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PEC Original Annotations
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Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
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Deletion
|
OCR04
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
recQ
|
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Related strains
|
|
Strains Search
|
Search strains by gene name:
recQ
Search strains by all related name:
recQ b3822 ECK3816 JW5855 o610
|
General information (Go to Linear View: )
|
|
Gene Name
|
recQ
|
|
Alternative name
|
b3822,ECK3816,JW5855,o610
|
|
Location, Length
|
4,003,887 - 4,005,716
(
+
)
;
86.30
min
;
1830
(bp) ,
609
(aa)
|
|
Product
|
ATP-dependent DNA helicase
|
|
Operon Name
|
recQ
|
|
Note
|
GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006261 - DNA-dependent DNA replication; GO_process: GO:0006281 - DNA repair; GO_process: GO:0006310 - DNA recombination
|
|
Function
|
enzyme; DNA - replication, repair,restriction/modification
|
|
Gene Ontology
|
GO:0000166
;
nucleotide binding ( recQ )
GO:0003676
;
nucleic acid binding ( recQ )
GO:0003677
;
DNA binding ( recQ )
GO:0003824
;
catalytic activity ( recQ )
GO:0004003
;
ATP-dependent DNA helicase activity ( recQ )
GO:0004386
;
helicase activity ( recQ )
GO:0005524
;
ATP binding ( recQ )
GO:0005622
;
intracellular ( recQ )
GO:0006281
;
DNA repair ( recQ )
GO:0006310
;
DNA recombination ( recQ )
GO:0006974
;
response to DNA damage stimulus ( recQ )
GO:0008026
;
ATP-dependent helicase activity ( recQ )
GO:0008270
;
zinc ion binding ( recQ )
GO:0009432
;
SOS response ( recQ )
GO:0016787
;
hydrolase activity ( recQ )
GO:0044237
;
cellular metabolic process ( recQ )
|
|
PID
|
48994977
|
EC number
(KEGG Pathway)
|
3.6.1.-
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
recQ
(
EG10833
)
|
|
Number of removed
|
1 aa cleaved
|
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
RECQ_ECOLI
(
P15043
;
P76762
)
|
|
- Protein name
|
ATP-dependent DNA helicase recQ
|
|
- Synonyms
|
EC 3.6.1.-
|
|
- Gene name
|
Name=recQ; OrderedLocusNames=b3822;
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
recQ
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Structure Of The Recq Catalytic Core Bound To Atp-Gamma-S
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
ATP-dependent DNA helicase recQ
|
|
PSI-BLAST
|
ATP-dependent RNA helicase ded-1
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
ATP-dependent DNA helicase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
PROKAR_LIPOPROTEIN
|
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MMBR References
|
Mol Gen Genet. 1986;205(2):298-304.
The recQ gene of Escherichia coli K12: primary structure and evidence for SOS regulation.
Irino N, Nakayama K, Nakayama H.
(
3027506
)
|
J Bacteriol. 1995;177:1326-1335
DNA helicases in recombination and repair: construction of a Delta uvrD Delta helD Delta recQ mutant deficient in recombination and repair.
Mendonca, V. M., H. D. Klepin, and S. W. Matson.
|
Mol Gen Genet. 1984;195(3):474-80.
Isolation and genetic characterization of a thymineless death-resistant mutant of Escherichia coli K12: identification of a new mutation (recQ1) that blocks the RecF recombination pathway.
Nakayama H, Nakayama K, Nakayama R, Irino N, Nakayama Y, Hanawalt PC.
(
6381965
)
|
Mol Gen Genet. 1985;200(2):266-71.
The recQ gene of Escherichia coli K12: molecular cloning and isolation of insertion mutants.
Nakayama K, Irino N, Nakayama H.
(
2993821
)
|
J Mol Biol. 1988;200(3):427-38.
Generation of a detailed physical and genetic map of the ilv-metE-udp region of the Escherichia coli chromosome.
Aldea M, Maples VF, Kushner SR.
(
3294419
)
|
Science. 1992;257(5071):771-8.
Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.
Daniels DL, Plunkett G 3rd, Burland VD, Blattner FR.
