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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCR12
(D)
,
DE(xylE-malB)262
,
OCR12-9
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
malF
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Related strains
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Strains Search
|
Search strains by gene name:
malF
Search strains by all related name:
malF b4033 ECK4025 JW3993 malJ
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General information (Go to Linear View: )
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Gene Name
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malF
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Alternative name
|
b4033,ECK4025,JW3993,malJ
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Location, Length
|
4,241,554 - 4,243,098
(
-
)
;
91.42
min
;
1545
(bp) ,
514
(aa)
|
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Product
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maltose transporter subunit
|
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Operon Name
|
malEFG
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Note
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part of maltose permease, periplasmic; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0016052 - carbohydrate catabolic process
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Function
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transport; Transport of small molecules: Carbohydrates, organic acids, alcohols
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Gene Ontology
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GO:0005215
;
transporter activity ( malF )
GO:0005351
;
sugar:hydrogen ion symporter activity ( malF )
GO:0005886
;
plasma membrane ( malF )
GO:0006810
;
transport ( malF )
GO:0008643
;
carbohydrate transport ( malF )
GO:0016020
;
membrane ( malF )
GO:0016021
;
integral to membrane ( malF )
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PID
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1790465
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
MALF_ECOLI
(
P02916
)
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- Protein name
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Maltose transport system permease protein malF.
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- Synonyms
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- Gene name
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Name=malF; OrderedLocusNames=b4033;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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malF
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Maltose transport system permease protein malF
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PSI-BLAST
|
Maltose transport system permease protein malF
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nr
(database updated :
2007.02.20
)
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BLAST
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maltose transporter subunit [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
PROKAR_LIPOPROTEIN
BPD_TRANSP_INN_MEMBR
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MMBR References
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J Bacteriol. 1996;178:2255-2262
Characterization of transmembrane domains 6, 7, and 8 of MalF by mutational analysis.
Ehrle, R., C. Pick, R. Ulrich, E. Hofmann, and M. Ehrmann.
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J Biol Chem. 1984;259:10896-10903
The nucleotide sequence of the gene for malF protein, an inner membrane component of the maltose transport system of Escherichia coli. Repeated DNA sequences are found in the malE-malF intercistronic region.
Froschauer, S., and J. R. Beckwith.
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J Biol Chem. 1991;266:20870-20876
Membrane insertion of the Escherichia coli MalF protein in cells with impaired secretion machinery.
McGovern, K., and J. Beckwith.
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J Bacteriol. 1978;133(3):1358-67.
Permease-specific mutations in Salmonella typhimurium and Escherichia coli that release the glycerol, maltose, melibiose, and lactose transport systems from regulation by the phosphoenolpyruvate:sugar phosphotransferase system.
Saier MH Jr, Straud H, Massman LS, Judice JJ, Newman MJ, Feucht BU.
(
346569
)
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| Sequences |
Amino acid
FASTA format
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0001 MDVIKKKHWW QSDALKWSVL GLLGLLVGYL VVLMYAQGEY LFAITTLILS SAGLYIFANR KAYAWRYVYP
0071 GMAGMGLFVL FPLVCTIAIA FTNYSSTNQL TFERAQEVLL DRSWQAGKTY NFGLYPAGDE WQLALSDGET
0141 GKNYLSDAFK FGGEQKLQLK ETTAQPEGER ANLRVITQNR QALSDITAIL PDGNKVMMSS LRQFSGTQPL
0211 YTLDGDGTLT NNQSGVKYRP NNQIGFYQSI TADGNWGDEK LSPGYTVTTG WKNFTRVFTD EGIQKPFLAI
0281 FVWTVVFSLI TVFLTVAVGM VLACLVQWEA LRGKAVYRVL LILPYAVPSF ISILIFKGLF NQSFGEINMM
0351 LSALFGVKPA WFSDPTTART MLIIVNTWLG YPYMMILCMG LLKAIPDDLY EASAMDGAGP FQNFFKITLP
0421 LLIKPLTPLM IASFAFNFNN FVLIQLLTNG GPDRLGTTTP AGYTDLLVNY TYRIAFEGGG GQDFGLAAAI
0491 ATLIFLLVGA LAIVNLKATR MKFD
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 aacgtatgta ggcctgataa gacgcgtcag
-070 cgtcgcatca ggcagttgtt gtcggataag gcgtgaaagc cttatccgtc ctggaatgag gaagaacccc
0001 atggatgtca ttaaaaagaa acattggtgg caaagcgacg cgctgaaatg gtcagtgcta ggtctgctcg
0071 gcctgctggt gggttacctt gttgttttaa tgtacgcaca aggggaatac ctgttcgcca ttaccacgct
0141 gatattgagt tcagcggggc tgtatatttt cgccaatcgt aaagcctacg cctggcgcta tgtttacccg
0211 ggaatggctg gaatgggatt attcgtcctc ttccctctgg tctgcaccat cgccattgcc ttcaccaact
0281 acagcagcac taaccagctg acttttgaac gtgcgcagga agtgttgtta gatcgctcct ggcaagcagg
0351 caaaacctat aactttggtc tttacccggc gggcgatgag tggcaactgg cgctcagcga cggcgaaacc
0421 ggcaaaaatt acctctccga cgcttttaaa tttggcggcg agcaaaaact gcaactgaaa gaaacgaccg
0491 cccagcccga aggcgaacgc gcgaatctgc gcgtgattac ccagaatcgt caggcgctga gtgacattac
0561 cgccattctg ccggatggca acaaagtgat gatgagctcc ctgcgccagt tttctggcac gcagccgctc
0631 tacacactcg acggtgacgg cacgttgacg aataatcaga gcggcgtgaa atatcgtccg aataaccaaa
0701 ttggctttta ccagtccatt accgccgacg gcaactgggg tgatgaaaag ctaagccccg gttacaccgt
0771 gaccaccggc tggaaaaact ttacccgcgt ctttaccgac gaaggcattc agaaaccgtt cctcgccatt
0841 ttcgtctgga ccgtggtgtt ctcgctgatc actgtctttt taacggtggc ggtcggcatg gttctggcgt
0911 gtctggtgca gtgggaagcg ttgcgcggca aagcggtcta tcgcgtcctg ctgattctgc cctacgcggt
0981 gccatcgttc atttcaatct tgattttcaa agggttgttt aaccagagct tcggtgaaat caacatgatg
1051 ttgagcgcgc tgtttggcgt gaagcccgcc tggttcagcg atccgaccac cgcccgcacg atgctaatta
1121 tcgtcaatac ctggctgggt tatccgtaca tgatgatcct ctgcatgggc ttgctgaaag cgattccgga
1191 cgatttgtat gaagcctcag caatggatgg cgcaggtccg ttccagaact tctttaagat tacgctgccg
1261 ctgctgatta aaccgctgac gccgctgatg atcgccagct tcgcctttaa ctttaacaac ttcgtgctga
1331 ttcaactgtt aaccaacggc ggcccggatc gtcttggcac gaccacgcca gccggttata ccgacctgct
1401 tgttaactac acctaccgca tcgcttttga aggcggcggg ggtcaggact tcggtctggc ggcagcaatt
1471 gccacgctga tcttcctgct ggtgggtgcg ctggcgatag tgaacctgaa agccacgcga atgaagtttg
1541 attaagggag ataacaaaaa tggcaatggt ccaaccgaaa tcgcaaaaag ctcgtttatt tattactcac
1611 ctgctactgc tactttttat cgcagcgatt atgtt
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