MG1655
W3110
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Gene Report : rplL
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCR10,11-11 (AK1-16 / BK2-16) (D)  ,  OCR10,11-16 (BK5-16 / AK7-16) (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  rplL
Related strains
     Strains Search Search strains by gene name:  rplL   Search strains by all related name:  rplL b3986 ECK3977 JW3949

General information  (Go to Linear View:)
 Gene Name rplL  
 Alternative name b3986,ECK3977,JW3949  
 Location, Length 4,178,583 - 4,178,948 (  +  ) ;   90.06 min ; 366 (bp) ,   121 (aa) Go to Linear View
 Product 50S ribosomal subunit protein L7/L12  
 Operon Name rplKAJL-rpoBC  
 Note GO_component: GO:0005737 - cytoplasm; GO_function: GO:0003735 - structural constituent of ribosome; GO_process: GO:0006412 - translation  
 Function structural component; Ribosomal proteins - synthesis, modification  
 Gene Ontology GO:0003735 ; structural constituent of ribosome ( rplL )
GO:0005515 ; protein binding ( rplL )
GO:0005622 ; intracellular ( rplL )
GO:0005840 ; ribosome ( rplL )
GO:0006412 ; translation ( rplL )
GO:0030529 ; ribonucleoprotein complex ( rplL )
 PID 1790418  
 EC number
  (KEGG Pathway)
 
 
Verified Protein Starts (data compiled from literature and appropriate citations are available from EcoGene)
     EcoGene rplL ( EG10873 )  
    Number of removed 1 aa cleaved  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) RL7_ECOLI ( P02392 )
    -  Protein name 50S ribosomal protein L7/L12  
    -  Synonyms L8  
    -  Gene name OrderedLocusNames=b3986, c4943, z5559, ECs4909, SF4059, S3676;  

 Linear View (Whole Mode)
View Location
   4170.0  –  4195.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP rplL (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Nmr Structure Of L7 Dimer From E.Coli  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST 50S ribosomal protein L7/L12  
         PSI-BLAST 50S ribosomal protein L7/L12
    nr     (database updated : 2007.02.20 )
         BLAST 50S ribosomal subunit protein L7/L12 [Shigella sonnei Ss046]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE CK2_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    COG COG0222J 
    EcoCyc rplL 

MMBR References
J Mol Biol. 1987;194(4):609-20.
Transcription products from the rplKAJL-rpoBC gene cluster.
Downing WL, Dennis PP. ( 2443706 )
Proc Natl Acad Sci U S A. 1980;77:2124-2128
Bacteriophage vehicle for the direct cloning of Escherichia coli promoter DNA sequences: feedback regulation of the rplJL-rpoBC operon.
Holowachuk, E. W., J. D. Friesen, and N. Fiil.
J Bacteriol. 1982;152(3):1022-32.
Insertions of transposon Tn5 into ribosomal protein PNA polymerase operons.
Hui I, Maltman K, Little R, Hastrup S, Johnsen M, Fiil N, Dennis P. ( 6292159 )
Proc Natl Acad Sci U S A. 1980;77:3331-3335
Attenuation and processing of RNA from the rplJL-rpoBC transcription unit of Escherichia coli.
Barry, G., C. Squires, and C. L. Squires.
Proc Natl Acad Sci U S A. 1979;76:4922-4926
Control features within the rplJL-rpoBC transcription unit of Escherichia coli.
Barry, G., C. L. Squires, and C. Squires.
J Bacteriol. 1979;140(2):479-89.
Lambda transducing bacteriophage carrying deletions of the argCBH-rpoBC region of the Escherichia coli chromosome.
Linn T, Goman M, Scaife J. ( 159290 )
J Bacteriol. 1981;147(1):25-35.
Transcriptional and post-transcriptional control of ribosomal protein and ribonucleic acid polymerase genes.
Little R, Fiil NP, Dennis PP. ( 7016843 )
Mol Gen Genet. 1981;184(3):548-50.
Internal promoters of the rpoBC operon of Escherichia coli.
Ma JC, Newman AJ, Hayward RS. ( 6278264 )
Mol Gen Genet. 1980;177(3):527-33.
Cloning of DNA of the rpoBC operon from the chromosome of Escherichia coli K12.
Newman A, Hayward RS. ( 6246404 )
J Bacteriol. 1984;158(1):279-85.
Relative activities of the transcriptional regulatory sites in the rplKAJLrpoBC gene cluster of Escherichia coli.
Ralling G, Linn T. ( 6325390 )
J Mol Biol. 1991;218(1):23-31.
In vivo analysis of overlapping transcription units in the rplKAJLrpoBC ribosomal protein-RNA polymerase gene cluster of Escherichia coli.
Steward KL, Linn T. ( 1825852 )
Mol Gen Genet. 1981;183(2):277-82.
In vivo synthesis of a polycistronic messenger RNA for the ribosomal proteins L11, L1, L10 and L7/12 in Escherichia coli.
Bruckner R, Matzura H. ( 7035827 )
J Bacteriol. 1980;144(3):904-16.
Characterization of promoter-cloning plasmids: analysis of operon structure in the rif region of Escherichia coli and isolation of an enhanced internal promoter mutant.
An G, Friesen JD. ( 7002914 )

Sequences
Amino acid
FASTA format
0001 MSITKDQIIE AVAAMSVMDV VELISAMEEK FGVSAAAAVA VAAGPVEAAE EKTEFDVILK AAGANKVAVI 
0071 KAVRGATGLG LKEAKDLVES APAALKEGVS KDDAEALKKA LEEAGAEVEV K

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             GGCTGCTGTA CGCGATGCGA AAGAAGCTGC 
-070 TTAATCGCAG TTATCTTTTT AACGCATTCG CTTACGTATA AACTTATTCT GATATTCAGG AACAATTTAA 
0001 atgtctatca ctaaagatca aatcattgaa gcagttgcag ctatgtctgt aatggacgtt gtagaactga 
0071 tctctgcaat ggaagaaaaa ttcggtgttt ccgctgctgc tgctgtagct gtagctgctg gcccggttga 
0141 agctgctgaa gaaaaaactg aattcgacgt aattctgaaa gctgctggcg ctaacaaagt tgctgttatc 
0211 aaagcagtac gtggcgcaac tggcctgggt ctgaaagaag ctaaagacct ggtagaatct gcaccggctg 
0281 ctctgaaaga aggcgtgagc aaagacgacg cagaagcact gaaaaaagct ctggaagaag ctggcgctga 
0351 agttgaagtt aaataaGCCA ACCCTTCCGG TTGCAGCCTG AGAAATCAGG CTGATGGCTG GTGACTTTTT 
0421 AGTCACCAGC CTTTTTGCGC TGTAAGGCGC CAGTAGCGTT TCACAC