MG1655
W3110
Search for
Japanese | English
Top Genes Deletions Circular Linear Motif Contigs Reference SequenceCutter Download Strains TEC
Gene Report : fdoG
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Microbiology. 1997;143 (Pt 8):2657-64.
Suppression of Escherichia coli formate hydrogenlyase activity by trimethylamine N-oxide is due to drainage of the inducer formate.
Abaibou H, Giordano G, Mandrand-Berthelot MA. ( 9274019 )
     Deletion OCR07 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fdoG
Related strains
     Strains Search Search strains by gene name:  fdoG   Search strains by all related name:  fdoG b3894 ECK3887 JW3865

General information  (Go to Linear View:)
 Gene Name fdoG  
 Alternative name b3894,ECK3887,JW3865  
 Location, Length 4,080,795 - 4,083,845 (  -  ) ;   87.95 min ; 3051 (bp) ,   1016 (aa) Go to Linear View
 Product formate dehydrogenase-O, large subunit  
 Operon Name fdoGHI-fdhE  
 Note formate dehydrogenase-O, major subunit; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0009061 - anaerobic respiration  
 Function enzyme; Energy metabolism, carbon: Anaerobic respiration  
 Gene Ontology GO:0005488 ; binding ( fdoG )
GO:0005506 ; iron ion binding ( fdoG )
GO:0005515 ; protein binding ( fdoG )
GO:0005737 ; cytoplasm ( fdoG )
GO:0006118 ; electron transport ( fdoG )
GO:0008430 ; selenium binding ( fdoG )
GO:0008863 ; formate dehydrogenase activity ( fdoG )
GO:0016491 ; oxidoreductase activity ( fdoG )
GO:0030151 ; molybdenum ion binding ( fdoG )
GO:0045333 ; cellular respiration ( fdoG )
GO:0046872 ; metal ion binding ( fdoG )
GO:0051536 ; iron-sulfur cluster binding ( fdoG )
GO:0051539 ; 4 iron, 4 sulfur cluster binding ( fdoG )
 PID 3868720  
 EC number
  (KEGG Pathway)   		1.2.1.2  
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) FDOG_ECOLI ( P32176 ; P78131 )
    -  Protein name Formate dehydrogenase-O, major subunit  
    -  Synonyms EC 1.2.1.2, Formate dehydrogenase-O alpha subunit, FDH-Z alpha subunit, Aerobic formate dehydrogenase major subunit  
    -  Gene name Name=fdoG; OrderedLocusNames=b3894;  

 Linear View (Whole Mode)
View Location
   4070.0  –  4095.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fdoG (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Formate Dehydrogenase N From E. Coli  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Formate dehydrogenase-O, major subunit  
         PSI-BLAST Formate dehydrogenase-O, major subunit
    nr     (database updated : 2007.02.20 )
         BLAST formate dehydrogenase-O, large subunit [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    GLYCOSAMINOGLYCAN    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    MOLYBDOPTERIN_PROK_1    MOLYBDOPTERIN_PROK_3     

Other Cross-Reference
    COG COG0243C 
    EcoCyc fdoG 

MMBR References
J Bacteriol. 1995;177:7141-7149
Expression and characterization of the Escherichia coli fdo locus and a possible role for aerobic formate dehydrogenase.
Abaibou, H., J. Pommier, S. Benoit, G. Giordano, and M.-A. Mandrand-Berthelot.
Nucleic Acids Res. 1993;21:3391-3398
Analysis of the Escherichia coli genome. III. DNA sequence of the region from 87.2 to 89.2 minutes.
Plunkett, G., V. D. Burland, D. L. Daniels, and F. R. Blattner.

