MG1655
W3110
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Gene Report : brnQ
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCR39 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  brnQ
Related strains
     Strains Search Search strains by gene name:  brnQ   Search strains by all related name:  brnQ b0401 ECK0395 hrbA JW0391 o439

General information  (Go to Linear View:)
 Gene Name brnQ  
 Alternative name b0401,ECK0395,hrbA,JW0391,o439  
 Location, Length 418,815 - 420,134 (  +  ) ;   9.03 min ; 1320 (bp) ,   439 (aa) Go to Linear View
 Product branched-chain amino acid transport system 2 carrier protein; LIV-II transport system for Ile, Leu, and Val  
 Operon Name brnQ-proY  
 Note branched chain amino acid transport system II carrier protein; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009098 - leucine biosynthetic process; GO_process: GO:0009063 - cellular amino acid catabolic process  
 Function transport; Transport of small molecules: Amino acids, amines  
 Gene Ontology GO:0005886 ; plasma membrane ( brnQ )
GO:0006810 ; transport ( brnQ )
GO:0006865 ; amino acid transport ( brnQ )
GO:0015658 ; branched-chain aliphatic amino acid transmembrane transporter activity ( brnQ )
GO:0015803 ; branched-chain aliphatic amino acid transport ( brnQ )
GO:0016020 ; membrane ( brnQ )
GO:0016021 ; integral to membrane ( brnQ )
 PID 1786601  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) BRNQ_ECOLI ( P37011 ; P77112; P77492 )
    -  Protein name Branched-chain amino acid transport system II carrier protein  
    -  Synonyms LIV- II  
    -  Gene name Name=brnQ; OrderedLocusNames=b0401, z0499, ECs0451;  

 Linear View (Whole Mode)
View Location
   410.0  –  435.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP brnQ (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
        PSI-BLAST  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Branched-chain amino acid transport system II carrier protein (LIV-II)  
         PSI-BLAST Branched-chain amino acid transport system II carrier protein (LIV-II)
    nr     (database updated : 2007.02.20 )
         BLAST Branched-chain amino acid transport system II carrier protein [Escherichia coli CFT073]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    PROKAR_LIPOPROTEIN     

Other Cross-Reference
    COG COG1114E 
    EcoCyc brnQ 

MMBR References
J Bacteriol. 1974;117(2):393-405.
Mutations affecting the different transport systems for isoleucine, leucine, and valine in Escherichia coli K-12.
Guardiola J, De Felice M, Klopotowski T, Iaccarino M. ( 4590465 )
J Bacteriol. 1971;108(3):1034-44.
Escherichia coli K-12 mutants altered in the transport of branched-chain amino acids.
Guardiola J, Iaccarino M. ( 4945181 )

Sequences
Amino acid
FASTA format 
0001 MTHQLRSRDI IALGFMTFAL FVGAGNIIFP PMVGLQAGEH VWTAAFGFLI TAVGLPVLTV VALAKVGGGV 
0071 DSLSTPIGKV AGVLLATVCY LAVGPLFATP RTATVSFEVG IAPLTGDSAL PLFIYSLVYF AIVILVSLYP 
0141 GKLLDTVGNF LAPLKIIALV ILSVAAIVWP AGSISTATEA YQNAAFSNGF VNGYLTMDTL GAMVFGIVIV 
0211 NAARSRGVTE ARLLTRYTVW AGLMAGVGLT LLYLALFRLG SDSASLVDQS ANGAAILHAY VQHTFGGGGS 
0281 FLLAALIFIA CLVTAVGLTC ACAEFFAQYV PLSYRTLVFI LGGFSMVVSN LGLSQLIQIS VPVLTAIYPP 
0351 CIALVVLSFT RSWWHNSSRV IAPPMFISLL FGILDGIKAS AFSDILPSWA QRLPLAEQGL AWLMPTVVMV 
0421 VLAIIWDRAA GRQVTSSAH
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             TATTTCCCGC TAAAATTGTT TAAATATACC 
-070 GCTGTATCAT CCCCAGGGAT TGGCACAAAA ATTTAACGTT ACAACACCAC ATCCACAGGC AGTATGATTT 
0001 atgacccatc aattaagatc gcgcgatatc atcgctctgg gctttatgac atttgcgttg ttcgtcggcg 
0071 caggtaacat tattttccct ccaatggtcg gcttacaggc aggcgaacac gtctggactg cggcattcgg 
0141 cttcctcatt actgccgttg gcctgccggt attaacggta gtggcgctgg caaaagttgg cggcggtgtt 
0211 gacagcctca gcacgccaat cggtaaagtc gctggcgtac tgctggcaac ggtttgttac ctggcggtgg 
0281 ggccgctttt cgctacgccg cgtacagcta ccgtttcctt tgaagtgggg attgcgccgc tgacgggtga 
0351 ttccgcgctg ccgctgttta tctacagcct ggtctatttc gctatcgtta ttctggtttc gctctatccg 
0421 ggcaagctgc tggataccgt gggcaacttc cttgcgccgc tgaaaattat cgcgctggtc atcctgtctg 
0491 ttgccgctat tgtctggccg gcgggttcta tcagcacggc gactgaggct tatcaaaacg ctgcgttttc 
0561 taacggcttc gttaacggct atctgaccat ggatacgctg ggcgcaatgg tgtttggtat cgttattgtt 
0631 aacgcggcgc gttctcgtgg cgttaccgaa gcgcgtctgc tgacccgtta taccgtctgg gctggcctga 
0701 tggcgggtgt tggtctgact ctgctgtacc tggcgctgtt ccgtctgggg tcagacagcg cgtcgctggt 
0771 cgatcagtct gcaaacggcg ctgctattct gcatgcttac gttcagcaca cctttggcgg cggcggtagc 
0841 ttcctgctgg cggcgttaat cttcatcgcc tgcctggtaa cggcagttgg cctgacctgt gcttgtgcag 
0911 aattctttgc ccagtacgta ccgctctctt atcgtacgct ggtgtttatc ctcggcggct tctcgatggt 
0981 ggtttctaac ctcggcttaa gccagctgat ccagatctcc gtaccggtgc tgaccgctat ttatccgccg 
1051 tgtatcgcac tggttgtatt aagttttaca cgctcatggt ggcataattc gtcccgcgtg attgctccgc 
1121 cgatgtttat cagcctgctt tttggtattc tcgacgggat caaagcatct gcattcagcg atatcttacc 
1191 gtcctgggcg cagcgtttac cgctggccga acaaggtctg gcgtggttaa tgccaacagt ggtgatggtg 
1261 gttctggcca ttatctggga tcgcgcggca ggtcgtcagg tgacctccag cgctcactaa ATCACTGAAC 
1331 ATTTGTTTTA ACCACGGGGC TGCGATGCCC CGTGGTTTTT TATTGTGTTG ATGGGTTAGG AATTGATGGA 
1401 AAGTAAGAAC AAGCTAAAGC