|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
J Bacteriol. 1995;177(10):2878-86.
Cloning, characterization, and functional expression of acs, the gene which encodes acetyl coenzyme A synthetase in Escherichia coli.
Kumari S, Tishel R, Eisenbach M, Wolfe AJ.
(
7751300
)
|
|
|
Deletion
|
4
(LD)
,
OCR13
(D)
,
OCR13,15-3 (LD 4E_CRS)
(D)
,
OCR13,15-4 (LD 4E_P/O)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
acs
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
acs
Search strains by all related name:
acs acsA b4069 ECK4062 JW4030 yfaC
|
General information (Go to Linear View: )
|
|
Gene Name
|
acs
|
|
Alternative name
|
acsA,b4069,ECK4062,JW4030,yfaC
|
|
Location, Length
|
4,283,436 - 4,285,394
(
-
)
;
92.32
min
;
1959
(bp) ,
652
(aa)
|
|
Product
|
acetyl-CoA synthetase
|
|
Operon Name
|
acs-yjcH-actP
|
|
Note
|
GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0045733 - acetate catabolic process
|
|
Function
|
enzyme; Fatty acid and phosphatidic acid biosynthesis
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( acs )
GO:0003987
;
acetate-CoA ligase activity ( acs )
GO:0008152
;
metabolic process ( acs )
GO:0016208
;
AMP binding ( acs )
GO:0016874
;
ligase activity ( acs )
|
|
PID
|
1790505
|
EC number
(KEGG Pathway)
|
6.2.1.1
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
ACSA_ECOLI
(
P27550
)
|
|
- Protein name
|
Acetyl-coenzyme A synthetase
|
|
- Synonyms
|
EC 6.2.1.1, Acetate--CoA ligase, Acyl- activating enzyme
|
|
- Gene name
|
Name=acs; OrderedLocusNames=b4069;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
acs
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Acetyl Coa Synthetase, Acetylated On Lys609
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Acetyl-coenzyme A synthetase
|
|
PSI-BLAST
|
Acetyl-coenzyme A synthetase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
acetyl-coenzyme A synthetase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
EF_HAND
AMP_BINDING
|
|
MMBR References
|
J Bacteriol. 1995;177:2878-2886
Cloning, characterization, and functional expression of acs, the gene which encodes acetyl coenzyme A synthetase in Escherichia coli.
Kumari, S., R. Tishel, M. Eisenbach, and A. J. Wolfe.
|
Nucleic Acids Res. 1993;21:5408-5417
Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.
Blattner, F. R., V. D. Burland, G. Plunkett, H. J. Sofia, and D. L. Daniels.
|
| Sequences |
Amino acid
FASTA format
|
0001 MSQIHKHTIP ANIADRCLIN PQQYEAMYQQ SINVPDTFWG EQGKILDWIK PYQKVKNTSF APGNVSIKWY
0071 EDGTLNLAAN CLDRHLQENG DRTAIIWEGD DASQSKHISY KELHRDVCRF ANTLLELGIK KGDVVAIYMP
0141 MVPEAAVAML ACARIGAVHS VIFGGFSPEA VAGRIIDSNS RLVITSDEGV RAGRSIPLKK NVDDALKNPN
0211 VTSVEHVVVL KRTGGKIDWQ EGRDLWWHDL VEQASDQHQA EEMNAEDPLF ILYTSGSTGK PKGVLHTTGG
0281 YLVYAALTFK YVFDYHPGDI YWCTADVGWV TGHSYLLYGP LACGATTLMF EGVPNWPTPA RMAQVVDKHQ
0351 VNILYTAPTA IRALMAEGDK AIEGTDRSSL RILGSVGEPI NPEAWEWYWK KIGNEKCPVV DTWWQTETGG
