MG1655
W3110
Search for
Japanese | English
Gene Report : deoB
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCR26 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  deoB
Related strains
     Strains Search Search strains by gene name:  deoB   Search strains by all related name:  deoB b4383 drm ECK4375 JW4346 thyR tlr trl

General information  (Go to Linear View:)
 Gene Name deoB  
 Alternative name b4383,drm,ECK4375,JW4346,thyR,tlr,trl  
 Location, Length 4,617,626 - 4,618,849 (  +  ) ;   99.52 min ; 1224 (bp) ,   407 (aa) Go to Linear View
 Product phosphopentomutase  
 Operon Name deoCABD  
 Note GO_process: GO:0015949 - nucleobase, nucleoside and nucleotide interconversion  
 Function enzyme; Salvage of nucleosides and nucleotides  
 Gene Ontology GO:0000287; magnesium ion binding ( deoB )
GO:0003824; catalytic activity ( deoB )
GO:0005737; cytoplasm ( deoB )
GO:0008973; phosphopentomutase activity ( deoB )
GO:0009117; nucleotide metabolic process ( deoB )
GO:0009166; nucleotide catabolic process ( deoB )
GO:0009264; deoxyribonucleotide catabolic process ( deoB )
GO:0016853; isomerase activity ( deoB )
GO:0030145; manganese ion binding ( deoB )
GO:0043094; metabolic compound salvage ( deoB )
GO:0046872; metal ion binding ( deoB )
 PID 1790843  
 EC number
  (KEGG Pathway)
 
5.4.2.7  
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) DEOC_ECOLI ( P00882 )
    -  Protein name Deoxyribose-phosphate aldolase  
    -  Synonyms EC 4.1.2.4, Phosphodeoxyriboaldolase, Deoxyriboaldolase, DERA  
    -  Gene name Name=deoC; Synonyms=dra, thyR; OrderedLocusNames=b4381, c5465;  

 Linear View (Whole Mode)
View Location
   4605.0  –  4630.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP deoB (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of Putative Phosphopentomutase From Streptococcus Mutans  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Phosphopentomutase (Phosphodeoxyribomutase)  
         PSI-BLAST Phosphopentomutase (Phosphodeoxyribomutase)
    nr     (database updated : 2007.02.20 )
         BLAST phosphopentomutase [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    AMIDATION     

Other Cross-Reference
    COG COG1015G 
    EcoCyc deoB 

MMBR References
Gene. 1982;17(3):291-8.
The cloning of the Escherichia coli K-12 deoxyribonucleoside operon.
Fischer M, Short SA. ( 6286410 )
Mol Gen Genet. 1969;104(4):351-9.
A map of four genes specifying enzymes involved in catabolism of nucleosides and deoxynucleosides in Escherichia coli.
Ahmad SI, Pritchard RH. ( 4904508 )
J Bacteriol. 1968;96(2):501-14.
Characteristics of the deo operon: role in thymine utilization and sensitivity to deoxyribonucleosides.
Lomax MS, Greenberg GR. ( 4877128 )
Mol Gen Genet. 1979;176(3):361-8.
Cloning the trpR gene.
Roeder W, Somerville RL. ( 160491 )
Eur J Biochem. 1982;125:561-566
The primary structure of Escherichia coli K12 2-deoxyribose 5-phosphate aldolase. Nucleotide sequence of the deoC gene and the amino acid sequence of the enzyme.
Valentin-Hansen, P., F. Boetius, K. Hammer-Jespersen, and I. Svendsen.
Nucleic Acids Res. 1984;12:5211-5224
The internal regulated promoter of the deo operon of Escherichia coli K-12.
Valentin-Hansen, P., K. Hammer, E. L. Larsen, and I. Svendsen.
J Mol Biol. 1979;133(1):1-17.
Evidence for the existence of three promoters for the deo operon of Escherichia coli K12 in vitro.
Valentin-Hansen P, Hammer-Jespersen K, Buxton RS. ( 231107 )

