|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
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|
References (PMID)
|
J Bacteriol. 1988;170(1):386-92.
Glyoxylate bypass operon of Escherichia coli: cloning and determination of the functional map.
Chung T, Klumpp DJ, LaPorte DC.
(
2826399
)
|
|
|
Deletion
|
OCR11
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
aceB
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
aceB
Search strains by all related name:
aceB b4014 ECK4006 JW3974 mas
|
General information (Go to Linear View: )
|
|
Gene Name
|
aceB
|
|
Alternative name
|
b4014,ECK4006,JW3974,mas
|
|
Location, Length
|
4,213,501 - 4,215,102
(
+
)
;
90.81
min
;
1602
(bp) ,
533
(aa)
|
|
Product
|
malate synthase A
|
|
Operon Name
|
aceBAK
|
|
Note
|
GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006097 - glyoxylate cycle
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Function
|
enzyme; Central intermediary metabolism: Glyoxylate bypass
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( aceB )
GO:0004474
;
malate synthase activity ( aceB )
GO:0005515
;
protein binding ( aceB )
GO:0005737
;
cytoplasm ( aceB )
GO:0006097
;
glyoxylate cycle ( aceB )
GO:0006099
;
tricarboxylic acid cycle ( aceB )
GO:0016740
;
transferase activity ( aceB )
|
|
PID
|
1790444
|
EC number
(KEGG Pathway)
|
2.3.3.9
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
MASY_ECOLI
(
P08997
)
|
|
- Protein name
|
Malate synthase A
|
|
- Synonyms
|
EC 2.3.3.9, MSA
|
|
- Gene name
|
Name=aceB; Synonyms=mas; OrderedLocusNames=b4014;
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Homology Analysis
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|
BLAST
|
|
Bacteria
|
|
GTOP
|
aceB
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Mycobacterium Tuberculosis Malate Synthase In Complex With Magnesium, Malate, And Coenzyme A
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Malate synthase A
|
|
PSI-BLAST
|
Malate synthase, glyoxysomal
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
malate synthase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
MALATE_SYNTHASE
|
|
MMBR References
|
J Bacteriol. 1982;149(1):173-80.
Genetic regulation of the glyoxylate shunt in Escherichia coli K-12.
Maloy SR, Nunn WD.
(
7033207
)
|
J Bacteriol. 1991;173(17):5396-402.
Buoyant density studies of several mecillinam-resistant and division mutants of Escherichia coli.
Bylund JE, Haines MA, Walsh K, Bouloc P, D'Ari R, Higgins ML.
(
1885519
)
|
Nucleic Acids Res. 1988;16(19):9342
Nucleotide sequence of the aceB gene encoding malate synthase A in Escherichia coli.
Byrne C, Stokes HW, Ward KA.
(
3050899
)
|
EMBO J. 1991;10:675-679
Regulation of the acetate operon in Escherichia coli: purification and functional characterization of the IclR repressor.
Cortay, J. C., D. Negre, A. Galinier, B. Duclos, G. Perriere, and A. J. Cozzone.
|
Biochimie. 1989;71(9-10):1043-9.
Utilization of acetate in Escherichia coli: structural organization and differential expression of the ace operon.
Cortay JC, Bleicher F, Duclos B, Cenatiempo Y, Gautier C, Prato JL, Cozzone AJ.