Sequences
Amino acid
FASTA format 
0001 MQVSRRQFFK ICAGGMAGTT AAALGFAPSV ALAETRQYKL LRTRETRNTC TYCSVGCGLL MYSLGDGAKN 
0071 AKASIFHIEG DPDHPVNRGA LCPKGAGLVD FIHSESRLKF PEYRAPGSDK WQQISWEEAF DRIAKLMKED 
0141 RDANYIAQNA EGVTVNRWLS TGMLCASASS NETGYLTQKF SRALGMLAVD NQARVUHGPT VASLAPTFGR 
0211 GAMTNHWVDI KNANLVVVMG GNAAEAHPVG FRWAMEAKIH NGAKLIVIDP RFTRTAAVAD YYAPIRSGTD 
0281 IAFLSGVLLY LLNNEKFNRE YTEAYTNASL IVREDYGFED GLFTGYDAEK RKYDKSSWTY ELDENGFAKR 
0351 DTTLQHPRCV WNLLKQHVSR YTPDVVENIC GTPKDAFLKV CEYIAETSAH DKTASFLYAL GWTQHSVGAQ 
0421 NIRTMAMIQL LLGNMGMAGG GVNALRGHSN IQGLTDLGLL SQSLPGYMTL PSEKQTDLQT YLTANTPKPL 
0491 LEGQVNYWGN YPKFFVSMMK AFFGDKATAE NSWGFDWLPK WDKGYDVLQY FEMMKEGKVN GYICQGFNPV 
0561 ASFPNKNKVI GCLSKLKFLV TIDPLNTETS NFWQNHGELN EVDSSKIQTE VFRLPSTCFA EENGSIVNSG 
0631 RWLQWHWKGA DAPGIALTDG EILSGIFLRL RKMYAEQGGA NPDQVLNMTW NYAIPHEPSS EEVAMESNGK 
0701 ALADITDPAT GAVIVKKGQQ LSSFAQLRDD GTTSCGCWIF AGSWTPEGNQ MARRDNADPS GLGNTLGWAW 
0771 AWPLNRRILY NRASADPQGN PWDPKRQLLK WDGTKWTGWD IPDYSAAPPG SGVGPFIMQQ EGMGRLFALD 
0841 KMAEGPFPEH YEPFETPLGT NPLHPNVISN PAARIFKDDA EALGKADKFP YVGTTYRLTE HFHYWTKHAL 
0911 LNAILQPEQF VEIGESLANK LGIAQGDTVK VSSNRGYIKA KAVVTKRIRT LKANGKDIDT IGIPIHWGYE 
0981 GVAKKGFIAN TLTPFVGDAN TQTPEFKSFL VNVEKV
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             ctttgcggcc ccttccgcaa agaaaaataa 
-070 ctcccactcc ctgcacacgc agcaagcgaa tgtaaatggg acgtgacaat gtcgaaacaa ggagcaatcc 
0001 atgcaggtca gcagaaggca gttctttaag atctgcgctg gcggtatggc aggcaccacg gcagcggcac 
0071 tgggttttgc acccagcgta gcactcgcgg aaacccggca gtataaactg ctgcgcaccc gcgaaacccg 
0141 taatacctgc acctattgtt ccgtaggctg tgggctgttg atgtacagcc tcggtgacgg agcaaaaaac 
0211 gccaaagcat ctatcttcca tatcgaaggc gatccggatc acccggtcaa ccgcggtgca ctttgtccga 
0281 aaggcgctgg cctggtggat ttcatccact ccgaaagccg tctgaagttt ccggaatacc gtgcgccagg 
0351 ttctgataaa tggcagcaaa tcagttggga agaggcgttt gatcgcatcg ccaaactgat gaaagaagac 
0421 cgcgatgcta actacattgc gcaaaacgcc gaaggcgtga ctgttaaccg ctggctctcc accgggatgc 
0491 tgtgtgcttc cgcgtcgagt aacgaaaccg gctatttaac gcaaaaattc tcccgcgcgc tgggtatgct 
0561 cgcggtcgac aaccaggcgc gtgtctgaca cggaccaacg gtagcaagtc ttgctccaac atttggtcgc 
0631 ggtgcgatga ccaaccactg ggtcgacatc aagaacgcca acctcgtcgt ggtgatgggc ggtaacgccg 
0701 ctgaagctca cccggtcggg ttccgctggg cgatggaagc caaaattcac aacggcgcga agctgattgt 
0771 gatcgatcct cgctttacgc gtacggcggc ggtagctgac tactatgccc ctattcgttc cggtactgac 
0841 attgctttcc tgtcaggcgt attgctgtac ctgctgaaca atgaaaaatt caaccgcgaa tacaccgaag 
0911 cctataccaa cgccagcctg atcgtgcgtg aggattacgg ctttgaagat ggcctgttca ccggctacga 
