MG1655
W3110
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Gene Report : malZ
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCR39 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  malZ
Related strains
     Strains Search Search strains by gene name:  malZ   Search strains by all related name:  malZ b0403 ECK0397 JW0393

General information  (Go to Linear View:)
 Gene Name malZ  
 Alternative name b0403,ECK0397,JW0393  
 Location, Length 421,742 - 423,556 (  +  ) ;   9.09 min ; 1815 (bp) ,   604 (aa) Go to Linear View
 Product maltodextrin glucosidase  
 Operon Name malZ  
 Note GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0000272 - polysaccharide catabolic process  
 Function enzyme; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0000023 ; maltose metabolic process ( malZ )
GO:0003824 ; catalytic activity ( malZ )
GO:0004558 ; alpha-glucosidase activity ( malZ )
GO:0005737 ; cytoplasm ( malZ )
GO:0005975 ; carbohydrate metabolic process ( malZ )
GO:0008152 ; metabolic process ( malZ )
GO:0016787 ; hydrolase activity ( malZ )
GO:0016798 ; hydrolase activity, acting on glycosyl bonds ( malZ )
GO:0043169 ; cation binding ( malZ )
 PID 345297171  
 EC number
  (KEGG Pathway)
 
3.2.1.20  
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) MALZ_ECOLI ( P21517 )
    -  Protein name Maltodextrin glucosidase  
    -  Synonyms EC 3.2.1.20, Alpha-glucosidase  
    -  Gene name Name=malZ; OrderedLocusNames=b0403;  

 Linear View (Whole Mode)
View Location
   410.0  –  435.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP malZ (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of A Maltogenic Amylase  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Maltodextrin glucosidase  
         PSI-BLAST Maltodextrin glucosidase
    nr     (database updated : 2007.02.20 )
         BLAST maltodextrin glucosidase [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    EcoCyc malZ 

MMBR References
J Bacteriol. 1992;174(5):1709-10.
Alignment of genes from the 9-minute region (araJ to tsx) of the Escherichia coli K-12 linkage map to the physical map.
Lucht JM, Boos W, Bremer E. ( 1537816 )
J Biol Chem. 1996;271:10681-10689
The MalT-dependent and malZ-encoded maltodextrin glucosidase of Escherichia coli can be converted into a dextrinyltransferase by a single mutation.
Peist, R., C. Schneider-Fresenius, and W. Boos.
J Biol Chem. 1991;266:19450-19458
The malZ gene of Escherichia coli, a member of the maltose regulon, encodes a maltodextrin glucosidase.
Tapio, S., F. Yeh, H. Shuman, and W. Boos.

Sequences
Amino acid
FASTA format
0001 MLNAWHLPVP PFVKQSKDQL LITLWLTGED PPQRIMLRTE HDNEEMSVPM HKQRSQPQPG VTAWRAAIDL 
0071 SSGQPRRRYS FKLLWHDRQR WFTPQGFSRM PPARLEQFAV DVPDIGPQWA ADQIFYQIFP DRFARSLPRE 
0141 AEQDHVYYHH AAGQEIILRD WDEPVTAQAG GSTFYGGDLD GISEKLPYLK KLGVTALYLN PVFKAPSVHK 
0211 YDTEDYRHVD PQFGGDGALL RLRHNTQQLG MRLVLDGVFN HSGDSHAWFD RHNRGTGGAC HNPESPWRDW 
0281 YSFSDDGTAL DWLGYASLPK LDYQSESLVN EIYRGEDSIV RHWLKAPWNM DGWRLDVVHM LGEAGGARNN 
0351 MQHVAGITEA AKETQPEAYI VGEHFGDARQ WLQADVEDAA MNYRGFTFPL WGFLANTDIS YDPQQIDAQT 
0421 CMAWMDNYRA GLSHQQQLRM FNQLDSHDTA RFKTLLGRDI ARLPLAVVWL FTWPGVPCIY YGDEVGLDGK 
0491 NDPFCRKPFP WQVEKQDTAL FALYQRMIAL RKKSQALRHG GCQVLYAEDN VVVFVRVLNQ QRVLVAINRG 
0561 EACEVVLPAS PFLNAVQWQC KEGHGQLTDG ILALPAISAT VWMN

