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PEC Original Annotations
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Essentiality
|
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Class
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non-essential
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References (PMID)
|
|
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Deletion
|
OCR02-6
(D)
,
DE(ilvG-ilvE)2130
|
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Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
ilvM
|
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Related strains
|
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Strains Search
|
Search strains by gene name:
ilvM
Search strains by all related name:
ilvM b3769 ECK3761 JW3742
|
General information (Go to Linear View: )
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Gene Name
|
ilvM
|
|
Alternative name
|
b3769,ECK3761,JW3742
|
|
Location, Length
|
3,950,224 - 3,950,487
(
+
)
;
85.14
min
;
264
(bp) ,
87
(aa)
|
|
Product
|
acetolactate synthase II, small subunit
|
|
Operon Name
|
ilvLXG_1G_2MEDA
|
|
Note
|
acetolactate synthase II, valine insensitive, small subunit
|
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Function
|
enzyme; Amino acid biosynthesis: Isoleucine, Valine
|
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Gene Ontology
|
GO:0000287
;
magnesium ion binding ( ilvM )
GO:0003984
;
acetolactate synthase activity ( ilvM )
GO:0008652
;
amino acid biosynthetic process ( ilvM )
GO:0009082
;
branched chain family amino acid biosynthetic process ( ilvM )
GO:0016740
;
transferase activity ( ilvM )
|
|
PID
|
1790204
|
EC number
(KEGG Pathway)
|
2.2.1.6
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
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EcoGene
|
ilvM
(
EG10501
)
|
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Number of removed
|
0 aa cleaved
|
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
ILVM_ECOLI
(
P13048
;
P78269
)
|
|
- Protein name
|
Acetolactate synthase isozyme II small subunit
|
|
- Synonyms
|
EC 2.2.1.6, AHAS-II, Acetohydroxy-acid synthase II small subunit, ALS-II
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- Gene name
|
Name=ilvM; OrderedLocusNames=b3769, c4691, SF3844, S3915;
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MMBR References
|
J Bacteriol. 1992;174:4871-4877
Multiple transcripts encoded by the ilvGMEDA gene cluster of Escherichia coli K-12.
Huang, F., G. Coppola, and D. H. Calhoun.
|
Nucleic Acids Res. 1987;15:2137-2155
The complete nucleotide sequence of the ilvGMEDA operon of Escherichia coli K-12.
Lawther, R. P., R. C. Wek, J. M. Lopes, R. Pereira, B. E. Taillon, and G. W. Hatfield.
|
Nucleic Acids Res. 1986;14:2779-2798
Analysis and comparison of the internal promoter, pE, of the ilvGMEDA operon from Escherichia coli K-12 and Salmonella typhimurium.
Lopes, J. M., and R. P. Lawther.
|
J Bacteriol. 1987;169(2):600-4.
Effects of deletion and insertion mutations in the ilvM gene of Escherichia coli.
Lu MF, Umbarger HE.
(
3027038
)
|
Nucleic Acids Res. 1986;14:2763-2777
Examination of the internal promoter, PE, in the ilvGMEDA operon of E. coli K-12.
Wek, R. C., and G. W. Hatfield.
|
Gene. 1987;56(2-3):185-98.
The complete nucleotide sequence of the ilvGMEDA cluster of Escherichia coli K-12.
Cox JL, Cox BJ, Fidanza V, Calhoun DH.
(
3315862
)
|
Science. 1992;257(5071):771-8.
Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.
Daniels DL, Plunkett G 3rd, Burland VD, Blattner FR.
(
1379743
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MMQHQVNVSA RFNPETLERV LRVVRHRGFH VCSMNMAAAS DAQNINIELT VASPRSVDLL FSQLNKLVDV
0071 AHVAICQSTT TSQQIRA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ATGGGCCATA CCTGCTTCAT GTCTCAATCG
-070 ACGAACTTGA GAACGTCTGG CCGCTGGTGC CGCCTGGCGC CAGTAATTCA GAAATGTTGG AGAAATTATC
0001 atgatgcaac atcaggtcaa tgtatcggct cgcttcaatc cagaaacctt agaacgtgtt ttacgcgtgg
0071 tgcgtcatcg tggtttccac gtctgctcaa tgaatatggc cgccgccagc gatgcacaaa atataaatat
0141 cgaattgacc gttgccagcc cacggtcggt cgacttactg tttagtcagt taaataaact ggtggacgtc
0211 gcacacgttg ccatctgcca gagcacaacc acatcacaac aaatccgcgc ctgaGCGCAA AAGGAATATA
0281 AAAATGACCA CGAAGAAAGC TGATTACATT TGGTTCAATG GGGAGATGGT TCGCTGGGAA GACGCGAAGG
0351 TGCATGTGAT GTCG
|
