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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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|
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Deletion
|
OCR09
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
katG
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Related strains
|
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Strains Search
|
Search strains by gene name:
katG
Search strains by all related name:
katG b3942 ECK3934 JW3914 o726
|
General information (Go to Linear View: )
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Gene Name
|
katG
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|
Alternative name
|
b3942,ECK3934,JW3914,o726
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|
Location, Length
|
4,131,858 - 4,134,038
(
+
)
;
89.05
min
;
2181
(bp) ,
726
(aa)
|
|
Product
|
catalase-peroxidase HPI, heme b-containing
|
|
Operon Name
|
katG
|
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Note
|
catalase; hydroperoxidase HPI(I); GO_process: GO:0006805 - xenobiotic metabolic process
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Function
|
enzyme; Detoxification
|
|
Gene Ontology
|
GO:0004096
;
catalase activity ( katG )
GO:0004601
;
peroxidase activity ( katG )
GO:0005506
;
iron ion binding ( katG )
GO:0006118
;
electron transport ( katG )
GO:0006979
;
response to oxidative stress ( katG )
GO:0016491
;
oxidoreductase activity ( katG )
GO:0020037
;
heme binding ( katG )
GO:0042744
;
hydrogen peroxide catabolic process ( katG )
GO:0046872
;
metal ion binding ( katG )
|
|
PID
|
1790378
|
EC number
(KEGG Pathway)
|
1.11.1.6
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
CATA_ECOLI
(
P13029
)
|
|
- Protein name
|
Peroxidase/catalase HPI
|
|
- Synonyms
|
EC 1.11.1.6, Catalase-peroxidase, Hydroperoxidase I
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- Gene name
|
Name=katG; OrderedLocusNames=b3942;
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Homology Analysis
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BLAST
|
|
Bacteria
|
|
GTOP
|
katG
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
Chain A, Crystal Structure Of D141e Mutant Of Bpkatg
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Peroxidase/catalase HPI
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PSI-BLAST
|
Peroxidase/catalase HPI
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
catalase/hydroperoxidase HPI(I) [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
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|
Pfam
|
|
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PROSITE
|
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PROSITE
|
ASN_GLYCOSYLATION
GLYCOSAMINOGLYCAN
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
ATP_GTP_A
PEROXIDASE_1
PEROXIDASE_2
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MMBR References
|
J Bacteriol. 1985;162(2):661-7.
Genetic mapping of katG, a locus that affects synthesis of the bifunctional catalase-peroxidase hydroperoxidase I in Escherichia coli.
Loewen PC, Triggs BL, George CS, Hrabarchuk BE.
(
3886630
)
|
J Bacteriol. 1994;176:2300-2307
Induction of Escherichia coli hydroperoxidase I by acetate and other weak acids.
Mukhopadhyay, B., and H. E. Schellhorn.
|
FEMS Microbiol Lett. 1995;131(2):113-9.
Regulation of hydroperoxidase (catalase) expression in Escherichia coli.
Schellhorn HE.
(
7557318
)
|
J Bacteriol. 1988;170(9):4415-9.
Nucleotide sequence of katG, encoding catalase HPI of Escherichia coli.
Triggs-Raine BL, Doble BW, Mulvey MR, Sorby PA, Loewen PC.
(
3045098
)
|
Gene. 1987;52(2-3):121-8.
Physical characterization of katG, encoding catalase HPI of Escherichia coli.
Triggs-Raine BL, Loewen PC.
(
3038676
)
|
J Bacteriol. 1997;179:4158-4163
RpoS- and OxyR-independent induction of HPI catalase at stationary phase in Escherichia coli and identification of rpoS mutations in common laboratory strains.
Visick, J., and S. Clarke.