0981 cgcggaaaaa cgcaagtacg ataaatcctc ctggacttat gaactggacg aaaacggctt cgccaaacgc 
1051 gataccacgc tgcaacatcc gcgctgcgtg tggaacttgc tgaaacagca cgtttcccgc tacacgccag 
1121 atgtggttga aaacatctgt ggtacgccaa aagacgcgtt cctgaaagtc tgcgaataca tcgcagaaac 
1191 cagtgctcac gataaaactg cctcgttcct gtatgccctc ggctggacgc aacactccgt tggtgcgcaa 
1261 aacattcgta cgatggcgat gatccagctg ctgctcggca atatggggat ggcaggcggc ggcgttaacg 
1331 ccctgcgcgg tcactccaat attcaggggc tgacggacct ggggctgctg tcgcagagcc tgccaggtta 
1401 catgacgctg ccaagcgaga agcagaccga tctgcaaacc taccttaccg ccaacacgcc aaaaccgctg 
1471 ctggaaggcc aggtaaacta ctggggcaac tacccgaaat tcttcgtctc tatgatgaag gccttctttg 
1541 gtgataaagc gacggcggaa aatagctggg gctttgactg gttgccgaag tgggataaag gctacgacgt 
1611 cctgcaatac ttcgagatga tgaaagaggg caaggtcaat ggctatatct gccagggctt taaccctgtt 
1681 gcctcattcc cgaacaaaaa caaagtgatc ggttgtctgt cgaaactgaa gttcctcgtc accatcgacc 
1751 cactgaacac tgaaacctct aacttctggc agaaccacgg tgagctgaac gaagttgact cgtcgaagat 
1821 ccagaccgaa gtgttccgtc tgccatcgac ctgcttcgcg gaagagaacg gttctatcgt taactcaggt 
1891 cgctggttac agtggcactg gaaaggtgcg gacgccccgg ggattgcgct gactgacggc gagatcctct 
1961 ccggtatctt cctgcgcttg cgcaagatgt atgccgaaca gggtggcgcg aacccggacc aggtgctgaa 
2031 catgacatgg aactacgcca ttccgcatga gccatcttca gaagaagtgg cgatggagag caacggtaag 
2101 gcgctggccg atattaccga tccggcaacc ggtgcggtta tcgtcaagaa aggccaacaa cttagttcgt 
2171 tcgcccaatt gcgcgatgac ggtacaacct cctgtggctg ctggattttc gccggtagct ggacgccgga 
2241 aggcaaccag atggcacgcc gtgataacgc cgatccgtct ggcctcggta acacgctggg ctgggcatgg 
2311 gcatggccgc ttaaccgccg cattctgtat aaccgcgcct ccgcagatcc gcagggtaac ccgtgggatc 
2381 cgaagcgtca gttgctgaaa tgggacggca ctaagtggac cggctgggat attccggact acagcgcagc 
2451 gcctccgggt agcggcgtcg ggccgtttat catgcagcag gaaggcatgg ggcgtctgtt tgccctcgat 
2521 aagatggcgg aaggtccgtt cccggaacac tacgagccgt ttgaaacgcc gctgggaact aacccgctgc 
2591 atccaaacgt tatctcgaac ccggctgcac gtatctttaa agacgacgcc gaagcattgg gtaaagccga 
2661 taagttcccg tatgtcggaa ccacctatcg tctgaccgag cacttccact actggaccaa acacgcgctg 
2731 ttgaacgcga ttttgcagcc agagcagttt gtggaaatcg gggagtcgct ggcgaataaa cttggcattg 
2801 cccagggcga taccgtgaaa gtctcctcca accgtggcta tatcaaagcc aaagcggtgg tgaccaaacg 
2871 tattcgcacg ctgaaagcga acggcaaaga tatcgatacc atcggtattc cgattcactg gggctatgaa 
2941 ggcgtagcta aaaaaggctt tattgccaat actttaacgc cattcgttgg tgatgcgaac acgcagacgc 
3011 cggagtttaa gtccttcctt gtgaatgtgg aaaaggtgta acggagacga catatggctt atcaatctca 
3081 agatatcatt cgtcgttccg cgactaacgg tctgaccccc gcgcctcagg cgcgggactt ccaggaagaa 
3151 g