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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
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Deletion
|
OCR12
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
dgkA
|
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Related strains
|
|
Strains Search
|
Search strains by gene name:
dgkA
Search strains by all related name:
dgkA b4042 ECK4034 JW4002
|
General information (Go to Linear View: )
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Gene Name
|
dgkA
|
|
Alternative name
|
b4042,ECK4034,JW4002
|
|
Location, Length
|
4,254,660 - 4,255,028
(
+
)
;
91.70
min
;
369
(bp) ,
122
(aa)
|
|
Product
|
diacylglycerol kinase
|
|
Operon Name
|
dgkA
|
|
Note
|
GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0008654 - phospholipid biosynthetic process
|
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Function
|
enzyme; Fatty acid and phosphatidic acid biosynthesis
|
|
Gene Ontology
|
GO:0004143
;
diacylglycerol kinase activity ( dgkA )
GO:0005886
;
plasma membrane ( dgkA )
GO:0008654
;
phospholipid biosynthetic process ( dgkA )
GO:0016020
;
membrane ( dgkA )
GO:0016021
;
integral to membrane ( dgkA )
GO:0016301
;
kinase activity ( dgkA )
GO:0016740
;
transferase activity ( dgkA )
|
|
PID
|
1790475
|
EC number
(KEGG Pathway)
|
2.7.1.107
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
dgkA
(
EG10224
)
|
|
Number of removed
|
1 aa cleaved
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
KDGL_ECOLI
(
P00556
)
|
|
- Protein name
|
Diacylglycerol kinase
|
|
- Synonyms
|
EC 2.7.1.107, DAGK, Diglyceride kinase, DGK
|
|
- Gene name
|
OrderedLocusNames=b4042, c5013, z5641, ECs5025, SF4163, S3568;
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MMBR References
|
J Biol Chem. 1983;258:10856-10861
The DNA sequences encoding plsB and dgk loci of Escherichia coli.
Lightner, V. A., R. M. Bell, and P. Modrich.
|
J Biol Chem. 1980;255:9413-9420
Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyltransferase.
Lightner, V. A., T. J. Larsen, P. Tailleur, G. D. Kantor, C. R. H. Raetz, R. M. Bell, and P. Modrich.
|
| Sequences |
Amino acid
FASTA format
|
0001 MANNTTGFTR IIKAAGYSWK GLRAAWINEA AFRQEGVAVL LAVVIACWLD VDAITRVLLI SSVMLVMIVE
0071 ILNSAIEAVV DRIGSEYHEL SGRAKDMGSA AVLIAIIVAV ITWCILLWSH FG
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GTGGTATCCG CTCATGTTTC GCGCGGCGCT
-070 ACGCAAACCC GAATCATCGG ATTTAACGGT ACACTGATAT TGACGCTCAT AATGTAAAAA GGTTCTTTCA
0001 atggccaata ataccactgg attcacccga attatcaaag ctgctggcta ttcctggaaa ggtttacgcg
0071 ctgcatggat caacgaagcg gcattccgtc aggaaggcgt agcggtattg ttggcggtgg tcatcgcctg
0141 ctggctggat gtggacgcga ttacccgcgt gctgcttatc agctccgtga tgctggtgat gattgtggaa
0211 atcctcaata gcgccatcga agcagtggtt gaccgaattg gctctgaata ccatgagctt tccggacgcg
0281 caaaagatat gggatccgct gcggtgctga ttgccattat cgtcgccgtg attacctggt gcattctgtt
0351 atggtcgcat tttggataaC CCTTCCAGAA TTCGATAAAT CTCTGGTTTA TTGTGCAGTT TATGGTTCCA
0421 AAATCGCCTT TTGCTGTATA TACTCACAGC ATAACTGTAT ATACACCCA
|
