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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
J Bacteriol. 1995;177(11):3326-31.
Cloning and characterization of the Escherichia coli hemN gene encoding the oxygen-independent coproporphyrinogen III oxidase.
Troup B, Hungerer C, Jahn D.
(
7768836
)
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Deletion
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OCR06-18 (AK5-15 / BK6-15)
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
hemN
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Related strains
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Strains Search
|
Search strains by gene name:
hemN
Search strains by all related name:
hemN b3867 ECK3860 JW3838 o459 yihJ
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General information (Go to Linear View: )
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Gene Name
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hemN
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Alternative name
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b3867,ECK3860,JW3838,o459,yihJ
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Location, Length
|
4,050,068 - 4,051,441
(
+
)
;
87.29
min
;
1374
(bp) ,
457
(aa)
|
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Product
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coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent
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Operon Name
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hemN
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Note
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O2-independent coproporphyrinogen III oxidase
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Function
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enzyme; Biosynthesis of cofactors, carriers: Heme, porphyrin
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Gene Ontology
|
GO:0003824
;
catalytic activity ( hemN )
GO:0004109
;
coproporphyrinogen oxidase activity ( hemN )
GO:0005506
;
iron ion binding ( hemN )
GO:0005737
;
cytoplasm ( hemN )
GO:0006779
;
porphyrin biosynthetic process ( hemN )
GO:0016491
;
oxidoreductase activity ( hemN )
GO:0046872
;
metal ion binding ( hemN )
GO:0051536
;
iron-sulfur cluster binding ( hemN )
GO:0051539
;
4 iron, 4 sulfur cluster binding ( hemN )
GO:0051989
;
coproporphyrinogen dehydrogenase activity ( hemN )
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PID
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87082341
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EC number
(KEGG Pathway)
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1.3.99.22
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
HEMN_ECOLI
(
P32131
;
P76772
)
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- Protein name
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Oxygen-independent coproporphyrinogen III oxidase
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- Synonyms
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EC 1.-.-.-, Coproporphyrinogenase, Coprogen oxidase
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- Gene name
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Name=hemN; OrderedLocusNames=b3867;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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hemN
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
Chain A, Coproporphyrinogen Iii Oxidase
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Oxygen-independent coproporphyrinogen III oxidase
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PSI-BLAST
|
Oxygen-independent coproporphyrinogen III oxidase
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nr
(database updated :
2007.02.20
)
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BLAST
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O2-independent coproporphyrinogen III oxidase [Shigella sonnei Ss046]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
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| Sequences |
Amino acid
FASTA format
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0001 MSVQQIDWDL ALIQKYNYSG PRYTSYPTAL EFSEDFGEQA FLQAVARYPE RPLSLYVHIP FCHKLCYFCG
0071 CNKIVTRQQH KADQYLDALE QEIVHRAPLF AGRHVSQLHW GGGTPTYLNK AQISRLMKLL RENFQFNADA
0141 EISIEVDPRE IELDVLDHLR AEGFNRLSMG VQDFNKEVQR LVNREQDEEF IFALLNHARE IGFTSTNIDL
0211 IYGLPKQTPE SFAFTLKRVA ELNPDRLSVF NYAHLPTIFA AQRKIKDADL PSPQQKLDIL QETIAFLTQS
0281 GYQFIGMDHF ARPDDELAVA QREGVLHRNF QGYTTQGDTD LLGMGVSAIS MIGDCYAQNQ KELKQYYQQV
0351 DEQGNALWRG IALTRDDCIR RDVIKSLICN FRLDYAPIEK QWDLHFADYF AEDLKLLAPL AKDGLVDVDE
0421 KGIQVTAKGR LLIRNICMCF DTYLRQKARM QQFSRVI
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TGTCGCGGCG ACAAAAGTGG CTGCGCAACC
-070 GGCTGATGAC CCGAAACGGG CATCCGCCGG TACGCCGTAG CCGCCAGAGA CGCCATCGGA AGGAGTGAGC
0001 atgtctgtac agcaaatcga ctgggatctg gccctgatcc agaaatataa ctattccggg ccacgataca
0071 cctcgtaccc gaccgcgctg gagttttcag aagacttcgg cgaacaggcg tttttacaag ccgtggcgcg
0141 ctatcctgag cgtccattat ctctctacgt acatatcccg ttctgccata agctttgtta cttctgcggt
0211 tgcaataaga ttgttactcg ccagcagcac aaggccgatc agtatctgga cgcgctggag caagaaatcg
0281 tccatcgtgc accgctgttc gccgggcgtc acgtcagcca attgcactgg ggcggcggaa cgccgacgta
0351 tctgaataaa gcgcaaatca gccgcctgat gaagctgctg cgcgaaaact tccagttcaa tgccgatgcg
0421 gagatttcga tcgaagtcga tccgcgggaa atcgaactgg atgtactcga tcatttacgc gccgaaggct
0491 ttaatcgcct gagcatgggc gtgcaggact tcaacaaaga agtgcaacgt ctggttaacc gcgagcagga
0561 tgaagagttc atctttgcac tgcttaacca tgcgcgtgag attggtttta cctccaccaa catcgacctg
0631 atttacggcc tgccgaaaca gacgccggag agtttcgcct ttaccctgaa acgtgtggcg gagctgaacc
0701 ccgatcgtct gagtgtcttt aactacgcgc atctgccgac catttttgct gctcagcgca aaatcaaaga
0771 tgctgacctg ccgagtccgc agcaaaaact cgatatcctg caggaaacca tcgccttcct gacgcaatcg
0841 ggctatcagt ttatcggtat ggatcacttt gcccgtccgg atgacgagct ggcggtggcc cagcgtgaag
0911 gcgtgctgca tcgtaacttc cagggctaca ccactcaggg cgataccgat ctgctgggga tgggcgtttc
0981 cgccatcagc atgattggcg actgctacgc gcagaaccag aaagagttga agcagtacta tcagcaagtg
1051 gatgaacaag gcaatgcgct gtggcgtggt attgcgctaa cgcgtgatga ctgtattcgc cgcgatgtga
1121 ttaagtcgct catctgcaac ttccgtctgg attacgcccc tattgagaaa cagtgggatt tgcacttcgc
1191 tgattacttt gcggaagatc tcaagctgct cgccccgtta gcaaaagatg ggctggtgga tgtggatgag
1261 aagggaatac aggtgacggc gaaaggtcgc ttgctgatcc gcaacatttg catgtgcttt gatacctatc
1331 tgcgccagaa agcgcggatg cagcagttct ctcgggtgat ttaaATAGTG AATGGCGCTT CGTTTACAAA
1401 GTAGAAAACG AAAGCGCCAT CAATGTGCTG AGAACAAGAT TGCCTGATGC GCTGGGCAAC AAAACCTGTT
1471 GAAA
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