0421 FMITPLPGAT ELKAGSATRP FFGVQPALVD NEGNPLEGAT EGSLVITDSW PGQARTLFGD HERFEQTYFS
0491 TFKNMYFSGD GARRDEDGYY WITGRVDDVL NVSGHRLGTA EIESALVAHP KIAEAAVVGI PHNIKGQAIY
0561 AYVTLNHGEE PSPELYAEVR NWVRKEIGPL ATPDVLHWTD SLPKTRSGKI MRRILRKIAA GDTSNLGDTS
0631 TLADPGVVEK LLEEKQAIAM PS
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ttgcgtgatc tgtcgcccaa atactaaaca
-070 aaactgccaa tacccctaca tttaacgctt atgccacata ttattaacat cctacaagga gaacaaaagc
0001 atgagccaaa ttcacaaaca caccattcct gccaacatcg cagaccgttg cctgataaac cctcagcagt
0071 acgaggcgat gtatcaacaa tctattaacg tacctgatac cttctggggc gaacagggaa aaattcttga
0141 ctggatcaaa ccttaccaga aggtgaaaaa cacctccttt gcccccggta atgtgtccat taaatggtac
0211 gaggacggca cgctgaatct ggcggcaaac tgccttgacc gccatctgca agaaaacggc gatcgtaccg
0281 ccatcatctg ggaaggcgac gacgccagcc agagcaaaca tatcagctat aaagagctgc accgcgacgt
0351 ctgccgcttc gccaataccc tgctcgagct gggcattaaa aaaggtgatg tggtggcgat ttatatgccg
0421 atggtgccgg aagccgcggt tgcgatgctg gcctgcgccc gcattggcgc ggtgcattcg gtgattttcg
0491 gcggcttctc gccggaagcc gttgccgggc gcattattga ttccaactca cgactggtga tcacttccga
0561 cgaaggtgtg cgtgccgggc gcagtattcc gctgaagaaa aacgttgatg acgcgctgaa aaacccgaac
0631 gtcaccagcg tagagcatgt ggtggtactg aagcgtactg gcgggaaaat tgactggcag gaagggcgcg
0701 acctgtggtg gcacgacctg gttgagcaag cgagcgatca gcaccaggcg gaagagatga acgccgaaga
0771 tccgctgttt attctctaca cctccggttc taccggtaag ccaaaaggtg tgctgcatac taccggcggt
0841 tatctggtgt acgcggcgct gacctttaaa tatgtctttg attatcatcc gggtgatatc tactggtgca
0911 ccgccgatgt gggctgggtg accggacaca gttacttgct gtacggcccg ctggcctgcg gtgcgaccac
0981 gctgatgttt gaaggcgtac ccaactggcc gacgcctgcc cgtatggcgc aggtggtgga caagcatcag
1051 gtcaatattc tctataccgc acccacggcg atccgcgcgc tgatggcgga aggcgataaa gcgatcgaag
1121 gcaccgaccg ttcgtcgctg cgcattctcg gttccgtggg cgagccaatt aacccggaag cgtgggagtg
1191 gtactggaaa aaaatcggca acgagaaatg tccggtggtc gatacctggt ggcagaccga aaccggcggt
1261 ttcatgatca ccccgctgcc tggcgctacc gagctgaaag ccggttcggc aacacgtccg ttcttcggcg
1331 tgcaaccggc gctggtcgat aacgaaggta acccgctgga gggggccacc gaaggtagcc tggtaatcac
1401 cgactcctgg ccgggtcagg cgcgtacgct gtttggcgat cacgaacgtt ttgaacagac ctacttctcc
1471 accttcaaaa atatgtattt cagcggcgac ggcgcgcgtc gcgatgaaga tggctattac tggataaccg
1541 ggcgtgtgga cgacgtgctg aacgtctccg gtcaccgtct ggggacggca gagattgagt cggcgctggt
1611 ggcgcatccg aagattgccg aagccgccgt agtaggtatt ccgcacaata ttaaaggtca ggcgatctac
1681 gcctacgtca cgcttaatca cggggaggaa ccgtcaccag aactgtacgc agaagtccgc aactgggtgc
1751 gtaaagagat tggcccgctg gcgacgccag acgtgctgca ctggaccgac tccctgccta aaacccgctc
1821 cggcaaaatt atgcgccgta ttctgcgcaa aattgcggcg ggcgatacca gcaacctggg cgatacctcg
1891 acgcttgccg atcctggcgt agtcgagaag ctgcttgaag agaagcaggc tatcgcgatg ccatcgtaac
1961 ccacaattgc ccgatgcgag tcggtaacgg tttgtaggcc tgataagacg cgacagcgtc gcatcaggca
2031 ttgattgccg gatgcggcgt aaacgcctt
|