(
1379743
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MAQAEVLNLE SGAKQVLQET FGYQQFRPGQ EEIIDTVLSG RDCLVVMPTG GGKSLCYQIP ALLLNGLTVV
0071 VSPLISLMKD QVDQLQANGV AAACLNSTQT REQQLEVMTG CRTGQIRLLY IAPERLMLDN FLEHLAHWNP
0141 VLLAVDEAHC ISQWGHDFRP EYAALGQLRQ RFPTLPFMAL TATADDTTRQ DIVRLLGLND PLIQISSFDR
0211 PNIRYMLMEK FKPLDQLMRY VQEQRGKSGI IYCNSRAKVE DTAARLQSKG ISAAAYHAGL ENNVRADVQE
0281 KFQRDDLQIV VATVAFGMGI NKPNVRFVVH FDIPRNIESY YQETGRAGRD GLPAEAMLFY DPADMAWLRR
0351 CLEEKPQGQL QDIERHKLNA MGAFAEAQTC RRLVLLNYFG EGRQEPCGNC DICLDPPKQY DGSTDAQIAL
0421 STIGRVNQRF GMGYVVEVIR GANNQRIRDY GHDKLKVYGM GRDKSHEHWV SVIRQLIHLG LVTQNIAQHS
0491 ALQLTEAARP VLRGESSLQL AVPRIVALKP KAMQKSFGGN YDRKLFAKLR KLRKSIADES NVPPYVVFND
0561 ATLIEMAEQM PITASEMLSV NGVGMRKLER FGKPFMALIR AHVDGDDEE
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CAGCATCCAG GATTACCCTC TCAGAGACTA
-070 AAAGCATTGC AGTTTCTCGC GCAGGCGCTG AAAATAGCGC CTGTTTTTAT TTCAGGCAAT CGGGGTGAAT
0001 gtggcgcagg cggaagtgtt gaatctggag tccggagcta aacaggtttt acaagaaacc tttggctacc
0071 aacagtttcg ccccggccag gaagaaatta tcgacactgt gctttccggc cgcgattgcc tcgtcgtcat
0141 gcccactggt ggcggaaaat ccctttgcta tcaaatccct gccttattgc taaacggcct taccgtggtt
0211 gtttcaccgc tgatttcgtt gatgaaagat caggtggatc aactgcaagc caacggcgtg gcggcggcgt
0281 gccttaactc gacgcaaacc cgcgaacagc aacttgaagt gatgacaggc tgccgcaccg ggcaaattcg
0351 tctgctttat atcgccccgg aacgcctgat gctggataac tttcttgagc atctggcgca ctggaatccg
0421 gtgttattag ccgttgatga agcgcactgt atctcccaat ggggccacga tttccgcccg gaatatgccg
0491 cgctcggtca gttgcgccag cggttcccga cgctgccgtt tatggcgctg accgccacag ccgacgacac
0561 cacgcgccag gatatcgtgc gcctgctggg gctgaacgat ccgctgattc aaatcagcag ttttgaccgt
0631 ccgaatattc gctacatgct gatggagaag ttcaaaccgc tcgatcagtt gatgcgctac gtgcaggaac
0701 agcgcggtaa gtcaggcatt atctactgca acagccgcgc gaaagtagaa gacaccgctg cgcgcctgca
0771 aagcaaggga attagcgcgg cggcctatca tgccgggctg gaaaataatg ttcgcgccga tgtgcaggaa
0841 aaattccagc gcgatgacct gcaaattgtg gtggcgacgg tggcgttcgg catgggcatc aataaaccaa
0911 acgttcgctt cgtggtccac tttgatattc cgcgcaatat cgaatcctat tatcaggaaa ccggacgcgc
0981 cgggcgtgat ggcctgcccg cggaagcgat gctgttttac gatccggctg atatggcgtg gctgcgccgt
1051 tgtctggaag agaagccgca ggggcagttg caggatatcg agcgccacaa actcaatgcg atgggcgcgt
1121 ttgccgaagc gcaaacttgc cgtcgtctgg tattgctgaa ctattttggc gaagggcgtc aggagccgtg
1191 cgggaactgc gatatctgcc tcgatccgcc gaaacagtac gacggttcaa ccgatgctca gattgccctt
1261 tccaccattg gtcgtgtgaa tcagcggttt gggatgggtt atgtggtgga agtgattcgt ggtgctaata
1331 accagcgtat ccgcgactat ggtcatgaca aactgaaagt ctatggcatg ggccgtgata aaagccatga
1401 acattgggtg agcgtgatcc gccagctgat tcacctcggc ctggtgacgc aaaatattgc ccagcattct
1471 gccctacaac tgacagaggc cgcgcgcccg gtgctgcgcg gcgaatcctc tttgcaactt gccgtgccgc
1541 gtatcgtggc gctcaaaccg aaagcgatgc agaaatcgtt cggcggcaac tatgatcgca aactgttcgc
1611 caaattacgc aaactgcgta aatcgatagc cgatgaaagt aatgtcccgc cgtacgtggt gtttaacgac
1681 gcaaccttga ttgagatggc tgaacagatg ccgatcaccg ccagcgaaat gctcagcgtt aacggcgttg
1751 ggatgcgcaa gctggaacgc tttggcaaac cgtttatggc gctgattcgt gcgcatgttg atggcgatga
1821 cgaagagtag TCAGCAGCAT AAAAAAGTGC CAGTATGAAG ACTCCGTAAA CGTTTCCCCC GCGAGTCAAA
1891 TGTATGTTGA TGTTATTTCT CACCGTCGCC ATGGTGCACA
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