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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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Proc Natl Acad Sci U S A. 1976;73(6):1959-63.
Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho.
Das A, Court D, Adhya S.
(
132662
)
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Deletion
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OCR02-11
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
rho
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Related strains
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Strains Search
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Search strains by gene name:
rho
Search strains by all related name:
rho b3783 ECK3775 hdf JW3756 nitA nusD psuA rnsA rnsC sbaA sun tabC tsu
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General information (Go to Linear View: )
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Gene Name
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rho
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Alternative name
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b3783,ECK3775,hdf,JW3756,nitA,nusD,psuA,rnsA,rnsC,sbaA,sun,tabC,tsu
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Location, Length
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3,964,440 - 3,965,699
(
+
)
;
85.45
min
;
1260
(bp) ,
419
(aa)
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Product
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transcription termination factor
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Operon Name
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rhoL-rho
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Note
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transcription termination factor Rho; polarity suppressor; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0006350 - transcription
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Function
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factor; RNA synthesis, modification, DNA transcription
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Gene Ontology
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GO:0000166
;
nucleotide binding ( rho )
GO:0003676
;
nucleic acid binding ( rho )
GO:0003715
;
transcription termination factor activity ( rho )
GO:0003723
;
RNA binding ( rho )
GO:0004386
;
helicase activity ( rho )
GO:0005515
;
protein binding ( rho )
GO:0005524
;
ATP binding ( rho )
GO:0005624
;
membrane fraction ( rho )
GO:0006350
;
transcription ( rho )
GO:0006353
;
transcription termination ( rho )
GO:0006355
;
regulation of transcription, DNA-dependent ( rho )
GO:0015078
;
hydrogen ion transmembrane transporter activity ( rho )
GO:0016469
;
proton-transporting two-sector ATPase complex ( rho )
GO:0016787
;
hydrolase activity ( rho )
GO:0017111
;
nucleoside-triphosphatase activity ( rho )
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PID
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1790217
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EC number
(KEGG Pathway)
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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rho
(
EG10845
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
[
1
more]
)
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Entry name(Acc.no)
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RHO_ECOLI
(
P03002
;
Q48357
)
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- Protein name
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Transcription termination factor rho.
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- Synonyms
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- Gene name
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OrderedLocusNames=b3783, c4702, z5293, ECs4716, SF3856, S3903;
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MMBR References
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Proc Natl Acad Sci U S A. 1977;74:1162-1166
Isolation and characterization of conditional-lethal rho mutants of Escherichia coli.
Inoko, H., K. Shigesada, and M. Imai.
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J Bacteriol. 1985;161(2):799-802.
Thioredoxin is the bacterial protein encoded by fip that is required for filamentous bacteriophage f1 assembly.
Lim CJ, Haller B, Fuchs JA.
(
3881414
)
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Mol Gen Genet. 1983;191(3):347-52.
Molecular characterization of ilvC specialized transducing phages of Escherichia coli K-12.
Baylor NW, Williams AL, Cofie N.
(
6226847
)
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J Biol Chem. 1996;271:25369-25374
The antibiotic bicyclomycin affects the secondary RNA binding site of Escherichia coli transcription termination factor Rho.
Magyar, A., X. Zhang, H. Kohn, and W. R. Widger.
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J Bacteriol. 1986;166(3):945-58.
Autogenous regulation of the gene for transcription termination factor rho in Escherichia coli: localization and function of its attenuators.
Matsumoto Y, Shigesada K, Hirano M, Imai M.
(
2423505
)
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J Mol Biol. 1995;254(5):815-37.
Structural and functional dissections of transcription termination factor rho by random mutagenesis.
Miwa Y, Horiguchi T, Shigesada K.
(
7500353
)
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Nucleic Acids Res. 1983;11:3531-3545
The nucleotide sequence of the rho gene of E. coli K-12.
Pinkham, J. L., and T. Platt.
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J Biol Chem. 1996;271:21597-21603
Rho-dependent termination of transcription is governed primarily by the upstream Rho utilization (rut) sequences of a terminator.
Richardson, L. V., and J. P. Richardson.
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J Virol. 1980;35(3):775-89.
Role of the host cell in bacteriophage T4 development. II. Characterization of host mutants that have pleiotropic effects on T4 growth.
Stitt BL, Revel HR, Lielausis I, Wood WB.
(
6999171
)
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J Bacteriol. 1991;173(2):655-63.
A novel rho promoter::Tn10 mutation suppresses and ftsQ1(Ts) missense mutation in an essential Escherichia coli cell division gene by a mechanism not involving polarity suppression.
Storts DR, Markovitz A.
(
1846147
)
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J Bacteriol. 1982;151(3):1637-40.
Relative map location of the rep and rho genes of Escherichia coli.
Tessman I, Fassler JS, Bennett DC.
(
6286604
)
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Mol Gen Genet. 1981;182(3):462-70.
Genetical and structural analysis of a group of lambda ilv and lambda rho transducing phages.
Uzan M, Favre R, Gallay E, Caro L.
