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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
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Deletion
|
OCR39
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
tsx
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|
Related strains
|
|
Strains Search
|
Search strains by gene name:
tsx
Search strains by all related name:
tsx b0411 ECK0405 JW0401 nupA T6rec
|
General information (Go to Linear View: )
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Gene Name
|
tsx
|
|
Alternative name
|
b0411,ECK0405,JW0401,nupA,T6rec
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|
Location, Length
|
430,353 - 431,237
(
-
)
;
9.28
min
;
885
(bp) ,
294
(aa)
|
|
Product
|
nucleoside channel, receptor of phage T6 and colicin K
|
|
Operon Name
|
tsx
|
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Note
|
nucleoside channel; receptor of phage T6 and colicin K; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0009279 - cell outer membrane; GO_process: GO:0015949 - nucleobase, nucleoside and nucleotide interconversion
|
|
Function
|
transport; Transport of small molecules: Nucleosides, purines, pyrimidines
|
|
Gene Ontology
|
GO:0005337
;
nucleoside transmembrane transporter activity ( tsx )
GO:0006810
;
transport ( tsx )
GO:0006811
;
ion transport ( tsx )
GO:0009279
;
cell outer membrane ( tsx )
GO:0009597
;
detection of virus ( tsx )
GO:0016020
;
membrane ( tsx )
GO:0016021
;
integral to membrane ( tsx )
GO:0019867
;
outer membrane ( tsx )
GO:0046718
;
entry of virus into host cell ( tsx )
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PID
|
1786612
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
TSX_ECOLI
(
P22786
)
|
|
- Protein name
|
Nucleoside-specific channel-forming protein tsx precursor.
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- Synonyms
|
|
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- Gene name
|
OrderedLocusNames=b0411, z0512, ECs0464, SF0348, S0356;
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
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GTOP
|
tsx
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Tsx Structure Complexed With Thymidine
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Nucleoside-specific channel-forming protein tsx precursor
|
|
PSI-BLAST
|
Nucleoside-specific channel-forming protein tsx precursor
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
TSX [Escherichia coli O157:H7 str. Sakai]
|
|
Pfam 28.0
(database updated :
2015-05
)
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Pfam
|
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PROSITE
|
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PROSITE
|
ASN_GLYCOSYLATION
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
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MMBR References
|
FEBS Lett. 1976;70(1):109-12.
Phage T6--colicin K receptor and nucleoside transport in Escherichia coli.
Hantke K.
(
791677
)
|
J Bacteriol. 1992;174(5):1709-10.
Alignment of genes from the 9-minute region (araJ to tsx) of the Escherichia coli K-12 linkage map to the physical map.
Lucht JM, Boos W, Bremer E.
(
1537816
)
|
Gene. 1990;96(1):59-65.
Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli.
Bremer E, Middendorf A, Martinussen J, Valentin-Hansen P.
(
2265760
)
|
J Bacteriol. 1988;170(1):108-16.
Double negative and positive control of tsx expression in Escherichia coli.
Bremer E, Gerlach P, Middendorf A.
(
2826388
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKKTLLAAGA VLALSSSFTV NAAENDKPQY LSDWWHQSVN VVGSYHTRFG PQIRNDTYLE YEAFAKKDWF
0071 DFYGYADAPV FFGGNSDAKG IWNHGSPLFM EIEPRFSIDK LTNTDLSFGP FKEWYFANNY IYDMGRNKDG
0141 RQSTWYMGLG TDIDTGLPMS LSMNVYAKYQ WQNYGAANEN EWDGYRFKIK YFVPITDLWG GQLSYIGFTN
0211 FDWGSDLGDD SGNAINGIKT RTNNSIASSH ILALNYDHWH YSVVARYWHD GGQWNDDAEL NFGNGNFNVR
0281 STGWGGYLVV GYNF
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 caatgatttt tataataggc tcctctgtat
-070 acgaaatatt tagaaacgca atttgcgcct ttttcactcc cgcaagggat tttcaaacag tggcatacat
0001 atgaaaaaaa cattactggc agccggtgcg gtactggcgc tctcttcgtc ttttactgtc aacgcagctg
0071 aaaacgacaa accgcagtat ctttccgact ggtggcacca gagcgttaac gttgtcggaa gctatcacac
0141 ccgtttcgga ccgcagatcc gcaacgatac ctaccttgag tacgaagcat tcgctaaaaa agactggttc
0211 gacttctatg gttatgcgga tgcgccggta ttcttcggcg gtaactccga tgctaaaggt atctggaacc
0281 acggttctcc gctgtttatg gaaatcgaac cacgtttctc catcgacaag ctgaccaata ctgaccttag
0351 cttcggtccg ttcaaagagt ggtacttcgc gaacaactac atttacgaca tgggtcgtaa taaagatggt
0421 cgccagagca cctggtacat gggtctgggt accgatatcg acactggcct gccgatgagc ctgtccatga
0491 acgtctatgc gaaataccag tggcagaact atggcgcagc gaacgaaaac gagtgggacg gttaccgttt
0561 caaaattaaa tactttgtgc cgattaccga tctgtggggc ggtcagctga gctacatcgg cttcaccaac
0631 ttcgactggg gttccgattt aggggatgac agcggtaacg caatcaacgg tattaagacc cgtactaata
0701 actctatcgc ttccagccat attctggctc tgaactacga tcactggcac tactctgtcg tagctcgtta
0771 ctggcacgac ggtggtcagt ggaacgacga tgcagaactg aacttcggca acggcaactt caacgttcgc
0841 tctaccggct ggggtggtta cctggtagta ggttacaact tctgattatg aaaatgccgg gatttattcc
0911 cggcatttct gattgttaac aacgtgtgct ttgttcatgc cggatgcggc gtaaacgctt tgtccggcca
0981 acaaa
|