(
2512996
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MTEQATTTDE LAFTRPYGEQ EKQILTAEAV EFLTELVTHF TPQRNKLLAA RIQQQQDIDN GTLPDFISET
0071 ASIRDADWKI RGIPADLEDR RVEITGPVER KMVINALNAN VKVFMADFED SLAPDWNKVI DGQINLRDAV
0141 NGTISYTNEA GKIYQLKPNP AVLICRVRGL HLPEKHVTWR GEAIPGSLFD FALYFFHNYQ ALLAKGSGPY
0211 FYLPKTQSWQ EAAWWSEVFS YAEDRFNLPR GTIKATLLIE TLPAVFQMDE ILHALRDHIV GLNCGRWDYI
0281 FSYIKTLKNY PDRVLPDRQA VTMDKPFLNA YSRLLIKTCH KRGAFAMGGM AAFIPSKDEE HNNQVLNKVK
0351 ADKSLEANNG HDGTWIAHPG LADTAMAVFN DILGSRKNQL EVMREQDAPI TADQLLAPCD GERTEEGMRA
0421 NIRVAVQYIE AWISGNGCVP IYGLMEDAAT AEISRTSIWQ WIHHQKTLSN GKPVTKALFR QMLGEEMKVI
0491 ASELGEERFS QGRFDDAARL MEQITTSDEL IDFLTLPGYR LLA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CATTTTAAAT GAGTAGTCTT AGTTGTGCTG
-070 AACGAAAAGA GCACAACGAT CCTTCGTTCA CAGTGGGGAA GTTTTCGGAT CCATGACGAG GAGCTGCACG
0001 atgactgaac aggcaacaac aaccgatgaa ctggctttca caaggccgta tggcgagcag gagaagcaaa
0071 ttcttactgc cgaagcggta gaatttctga ctgagctggt gacgcatttt acgccacaac gcaataaact
0141 tctggcagcg cgcattcagc agcagcaaga tattgataac ggaacgttgc ctgattttat ttcggaaaca
0211 gcttccattc gcgatgctga ttggaaaatt cgcgggattc ctgcggactt agaagaccgc cgcgtagaga
0281 taactggccc ggtagagcgc aagatggtga tcaacgcgct caacgccaat gtgaaagtct ttatggccga
0351 tttcgaagat tcactggcac cagactggaa caaagtgatc gacgggcaaa ttaacctgcg tgatgcggtt
0421 aacggcacca tcagttacac caatgaagca ggcaaaattt accagctcaa gcccaatcca gcggttttga
0491 tttgtcgggt acgcggtctg cacttgccgg aaaaacatgt cacctggcgt ggtgaggcaa tccccggcag
0561 cctgtttgat tttgcgctct atttcttcca caactatcag gcactgttgg caaagggcag tggtccctat
0631 ttctatctgc cgaaaaccca gtcctggcag gaagcggcct ggtggagcga agtcttcagc tatgcagaag
0701 atcgctttaa tctgccgcgc ggcaccatca aggcgacgtt gctgattgaa acgctgcccg ccgtgttcca
0771 gatggatgaa atccttcacg cgctgcgtga ccatattgtt ggtctgaact gcggtcgttg ggattacatc
0841 ttcagctata tcaaaacgtt gaaaaactat cccgatcgcg tcctgccaga cagacaggca gtgacgatgg
0911 ataaaccatt cctgaatgct tactcacgcc tgttgattaa aacctgccat aaacgcggtg cttttgcgat
0981 gggcggcatg gcggcgttta ttccgagcaa agatgaagag cacaataacc aggtgctcaa caaagtaaaa
1051 gcggataaat cgctggaagc caataacggt cacgatggca catggatcgc tcacccaggc cttgcggaca
1121 cggcaatggc ggtattcaac gacattctcg gctcccgtaa aaatcagctt gaagtgatgc gcgaacaaga
1191 cgcgccgatt actgccgatc agctgctggc accttgtgat ggtgaacgca ccgaagaagg tatgcgcgcc
1261 aacattcgcg tggctgtgca gtacatcgaa gcgtggatct ctggcaacgg ctgtgtgccg atttatggcc
1331 tgatggaaga tgcggcgacg gctgaaattt cccgtacctc gatctggcag tggatccatc atcaaaaaac
1401 gttgagcaat ggcaaaccgg tgaccaaagc cttgttccgc cagatgctgg gcgaagagat gaaagtcatt
1471 gccagcgaac tgggcgaaga acgtttctcc caggggcgtt ttgacgatgc cgcacgcttg atggaacaga
1541 tcaccacttc cgatgagtta attgatttcc tgaccctgcc aggctaccgc ctgttagcgt aaACCACCAC
1611 ATAACTATGG AGCATCTGCA CATGAAAACC CGTACACAAC AAATTGAAGA ATTACAGAAA GAGTGGACTC
1681 AACCGCGTTG GGAAGGCATT AC
|
