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PEC Original Annotations
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|
Essentiality
|
|
Class
|
essential
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|
References (PMID)
|
DNA Res. 1995;2(1):1-8.
Cloning and identification of the hemG gene encoding protoporphyrinogen oxidase (PPO) of Escherichia coli K-12.
Nishimura K, Nakayashiki T, Inokuchi H.
(
7788523
)
|
|
|
Deletion
|
OCR05
(D)
,
OCR05-12-1
(D)
,
OCR05-13
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
hemG
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
hemG
Search strains by all related name:
hemG b3850 ECK3842 JW3827 o181 yihB
|
General information (Go to Linear View: )
|
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Gene Name
|
hemG
|
|
Alternative name
|
b3850,ECK3842,JW3827,o181,yihB
|
|
Location, Length
|
4,032,631 - 4,033,176
(
+
)
;
86.92
min
;
546
(bp) ,
181
(aa)
|
|
Product
|
protoporphyrin oxidase, flavoprotein
|
|
Operon Name
|
pepQ-yigZ-trkH-hemG
|
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Note
|
protoporphyrin oxidase
|
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Function
|
enzyme; Biosynthesis of cofactors, carriers: Heme, porphyrin
|
|
Gene Ontology
|
GO:0004729
;
protoporphyrinogen oxidase activity ( hemG )
GO:0006118
;
electron transport ( hemG )
GO:0006779
;
porphyrin biosynthetic process ( hemG )
GO:0010181
;
FMN binding ( hemG )
GO:0016491
;
oxidoreductase activity ( hemG )
|
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PID
|
1790285
|
EC number
(KEGG Pathway)
|
1.3.3.4
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
hemG
(
EG11485
)
|
|
Number of removed
|
0 aa cleaved
|
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SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
HEMG_ECOLI
(
P27863
)
|
|
- Protein name
|
Protoporphyrinogen oxidase
|
|
- Synonyms
|
EC 1.3.3.4, PPO
|
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- Gene name
|
Name=hemG; OrderedLocusNames=b3850, c4797, z5372, ECs4778;
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MMBR References
|
DNA Res. 1995;2(1):1-8.
Cloning and identification of the hemG gene encoding protoporphyrinogen oxidase (PPO) of Escherichia coli K-12.
Nishimura K, Nakayashiki T, Inokuchi H.
(
7788523
)
|
Can J Microbiol. 1993;39(12):1155-61.
Nucleotide sequence of the hemG gene involved in the protoporphyrinogen oxidase activity of Escherichia coli K12.
Sasarman A, Letowski J, Czaika G, Ramirez V, Nead MA, Jacobs JM, Morais R.
(
7916647
)
|
J Gen Microbiol. 1979;113(2):297-303.
Mapping of a new hem gene in Escherichia coli K12.
Sasarman A, Chartrand P, Lavoie M, Tardif D, Proschek R, Lapointe C.
(
390093
)
|
Proc Natl Acad Sci U S A. 1996;93:2459-2463
Non-iron porphyrins cause tumbling to blue light by an Escherichia coli mutant defective in hemG.
Yang, H., A. Sasarman, H. Inokuchi, and J. Adler.
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| Sequences |
Amino acid
FASTA format
|
0001 MKTLILFSTR DGQTREIASY LASELKELGI QADVANVHRI EEPQWENYDR VVIGASIRYG HYHSAFQEFV
0071 KKHATRLNSM PSAFYSVNLV ARKPEKRTPQ TNSYARKFLM NSQWRPDRCA VIAGALRYPR YRWYDRFMIK
0141 LIMKMSGGET DTRKEVVYTD WEQVANFARE IAHLTDKPTL K
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AATGGATCCT GATTGCCAAC ATGCTGTTTG
-070 GTCGTCTCGA GGTCTTTACA TTGCTGGTGC TCTTTACCCC GACTTTCTGG CGTGAATGAT GGAGTAATAC
0001 gtgaaaacat taattctttt ctcaacaagg gacggacaaa cgcgcgagat tgcctcctac ctggcttcgg
0071 aactgaaaga actggggatc caggcggatg tcgccaatgt gcaccgcatt gaagaaccac agtgggaaaa
0141 ctatgaccgt gtggtcattg gtgcttctat tcgctatggt cactaccatt cagcgttcca ggaatttgtc
0211 aaaaaacatg cgacgcggct gaattcgatg ccgagcgcct tttactccgt gaatctggtg gcgcgcaaac
0281 cggagaagcg tactccacag accaacagct acgcgcgcaa gtttctgatg aactcgcaat ggcgtcccga
0351 tcgctgcgcg gtcattgccg gggcgctgcg ttacccacgt tatcgctggt acgaccgttt tatgatcaag
0421 ctgattatga agatgtcagg cggtgaaacg gatacgcgca aagaagttgt ctataccgat tgggagcagg
0491 tggcgaattt cgcccgagaa atcgcccatt taaccgacaa accgacgctg aaataaGCAT AAAGAATAAA
0561 AAATGCGCGG TCAGAAAATT ATTTTAAATT TCCTCTTGTC AGGCCGGAAT AACTCCCTAT AATGCGCCAC
0631 CACTGACACG GAACAA
|