(
6272063
)
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J Mol Biol. 1982;162(2):283-98.
Localization and regulation of the structural gene for transcription-termination factor rho of Escherichia coli.
Brown S, Albrechtsen B, Pedersen S, Klemm P.
(
6219230
)
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J Mol Biol. 1988;200(3):427-38.
Generation of a detailed physical and genetic map of the ilv-metE-udp region of the Escherichia coli chromosome.
Aldea M, Maples VF, Kushner SR.
(
3294419
)
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Mol Gen Genet. 1984;193(2):205-9.
Location of the rho gene and characterization of lambda ilv-gal derivatives of lambda ilv-rho bacteriophage.
Calhoun DH, Traub L, Wallen JW, Gray JE, Guterman SK.
(
6319959
)
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Science. 1992;257(5071):771-8.
Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.
Daniels DL, Plunkett G 3rd, Burland VD, Blattner FR.
(
1379743
)
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Proc Natl Acad Sci U S A. 1976;73:1959-1963
Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho.
Das, A., D. L. Court, and S. Adhya.
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| Sequences |
Amino acid
FASTA format
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0001 MNLTELKNTP VSELITLGEN MGLENLARMR KQDIIFAILK QHAKSGEDIF GDGVLEILQD GFGFLRSADS
0071 SYLAGPDDIY VSPSQIRRFN LRTGDTISGK IRPPKEGERY FALLKVNEVN FDKPENARNK ILFENLTPLH
0141 ANSRLRMERG NGSTEDLTAR VLDLASPIGR GQRGLIVAPP KAGKTMLLQN IAQSIAYNHP DCVLMVLLID
0211 ERPEEVTEMQ RLVKGEVVAS TFDEPASRHV QVAEMVIEKA KRLVEHKKDV IILLDSITRL ARAYNTVVPA
0281 SGKVLTGGVD ANALHRPKRF FGAARNVEEG GSLTIIATAL IDTGSKMDEV IYEEFKGTGN MELHLSRKIA
0351 EKRVFPAIDY NRSGTRKEEL LTTQEELQKM WILRKIIHPM GEIDAMEFLI NKLAMTKTND DFFEMMKRS
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 AGACATGAGT CGATGACCGT AAACAGGCAT
-070 GGATGATCCT GCCATACCAT TCACAACATT AAGTTCGAGA TTTACCCCAA GTTTAAGAAC TCACACCACT
0001 atgaatctta ccgaattaaa gaatacgccg gtttctgagc tgatcactct cggcgaaaat atggggctgg
0071 aaaacctggc tcgtatgcgt aagcaggaca ttatttttgc catcctgaag cagcacgcaa agagtggcga
0141 agatatcttt ggtgatggcg tactggagat attgcaggat ggatttggtt tcctccgttc cgcagacagc
0211 tcctacctcg ccggtcctga tgacatctac gtttccccta gccaaatccg ccgtttcaac ctccgcactg
0281 gtgataccat ctctggtaag attcgcccgc cgaaagaagg tgaacgctat tttgcgctgc tgaaagttaa
0351 cgaagttaac ttcgacaaac ctgaaaacgc ccgcaacaaa atcctctttg agaacttaac cccgctgcac
0421 gcaaactctc gtctgcgtat ggaacgtggt aacggttcta ctgaagattt aactgctcgc gtactggatc
0491 tggcatcacc tatcggtcgt ggtcagcgtg gtctgattgt ggcaccgccg aaagccggta aaaccatgct
0561 gctgcagaac attgctcaga gcattgctta caaccacccg gattgtgtgc tgatggttct gctgatcgac
0631 gaacgtccgg aagaagtaac cgagatgcag cgtctggtaa aaggtgaagt tgttgcttct acctttgacg
0701 aacccgcatc tcgccacgtt caggttgcgg aaatggtgat cgagaaggcc aaacgcctgg ttgagcacaa
0771 gaaagacgtt atcattctgc tcgactccat cactcgtctg gcgcgcgctt acaacaccgt tgttccggcg
0841 tcaggtaaag tgttgaccgg tggtgtggat gccaacgccc tgcatcgtcc gaaacgcttc tttggtgcgg
0911 cgcgtaacgt ggaagagggc ggcagcctga ccattatcgc gacggcgctt atcgataccg gttctaaaat
0981 ggacgaagtt atctacgaag agtttaaagg tacaggcaac atggaactgc acctctctcg taagatcgct
1051 gaaaaacgcg tcttcccggc tatcgactac aaccgttctg gtacccgtaa agaagagctg ctcacgactc
1121 aggaagaact gcagaaaatg tggatcctgc gcaaaatcat tcacccgatg ggcgaaatcg atgcaatgga
1191 attcctcatt aataaactgg caatgaccaa gaccaatgac gatttcttcg aaatgatgaa acgctcataa
1261 ATTTGTCTTA TGCCAAAAAC GCCACGTGTT TACGTGGCGT TTTGCTTTTA TATCTGTAAT CTTAATGCCG
1331 CGCTGGCGAT GTTAGGAAAA TTCCTGGAAT
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