MG1655
W3110
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Gene Report : nrdR
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Bacteriol. 2007;189(14):5012-21
NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes.
Torrents E, Grinberg I, Gorovitz-Harris B, Lundstrom H, Borovok I, Aharonowitz Y, Sjoberg BM, Cohen G. ( 17496099 )
     Deletion OCR39 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  nrdR
Related strains
     Strains Search Search strains by gene name:  nrdR   Search strains by all related name:  nrdR b0413 ECK0407 JW0403 ribX ybaD

General information  (Go to Linear View:)
 Gene Name nrdR  
 Alternative name b0413,ECK0407,JW0403,ribX,ybaD  
 Location, Length 432,226 - 432,675 (  +  ) ;   9.32 min ; 450 (bp) ,   149 (aa) Go to Linear View
 Product hypothetical protein  
 Operon Name nrdR-ribDE-nusB-thiL-pgpA  
 Note  
 Function  
 Gene Ontology GO:0000166 ; nucleotide binding ( nrdR )
GO:0003677 ; DNA binding ( nrdR )
GO:0005524 ; ATP binding ( nrdR )
GO:0006350 ; transcription ( nrdR )
GO:0006355 ; regulation of transcription, DNA-dependent ( nrdR )
GO:0008270 ; zinc ion binding ( nrdR )
GO:0016564 ; transcription repressor activity ( nrdR )
GO:0046872 ; metal ion binding ( nrdR )
 PID 1786615  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) YBAD_ECOLI ( P25538 )
    -  Protein name Hypothetical UPF0168 protein ybaD.  
    -  Synonyms  
    -  Gene name Name=ybaD; OrderedLocusNames=b0413, c0523, z0514, ECs0466;  

 Linear View (Whole Mode)
View Location
   420.0  –  445.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP ybaD (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
        PSI-BLAST  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Transcriptional repressor nrdR  
         PSI-BLAST Transcriptional repressor nrdR
    nr     (database updated : 2007.02.20 )
         BLAST hypothetical protein Z0514 [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    EcoCyc nrdR 

Sequences
Amino acid
FASTA format
0001 MHCPFCFAVD TKVIDSRLVG EGSSVRRRRQ CLVCNERFTT FEVAELVMPR VVKSNDVREP FNEEKLRSGM 
0071 LRALEKRPVS SDDVEMAINH IKSQLRATGE REVPSKMIGN LVMEQLKKLD KVAYIRFASV YRSFEDIKEF 
0141 GEEIARLED

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             GCGAAAGCAT CGATCCTTTA TCTCAAAAGC 
-070 GTTGCGCCTT TGTTGTATCG TCAGTTCAGG GTAAAATAGA TTTCCGTTAA CCACCTGGTC AGGACGCCGT 
0001 atgcattgcc cattctgttt cgccgtggac actaaggtaa ttgactctcg tctcgtgggc gagggttcat 
0071 ccgtacgccg ccgtcggcag tgtctggtgt gtaatgaacg tttcaccacc tttgaagtgg cggagctggt 
0141 tatgccgcgt gttgtaaaaa gcaacgacgt gcgtgaaccg tttaatgaag agaaattgcg tagcggaatg 
0211 ctgcgggcgc tggaaaaacg tccggtgagt tccgatgacg tcgaaatggc aatcaatcat attaaatcgc 
0281 agctgcgcgc caccggtgag cgcgaagtgc cgagcaagat gattggcaat ctggtgatgg agcaattgaa 
0351 aaagctcgat aaagtcgcct atatccgttt tgcctctgtc taccgcagtt tcgaagatat caaagaattt 
0421 ggcgaagaga tcgcgcgcct ggaggactaa GCCGTGCAGG ACGAGTATTA CATGGCGCGG GCGCTAAAGC 
0491 TGGCGCAACG AGGACGTTTT ACCACGCATC CCAACCCGAA TGTCGGGTGC GTCATTGTCA