MG1655
W3110
Search for
Japanese | English
Gene Report : basR
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion 4 (LD)  ,  OCR13,15-3 (LD 4E_CRS) (D)  ,  OCR13,15-4 (LD 4E_P/O) (D)  ,  OCR14 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  basR
Related strains
     Strains Search Search strains by gene name:  basR   Search strains by all related name:  basR b4113 ECK4106 f222 JW4074 pmrA

General information  (Go to Linear View:)
 Gene Name basR  
 Alternative name b4113,ECK4106,f222,JW4074,pmrA  
 Location, Length 4,331,305 - 4,331,973 (  -  ) ;   93.35 min ; 669 (bp) ,   222 (aa) Go to Linear View
 Product DNA-binding response regulator in two-component regulatory system with BasS  
 Operon Name basRS  
 Note transcriptional regulatory protein, member of 2-component regulatory system; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_process: GO:0006350 - transcription  
 Function regulator; RNA synthesis, modification, DNA transcription  
 Gene Ontology GO:0000156 ; two-component response regulator activity ( basR )
GO:0000160 ; two-component signal transduction system (phosphorelay) ( basR )
GO:0003677 ; DNA binding ( basR )
GO:0005737 ; cytoplasm ( basR )
GO:0006350 ; transcription ( basR )
GO:0006355 ; regulation of transcription, DNA-dependent ( basR )
GO:0046677 ; response to antibiotic ( basR )
 PID 1790552  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) BASR_ECOLI ( P30843 )
    -  Protein name Transcriptional regulatory protein basR/pmrA.  
    -  Synonyms  
    -  Gene name Name=basR; Synonyms=pmrA; OrderedLocusNames=b4113;  

 Linear View (Whole Mode)
View Location
   4320.0  –  4345.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP basR (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of The Response Regulatory Protein Prra From Mycobacterium Tuberculosis  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Transcriptional regulatory protein basR/pmrA  
         PSI-BLAST Transcriptional regulatory protein srrA (Staphylococcal respiratory response protein A)
    nr     (database updated : 2007.02.20 )
         BLAST DNA-binding response regulator in two-component regulatory system with BasS [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    AMIDATION    SUGAR_TRANSPORT_2     

Other Cross-Reference
    COG COG0745TK 
    EcoCyc basR 

MMBR References
J. Biochem. (Tokyo) 1993;114:350-357
Novel members of the two-component signal transduction genes in Escherichia coli.
Nagasawa, S., K. Ishige, and T. Mizuno.
J Bacteriol. 1993;175:4154-4164
Spontaneous pmrA mutants of Salmonella typhimurium LT2 define a new two-component regulatory system with a possible role in virulence.
Roland, K. L., L. E. Martin, C. R. Esther, and J. K. Spitznagel.

Sequences
Amino acid
FASTA format
0001 MKILIVEDDT LLLQGLILAA QTEGYACDSV TTARMAEQSL EAGHYSLVVL DLGLPDEDGL HFLARIRQKK 
0071 YTLPVLILTA RDTLTDKIAG LDVGADDYLV KPFALEELHA RIRALLRRHN NQGESELIVG NLTLNMGRRQ 
0141 VWMGGEELIL TPKEYALLSR LMLKAGSPVH REILYNDIYN WDNEPSTNTL EVHIHNLRDK VGKARIRTVR 
0211 GFGYMLVANE EN

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             aagacaattt attctccacg ctattgggat 
-070 taactggcgt tgagacgaag tattaccagg ctgcggatga tattctgcaa acttgcagga gagtgagtga 
0001 atgaaaattc tgattgttga agacgatacg ctgttattgc agggactgat tctggcggcg caaaccgaag 
0071 gctacgcgtg cgatagcgtg acaaccgcgc ggatggcgga acaaagcctt gaggcaggtc attacagcct 
0141 ggtggtactg gatttagggt tacccgacga agatggactg cattttctcg cccgtatccg gcagaaaaaa 
0211 tataccctgc cggtactgat cctcaccgct cgcgatacgc tgaccgacaa aatcgccggg ctggatgtcg 
0281 gtgccgacga ctatctggtg aagccttttg cgctggaaga gttacatgcc cgtatccgcg ccctgctacg 
0351 acgccataat aatcagggcg aaagtgagct gattgttggc aatctgacgc tgaacatggg tcgccgtcag 
0421 gtatggatgg gcggtgaaga gttgattctg acgcccaaag aatatgctct gctgtcacgg ttaatgctca 
0491 aagcaggcag tccggtgcat cgggaaattc tctacaacga catctataac tgggacaatg aaccctcgac 
0561 caacaccctg gaagtgcata tccacaatct gcgcgacaaa gtgggcaaag cccgtatccg caccgtgcgc 
0631 ggctttggct atatgctggt cgcgaatgag gaaaactaat tgaatctgat gcattttctg cgccgaccaa 
0701 tatcgctgcg ccaacggctg atattgacca tcggggccat tttgttggtg tttgagctga tcagcgtct