|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
OCR03
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
cyaY
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
cyaY
Search strains by all related name:
cyaY b3807 ECK3801 JW3779 yifL yzcX
|
General information (Go to Linear View: )
|
|
Gene Name
|
cyaY
|
|
Alternative name
|
b3807,ECK3801,JW3779,yifL,yzcX
|
|
Location, Length
|
3,991,762 - 3,992,082
(
-
)
;
86.04
min
;
321
(bp) ,
106
(aa)
|
|
Product
|
iron-dependent inhibitor of iron-sulfur cluster formation; frataxin; iron-binding and oxidizing protein
|
|
Operon Name
|
cyaY
|
|
Note
|
iron-binding frataxin homolog; cyaY is expressed; neither knock-out nor overexpression of cyaY in Escherichia coli affects cellular iron content or sensitivity to oxidants; possibly involved in maintaining the intracellular iron pool in a soluble, non-toxic and bio-available form for biosynthetic pathways, while preventing the participation of iron in oxidative damage
|
|
Function
|
possible iron chaperone
|
|
Gene Ontology
|
GO:0005886
;
plasma membrane ( yifL )
GO:0016020
;
membrane ( yifL )
|
|
PID
|
1790239
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
CYAY_ECOLI
(
P27838
)
|
|
- Protein name
|
CyaY protein.
|
|
- Synonyms
|
|
|
- Gene name
|
Name=cyaY; OrderedLocusNames=b3807;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
cyaY
(
homologous genes of other bacterias
)
yzcX
(
homologous genes of other bacterias
)
yifL
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Solution Structure Of The Bacterial Frataxin Orthologue, Cyay
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Protein cyaY
|
|
PSI-BLAST
|
Protein cyaY
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
Chain A, Solution Structure Of The Bacterial Frataxin Orthologue, Cyay
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
|
| Sequences |
Amino acid
FASTA format
|
0001 MNDSEFHRLA DQLWLTIEER LDDWDGDSDI DCEINGGVLT ITFENGSKII INRQEPLHQV WLATKQGGYH
0071 FDLKGDEWIC DRSGETFWDL LEQAATQQAG ETVSFR
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cggatgaatc gtgccggaac gcagccgcag
-070 aggtgcaaac tttgaagccc tgaccccatg ccgctatact gccgccatca cttaaaaaca ggatacaaca
0001 atgaacgaca gtgaatttca tcgcctggct gatcaactct ggctgaccat tgaagaacgc ctggacgact
0071 gggatggcga cagcgatatc gactgcgaaa tcaacggcgg cgtactgacc attacctttg agaatggcag
0141 caaaatcatt atcaaccgcc aggagccgct gcaccaggta tggctggcaa ccaaacaggg cggctaccat
0211 tttgacctga aaggcgatga gtggatttgt gatcgcagcg gcgaaacctt ctgggatttg ctggaacagg
0281 cggcgacgca gcaggcgggt gaaacagtca gtttccgcta agattgcatg ccggataagc ctcgctttcc
0351 ggcacgttca tcacgaaaaa tattgctgta atagcggcgt atcgtgatcc tgattggcag gcggcatgtt
0421 a
|
