|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Microbiol Mol Biol Rev. 1998;62(3):814-984
Linkage map of Escherichia coli K-12, edition 10: the traditional map.
Berlyn MK.
(
9729611
)
|
|
|
Deletion
|
OCR39
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
pgpA
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
pgpA
Search strains by all related name:
pgpA b0418 ECK0412 JW0408 o172 yajN
|
General information (Go to Linear View: )
|
|
Gene Name
|
pgpA
|
|
Alternative name
|
b0418,ECK0412,JW0408,o172,yajN
|
|
Location, Length
|
435,813 - 436,331
(
+
)
;
9.39
min
;
519
(bp) ,
172
(aa)
|
|
Product
|
phosphatidylglycerophosphatase A
|
|
Operon Name
|
nrdR-ribDE-nusB-thiL-pgpA
|
|
Note
|
phosphatidylglycerophosphatase; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0008654 - phospholipid biosynthetic process
|
|
Function
|
enzyme; Macromolecule synthesis, modification: Phospholipids
|
|
Gene Ontology
|
GO:0005886
;
plasma membrane ( pgpA )
GO:0006629
;
lipid metabolic process ( pgpA )
GO:0008962
;
phosphatidylglycerophosphatase activity ( pgpA )
GO:0009395
;
phospholipid catabolic process ( pgpA )
GO:0016020
;
membrane ( pgpA )
GO:0016021
;
integral to membrane ( pgpA )
GO:0016787
;
hydrolase activity ( pgpA )
|
|
PID
|
1786620
|
EC number
(KEGG Pathway)
|
3.1.3.27
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
PGPA_ECOLI
(
P18200
;
P77321
)
|
|
- Protein name
|
Phosphatidylglycerophosphatase A
|
|
- Synonyms
|
EC 3.1.3.27
|
|
- Gene name
|
Name=pgpA; OrderedLocusNames=b0418;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
pgpA
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Phosphatidylglycerophosphatase A
|
|
PSI-BLAST
|
Phosphatidylglycerophosphatase A
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
phosphatidylglycerophosphatase A [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
|
|
MMBR References
|
J Bacteriol. 1992;174:205-213
The pgpA and pgpB genes of Escherichia coli are not essential: evidence for a third phosphatidylglycerophosphate phosphatase.
Funk, C. R., L. Zimniak, and W. Dowhan.
|
J Bacteriol. 1988;170(11):5110-6.
Membrane-bound phosphatases in Escherichia coli: sequence of the pgpA gene.
Icho T.
(
2846510
)
|
J Bacteriol. 1983;153(2):722-30.
Multiple genes for membrane-bound phosphatases in Escherichia coli and their action on phospholipid precursors.
Icho T, Raetz CR.
(
6296050
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MTILPRHKDV AKSRLKMSNP WHLLAVGFGS GLSPIVPGTM GSLAAIPFWY LMTFLPWQLY SLVVMLGICI
0071 GVYLCHQTAK DMGVHDHGSI VWDEFIGMWI TLMALPTNDW QWVAAGFVIF RILDMWKPWP IRWFDRNVHG
0141 GMGIMIDDIV AGVISAGILY FIGHHWPLGI LS
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CTGGGCGTAC CGTTTACCTG TATCGGGCAA
-070 ATGACCGCCG ATATCGAAGG GCTTTGTTTT ATTCGTGACG GCGAACCTGT TACATTAGAC TGGAAAGGAT
0001 atgaccattt tgccacgcca taaagatgtc gcgaaaagtc gcctgaagat gagtaatccg tggcatctac
0071 ttgctgtcgg attcggaagt ggattaagcc cgatcgttcc tgggacgatg ggctcgctgg cagcgattcc
0141 gttctggtat ctgatgacct ttttgccctg gcagctctac tcgctggtgg tgatgctggg gatctgtatc
0211 ggcgtctatc tttgtcatca aacggcgaaa gacatgggtg tgcacgatca tggcagcatt gtctgggacg
0281 aatttattgg tatgtggatc acgctcatgg cgctgccgac caatgactgg cagtgggttg ccgccgggtt
0351 tgtgattttc cgtattctgg atatgtggaa gccgtggccg atccgctggt ttgatcgcaa tgtgcatggc
0421 ggcatgggga tcatgatcga cgatattgtc gccggggtga tttccgcagg catcctgtat tttatcggtc
0491 atcactggcc gctgggtatt ctgtcgtagT TGTGCACCGA TGCCTGATGT GACGCTTGTC ACGTCTCATC
0561 AGGCCTGGAC TCTTATTTAA ATCCTACGAC AGGATGCGGT TTATACGGCG TTTCCAGTT
|