Sequences
Amino acid
FASTA format
0001 MKRAFIMVLD SFGIGATEDA ERFGDVGADT LGHIAEACAK GEADNGRKGP LNLPNLTRLG LAKAHEGSTG 
0071 FIPAGMDGNA EVIGAYAWAH EMSSGKDTPS GHWEIAGVPV LFEWGYFSDH ENSFPQELLD KLVERANLPG 
0141 YLGNCHSSGT VILDQLGEEH MKTGKPIFYT SADSVFQIAC HEETFGLDKL YELCEIAREE LTNGGYNIGR 
0211 VIARPFIGDK AGNFQRTGNR HDLAVEPPAP TVLQKLVDEK HGQVVSVGKI ADIYANCGIT KKVKATGLDA 
0281 LFDATIKEMK EAGDNTIVFT NFVDFDSSWG HRRDVAGYAA GLELFDRRLP ELMSLLRDDD ILILTADHGC 
0351 DPTWTGTDHT REHIPVLVYG PKVKPGSLGH RETFADIGQT LAKYFGTSDM EYGKAMF

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             TAAAGCACCG GAAAGCACAC CAACTGTCTA 
-070 TCGCCGTATC AGCGAATAAC GGTATACTGA TCTGATCATT TAAATTTGAA GCACTGAGTA CGGAGAACAT 
0001 atgaaacgtg catttattat ggtgctggac tcattcggca tcggcgctac agaagatgca gaacgctttg 
0071 gtgacgtcgg ggctgacacc ctgggtcata tcgcagaagc ttgtgccaaa ggcgaagctg ataacggtcg 
0141 taaaggcccg ctcaatctgc caaatctgac ccgtctgggg ctggcgaaag cacacgaagg ttctaccggt 
0211 ttcattccgg cgggaatgga cggcaacgct gaagttatcg gcgcgtacgc atgggcgcac gaaatgtcat 
0281 ccggtaaaga taccccgtct ggtcactggg aaattgccgg tgtcccggtt ctgtttgagt ggggatattt 
0351 ctccgatcac gaaaacagct tcccgcaaga gctgctggat aaactggtcg aacgcgctaa tctgccgggt 
0421 tacctcggta actgccactc ttccggtacg gtcattctgg atcaactggg cgaagagcac atgaaaaccg 
0491 gcaagccgat tttctatacc tccgctgact ccgtgttcca gattgcctgc catgaagaaa ctttcggtct 
0561 ggataaactc tacgaactgt gcgaaatcgc ccgtgaagag ctgaccaacg gcggctacaa tatcggtcgt 
0631 gttatcgctc gtccgtttat cggcgacaaa gccggtaact tccagcgtac cggtaaccgt cacgacctgg 
0701 ctgttgagcc gccagcaccg accgtgctgc agaaactggt tgatgaaaaa cacggccagg tggtttctgt 
0771 cggtaaaatt gcggacatct acgccaactg cggtatcacc aaaaaagtga aagcgactgg cctggacgcg 
0841 ctgtttgacg ccaccatcaa agagatgaaa gaagcgggtg ataacaccat cgtcttcacc aacttcgttg 
0911 acttcgactc ttcctggggc caccgtcgcg acgtcgccgg ttatgccgcg ggtctggaac tgttcgaccg 
0981 ccgtctgccg gagctgatgt ctctgctgcg cgatgacgac atcctgatcc tcaccgctga ccacggttgc 
1051 gatccgacct ggaccggtac tgaccacacg cgtgaacaca ttccggtact ggtatatggc ccgaaagtaa 
1121 aaccgggctc actgggtcat cgtgaaacct tcgcggatat cggccagact ctggcaaaat attttggtac 
1191 ttctgatatg gaatatggca aagccatgtt ctgaTGGATT TGGGCGGAGC GTTGACTCCG CCTTTGTTAT 
1261 GTCACAAAAA GGATAAAACA ATGGCTACCC CACACATTAA TGCAGAAATG GGCGATTTCG CTGA