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ATCCGCCCCC GTCCTCCTCC CCCAAATATC 
-070 CTTCAGATGA TGAGTGATCC TGCATTAGGC TATGGCAAGG TGATCAGATT TTCATCACAG GGGAATTATG 
0001 atgttaaatg catggcacct gccggtgccc ccatttgtta aacaaagcaa agatcaactg ctcattacac 
0071 tgtggctgac gggcgaagac ccaccgcagc gcattatgct gcgtacagaa cacgataacg aagaaatgtc 
0141 agtaccgatg cataagcagc gcagtcagcc gcagcctggc gtcaccgcat ggcgtgcggc gattgatctc 
0211 tccagcggac aaccccggcg gcgttacagt ttcaaactgc tgtggcacga tcgccagcgt tggtttacac 
0281 cgcagggctt cagccgaatg ccgccggcac gactggagca gtttgccgtc gatgtaccgg atatcggccc 
0351 acaatgggct gcggatcaga ttttttatca gatcttccct gatcgttttg cgcgtagtct tcctcgtgaa 
0421 gctgaacagg atcatgtcta ttaccatcat gcagccggac aagagatcat cttgcgtgac tgggatgaac 
0491 cggtcacggc gcaggcgggc ggatcaacgt tctatggcgg cgatctggac gggataagcg aaaaactgcc 
0561 gtatctgaaa aagcttggcg tgacagcgct gtatctcaat ccggtgttta aagctcccag cgtacataaa 
0631 tacgataccg aggattatcg ccatgtcgat ccgcagtttg gcggtgatgg ggcgttgctg cgtttgcgac 
0701 acaatacgca gcagctggga atgcggctgg tgctggacgg cgtgtttaac cacagtggcg attcccatgc 
0771 ctggtttgac aggcataatc gtggcacggg tggtgcttgt cacaaccccg aatcgccctg gcgcgactgg 
0841 tactcgttta gtgatgatgg cacggcgctc gactggcttg gctatgccag cttgccgaag ctggattatc 
0911 agtcggaaag tctggtgaat gaaatttatc gcggggaaga cagtattgtc cgccactggc tgaaagcgcc 
0981 gtggaatatg gacggctggc ggctggatgt ggtgcatatg ctgggggagg cgggtggggc gcgcaataat 
1051 atgcagcacg ttgccgggat caccgaagcg gcgaaagaaa cccagccgga agcgtatatt gtcggcgaac 
1121 attttggcga tgcacggcaa tggttacagg ccgatgtgga agatgccgcc atgaactatc gtggcttcac 
1191 attcccgttg tggggatttc ttgccaatac cgatatctct tacgatccgc agcaaattga tgcccaaacc 
1261 tgtatggcct ggatggataa ttaccgcgca gggctttctc atcaacaaca attacgtatg tttaatcagc 
1331 tcgacagcca cgatactgcg cgatttaaaa cgctgctcgg tcgggatatt gcgcgcctgc cgctggcggt 
1401 ggtctggctg ttcacctggc ctggtgtacc gtgcatttat tacggtgatg aagtaggact ggatggcaaa 
1471 aacgatccgt tttgccgtaa accgttcccc tggcaggtgg aaaagcagga tacggcgtta ttcgcgctgt 
1541 accagcgaat gattgcgctg cgtaagaaaa gtcaggcgct acgtcatggc ggctgtcagg tgctgtatgc 
1611 ggaagataac gtggtggtat ttgtccgcgt gctgaatcag caacgtgtac tggtggcaat caaccgtggc 
1681 gaggcctgtg aagtggtgct acccgcgtca ccgtttctca atgccgtgca atggcaatgc aaagaagggc 
1751 atgggcaact gactgacggg attctggctt tgcctgccat ttcggctacg gtatggatga actaaCGTTT 
1821 TATAACGCCT TGCGTGACGC CTGCGCCATC ATCCGCGGAT AAAACTGCCA GAAGCGGGTT TCGAGGGCGT 
1891 CATAATGAGC GTCTAAATCG TACCA