|
| Sequences |
Amino acid
FASTA format
|
0001 MSTSDDIHNT TATGKCPFHQ GGHDQSAGAG TTTRDWWPNQ LRVDLLNQHS NRSNPLGEDF DYRKEFSKLD
0071 YYGLKKDLKA LLTESQPWWP ADWGSYAGLF IRMAWHGAGT YRSIDGRGGA GRGQQRFAPL NSWPDNVSLD
0141 KARRLLWPIK QKYGQKISWA DLFILAGNVA LENSGFRTFG FGAGREDVWE PDLDVNWGDE KAWLTHRHPE
0211 ALAKAPLGAT EMGLIYVNPE GPDHSGEPLS AAAAIRATFG NMGMNDEETV ALIAGGHTLG KTHGAGPTSN
0281 VGPDPEAAPI EEQGLGWAST YGSGVGADAI TSGLEVVWTQ TPTQWSNYFF ENLFKYEWVQ TRSPAGAIQF
0351 EAVDAPEIIP DPFDPSKKRK PTMLVTDLTL RFDPEFEKIS RRFLNDPQAF NEAFARAWFK LTHRDMGPKS
0421 RYIGPEVPKE DLIWQDPLPQ PIYNPTEQDI IDLKFAIADS GLSVSELVSV AWASASTFRG GDKRGGANGA
0491 RLALMPQRDW DVNAAAVRAL PVLEKIQKES GKASLADIIV LAGVVGVEKA ASAAGLSIHV PFAPGRVDAR
0561 QDQTDIEMFE LLEPIADGFR NYRARLDVST TESLLIDKAQ QLTLTAPEMT ALVGGMRVLG ANFDGSKNGV
0631 FTDRVGVLSN DFFVNLLDMR YEWKATDESK ELFEGRDRET GEVKFTASRA DLVFGSNSVL RAVAEVYASS
0701 DAHEKFVKDF VAAWVKVMNL DRFDLL
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TATGTAAGAT CTCAACTATC GCATCCGTGG
-070 ATTAATTCAA TTATAACTTC TCTCTAACGC TGTGTATCGT AACGGTAACA CTGTAGAGGG GAGCACATTG
0001 atgagcacgt cagacgatat ccataacacc acagccactg gcaaatgccc gttccatcag ggcggtcacg
0071 accagagtgc gggggcgggc acaaccactc gcgactggtg gccaaatcaa cttcgtgttg acctgttaaa
0141 ccaacattct aatcgttcta acccactggg tgaggacttt gactaccgca aagaattcag caaattagat
0211 tactacggcc tgaaaaaaga tctgaaagcc ctgttgacag aatctcaacc gtggtggcca gccgactggg
0281 gcagttacgc cggtctgttt attcgtatgg cctggcacgg cgcggggact taccgttcaa tcgatggacg
0351 cggtggcgcg ggtcgtggtc agcaacgttt tgcaccgctg aactcctggc cggataacgt aagcctcgat
0421 aaagcgcgtc gcctgttgtg gccaatcaaa cagaaatatg gtcagaaaat ctcctgggcc gacctgttta
0491 tcctcgcggg taacgtggcg ctagaaaact ccggcttccg taccttcggt tttggtgccg gtcgtgaaga
0561 cgtctgggaa ccggatctgg atgttaactg gggtgatgaa aaagcctggc tgactcaccg tcatccggaa
0631 gcgctggcga aagcaccgct gggtgcaacc gagatgggtc tgatttacgt taacccggaa ggcccggatc
0701 acagcggcga accgctttct gcggcagcag ctatccgcgc gaccttcggc aacatgggca tgaacgacga
0771 agaaaccgtg gcgctgattg cgggtggtca tacgctgggt aaaacccacg gtgccggtcc gacatcaaat
0841 gtaggtcctg atccagaagc tgcaccgatt gaagaacaag gtttaggttg ggcgagcact tacggcagcg
0911 gcgttggcgc agatgccatt acctctggtc tggaagtagt ctggacccag acgccgaccc agtggagcaa
0981 ctatttcttc gagaacctgt tcaagtatga gtgggtacag acccgcagcc cggctggcgc aatccagttc
1051 gaagcggtag acgcaccgga aattatcccg gatccgtttg atccgtcgaa gaaacgtaaa ccgacaatgc
1121 tggtgaccga cctgacgctg cgttttgatc ctgagttcga gaagatctct cgtcgtttcc tcaacgatcc
1191 gcaggcgttc aacgaagcct ttgcccgtgc ctggttcaaa ctgacgcaca gggatatggg gccgaaatct
1261 cgctacatcg ggccggaagt gccgaaagaa gatctgatct ggcaagatcc gctgccgcag ccgatctaca
1331 acccgaccga gcaggacatt atcgatctga aattcgcgat tgcggattct ggtctgtctg ttagtgagct
1401 ggtatcggtg gcctgggcat ctgcttctac cttccgtggt ggcgacaaac gcggtggtgc caacggtgcg
1471 cgtctggcat taatgccgca gcgcgactgg gatgtgaacg ccgcagccgt tcgtgctctg cctgttctgg
1541 agaaaatcca gaaagagtct ggtaaagcct cgctggcgga tatcatagtg ctggctggtg tggttggtgt
1611 tgagaaagcc gcaagcgccg caggtttgag cattcatgta ccgtttgcgc cgggtcgcgt tgatgcgcgt
1681 caggatcaga ctgacattga gatgtttgag ctgctggagc caattgctga cggtttccgt aactatcgcg
1751 ctcgtctgga cgtttccacc accgagtcac tgctgatcga caaagcacag caactgacgc tgaccgcgcc
1821 ggaaatgact gcgctggtgg gcggcatgcg tgtactgggt gccaacttcg atggcagcaa aaacggcgtc
1891 ttcactgacc gcgttggcgt attgagcaat gacttcttcg tgaacttgct ggatatgcgt tacgagtgga
1961 aagcgaccga cgaatcgaaa gagctgttcg aaggccgtga ccgtgaaacc ggcgaagtga aatttacggc
2031 cagccgtgcg gatctggtgt ttggttctaa ctccgtcctg cgtgcggtgg cggaagttta cgccagtagc
2101 gatgcccacg agaagtttgt taaagacttc gtggcggcat gggtgaaagt gatgaacctc gaccgtttcg
2171 acctgctgta aTCTGACCCC GTTCAGCGGC TGCTTGCTGG CAGTCGCTGA ACGTTCTTTA CCAGCGTATA
2241 GTGGGCGAAC GAAAACTACA CACTGGATCT CTCATGTCTG C
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