB )
GO:0004647
;
phosphoserine phosphatase activity ( serB )
GO:0005515
;
protein binding ( serB )
GO:0005524
;
ATP binding ( serB )
GO:0006564
;
L-serine biosynthetic process ( serB )
GO:0006810
;
transport ( serB )
GO:0008152
;
metabolic process ( serB )
GO:0008652
;
amino acid biosynthetic process ( serB )
GO:0015662
;
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism ( serB )
GO:0016020
;
membrane ( serB )
GO:0016787
;
hydrolase activity ( serB )
GO:0016791
;
phosphoric monoester hydrolase activity ( serB )
|
|
PID
|
1790849
|
EC number
(KEGG Pathway)
|
3.1.3.3
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
SERB_ECOLI
(
P06862
)
|
|
- Protein name
|
Phosphoserine phosphatase
|
|
- Synonyms
|
EC 3.1.3.3, PSP, O-phosphoserine phosphohydrolase, PSPase
|
|
- Gene name
|
Name=serB; OrderedLocusNames=b4388, z5989, ECs5346, SF4420, S4691;
|
|
MMBR References
|
Mol Gen Genet. 1979;176(3):361-8.
Cloning the trpR gene.
Roeder W, Somerville RL.
(
160491
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MPNITWCDLP EDVSLWPGLP LSLSGDEVMP LDYHAGRSGW LLYGRGLDKQ RLTQYQSKLG AAMVIVAAWC
0071 VEDYQVIRLA GSLTARATRL AHEAQLDVAP LGKIPHLRTP GLLVMDMDST AIQIECIDEI AKLAGTGEMV
0141 AEVTERAMRG ELDFTASLRS RVATLKGADA NILQQVRENL PLMPGLTQLV LKLETLGWKV AIASGGFTFF
0211 AEYLRDKLRL TAVVANELEI MDGKFTGNVI GDIVDAQYKA KTLTRLAQEY EIPLAQTVAI GDGANDLPMI
0281 KAAGLGIAYH AKPKVNEKAE VTIRHADLMG VFCILSGSLN QK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ACCCTTTGAA AATTTGAGAC TTAATGTTGC
-070 CAGAAGCAAT GGATACAAGG TAGCCTCATG CGTTATTTTC CCTGCTTCGA ACGATTTTAC AGGAGCCTTA
0001 atgcctaaca ttacctggtg cgacctgcct gaagatgtct ctttatggcc gggtctgcct ctttcattaa
0071 gtggtgatga agtgatgcca ctggattacc acgcaggtcg tagcggctgg ctgctgtatg gtcgtgggct
0141 ggataaacaa cgtctgaccc aataccagag caaactgggt gcggcgatgg tgattgttgc cgcctggtgc
0211 gtggaagatt atcaggtgat tcgtctggca ggttcactca ccgcacgggc tacacgcctg gcccacgaag
0281 cgcagctgga tgtcgccccg ctggggaaaa tcccgcacct gcgcacgccg ggtttgctgg tgatggatat
0351 ggactccacc gccatccaga ttgaatgtat tgatgaaatt gccaaactgg ccggaacggg cgagatggtg
0421 gcggaagtaa ccgaacgggc gatgcgcggc gaactcgatt ttaccgccag cctgcgcagc cgtgtggcga
0491 cgctgaaagg cgctgacgcc aatattctgc aacaggtgcg tgaaaatctg ccgctgatgc caggcttaac
0561 gcaactggtg ctcaagctgg aaacgctggg ctggaaagtg gcgattgcct ccggcggctt tactttcttt
0631 gctgaatacc tgcgcgacaa gctgcgcctg accgccgtgg tagccaatga actggagatc atggacggta
0701 aatttaccgg caatgtgatc ggcgacatcg tagacgcgca gtacaaagcg aaaactctga ctcgcctcgc
0771 gcaggagtat gaaatcccgc tggcgcagac cgtggcgatt ggcgatggag ccaatgacct gccgatgatc
0841 aaagcggcag ggctggggat tgcctaccat gccaagccaa aagtgaatga aaaggcggaa gtcaccatcc
0911 gtcacgctga cctgatgggg gtattctgca tcctctcagg cagcctgaat cagaagtaaT TGCTCGCCCG
0981 CCATCCTGCG GGCGGCACAG CATTAACGAG GTACACCGTG GCAAAAGCTC CAAAACGCGC CTTTGTTTGT
1051 AATGAATGCG GGGCCGATT
|
