MG1655
W3110
Search for
Japanese | English
Gene Report : fhuF
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion OCR25 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fhuF
Related strains
     Strains Search Search strains by gene name:  fhuF   Search strains by all related name:  fhuF b4367 ECK4357 f262b JW4331 yjjS

General information  (Go to Linear View:)
 Gene Name fhuF  
 Alternative name b4367,ECK4357,f262b,JW4331,yjjS  
 Location, Length 4,602,898 - 4,603,686 (  -  ) ;   99.21 min ; 789 (bp) ,   262 (aa) Go to Linear View
 Product ferric iron reductase involved in ferric hydroximate transport  
 Operon Name fhuF  
 Note GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006457 - protein folding  
 Function  
 Gene Ontology GO:0005506 ; iron ion binding ( fhuF )
GO:0005737 ; cytoplasm ( fhuF )
GO:0005886 ; plasma membrane ( fhuF )
GO:0016020 ; membrane ( fhuF )
GO:0046872 ; metal ion binding ( fhuF )
GO:0051536 ; iron-sulfur cluster binding ( fhuF )
GO:0051537 ; 2 iron, 2 sulfur cluster binding ( fhuF )
 PID 1790829  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 3 more] )
  botton Entry name(Acc.no) FHUF_ECOLI ( P39405 )
    -  Protein name Ferric iron reductase protein fhuF.  
    -  Synonyms  
    -  Gene name Name=fhuF; OrderedLocusNames=b4367;  

 Linear View (Whole Mode)
View Location
   4590.0  –  4615.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fhuF (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
        PSI-BLAST  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Ferric iron reductase protein fhuF  
         PSI-BLAST Ferric iron reductase protein fhuF
    nr     (database updated : 2007.02.20 )
         BLAST ferric iron reductase involved in ferric hydroximate transport [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    PRENYLATION     

Other Cross-Reference
    COG COG4114R 
    EcoCyc fhuF 

MMBR References
Mol Gen Genet. 1987;210(1):135-9.
Selection procedure for deregulated iron transport mutants (fur) in Escherichia coli K 12: fur not only affects iron metabolism.
Hantke K. ( 3323834 )
Submitted for publication.
FhuF, an iron-regulated protein of Escherichia coli with a new type of [2FE-2S] center.
Mueller-Wriedt, K., B. F. Matzanke, V. Schoenemann, A. X. Trautwein, and K. Hantke.

Sequences
Amino acid
FASTA format
0001 MAYRSAPLYE DVIWRTHLQP QDPTLAQAVR ATIAKHREHL LEFIRLDEPA PLNAMTLAQW SSPNVLSSLL 
0071 AVYSDHIYRN QPMMIRENKP LISLWAQWYI GLMVPPLMLA LLTQEKALDV SPEHFHAEFH ETGRVACFWV 
0141 DVCEDKNATP HSPQHRMETL ISQALVPVVQ ALEATGEING KLIWSNTGYL INWYLTEMKQ LLGEATVESL 
0211 RHALFFEKTL TNGEDNPLWR TVVLRDGLLV RRTCCQRYRL PDVQQCGDCT LK

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             tgataatttt tatcatttgc aagccagata 
-070 aatcccttgc tatcgggtaa acctatcgct atgattagca atcattatca tttagattac tatcccgatt 
0001 atggcctatc gttccgcacc gctctatgaa gatgtcatct ggcgaacgca tctccagccg caggatccca 
0071 cgcttgcgca agccgtgcgg gcgacgatcg caaaacatcg tgaacatttg ctggagttta tccgcctgga 
0141 tgaacctgcc ccacttaacg ccatgacgct ggcgcaatgg tcatcaccga atgtgctaag ttctctgctg 
0211 gcggtctatt ccgatcatat ctatcgcaac caaccgatga tgatccgcga gaacaaaccg ctgatctcac 
0281 tatgggcaca atggtatatc ggcctgatgg tgccaccatt aatgctggcg ctactgacgc aggaaaaggc 
0351 attagatgtg tcgccggaac atttccatgc tgagtttcac gaaaccggac gcgtcgcctg tttctgggtc 
0421 gatgtgtgtg aagataaaaa cgcaacacca cattcgccgc agcatcgaat ggaaacgtta atcagccagg 
0491 cgctggttcc ggttgtgcaa gcactagaag cgaccggaga gatcaacggc aaacttatct ggagtaatac 
0561 cggttatttg atcaactggt atctcactga gatgaagcaa ctgctcggcg aggctactgt tgaatcgctg 
0631 cgccatgccc tcttttttga gaaaacgctc acgaacggtg aagataatcc actctggcgt accgtggtac 
0701 tgcgcgacgg cctgctggtg cgccgcactt gctgccagcg ttatcgctta ccggatgtgc agcaatgtgg 
0771 cgattgtacg ctgaaatgaa agcactgccg gggaagtaaa cccggcatca tgcggattaa tagggatgca 
0841 acacattact tgtttcgcaa tgccgcatac ataacagaat atctgcggc