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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCR02-6
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
ilvG
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Related strains
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Strains Search
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Search strains by gene name:
ilvG
Search strains by all related name:
ilvG b3767 b3768 b4488 ECK3760 ilvG_1 ilvO JW3740 JW3741 o221b o327
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General information (Go to Linear View: )
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Gene Name
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ilvG
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Alternative name
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b3767,b3768,b4488,ECK3760,ilvG_1,ilvO,JW3740,JW3741,o221b,o327
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Location, Length
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3,948,583 - 3,950,227
(
+
)
;
85.10
min
;
1645
(bp) ,
547
(aa)
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Product
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Operon Name
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Note
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pseudogene, acetohydroxy acid synthase II; acetolactate synthase II, large subunit, cryptic, interrupted
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Function
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Gene Ontology
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GO:0000287
;
magnesium ion binding ( ilvG )
GO:0003824
;
catalytic activity ( ilvG )
GO:0003984
;
acetolactate synthase activity ( ilvG )
GO:0005515
;
protein binding ( ilvG )
GO:0008652
;
amino acid biosynthetic process ( ilvG )
GO:0009082
;
branched chain family amino acid biosynthetic process ( ilvG )
GO:0016740
;
transferase activity ( ilvG )
GO:0030976
;
thiamin pyrophosphate binding ( ilvG )
GO:0046872
;
metal ion binding ( ilvG )
GO:0050660
;
FAD binding ( ilvG )
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PID
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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ILVG_ECOLI
(
P00892
;
P76749
)
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- Protein name
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Acetolactate synthase isozyme II large subunit
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- Synonyms
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EC 2.2.1.6, AHAS-II, Acetohydroxy-acid synthase II large subunit, ALS-II
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- Gene name
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Name=ilvG; OrderedLocusNames=b3767;
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MMBR References
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J Bacteriol. 1985;162(2):598-606.
Physical analysis of deletion mutations in the ilvGEDA operon of Escherichia coli K-12.
Driver RP, Lawther RP.
(
2985538
)
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J Bacteriol. 1980;142(2):556-67.
Location of the multivalent control site for the ilvEDA operon of Escherichia coli.
Gayda DJ, Leathers TD, Noti JD, Smith FJ, Smith JM, Subrahmanyam CS, Umbarger HE.
(
6247324
)
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Genet Res. 1962;3:448-460.
Valine-resistant mutants of Escherichia coli K-12.
Glover, S. W.
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J Bacteriol. 1982;149(3):1071-81.
Physical and genetic localization of ilv regulatory sites in lambda ilv bacteriophages.
Gray JE, Bennett DC, Umbarger HE, Calhoun DH.
(
6277848
)
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J Bacteriol. 1992;174:4871-4877
Multiple transcripts encoded by the ilvGMEDA gene cluster of Escherichia coli K-12.
Huang, F., G. Coppola, and D. H. Calhoun.
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Nucleic Acids Res. 1979;7:2289-2301
The nucleotide sequence preceding and including the beginning of the ilvE gene of the ilvGEDA operon of Escherichia coli.
Lawther, R. P., B. Nichols, G. Zurawski, and G. W. Hatfield.
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Proc Natl Acad Sci U S A. 1981;78:922-925
Molecular basis of valine resistance in Escherichia coli K-12.
Lawther, R. P., D. H. Calhoun, C. W. Adams, C. A. Hauser, J. E. Gray, and G. W. Hatfield.
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J Bacteriol. 1982;149(1):294-8.
DNA sequence fine-structure analysis of ilvG (IlvG+) mutations of Escherichia coli K-12.
Lawther RP, Calhoun DH, Gray J, Adams CW, Hauser CA, Hatfield GW.
(
7033211
)
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Proc Natl Acad Sci U S A. 1980;77:1862-1866
Multivalent translational control of transcription termination at attenuator of ilvGEDA operon of Escherichia coli K-12.
Lawther, R. P., and G. W. Hatfield.
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Nucleic Acids Res. 1987;15:2137-2155
The complete nucleotide sequence of the ilvGMEDA operon of Escherichia coli K-12.
Lawther, R. P., R. C. Wek, J. M. Lopes, R. Pereira, B. E. Taillon, and G. W. Hatfield.
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J Bacteriol. 1987;169(2):600-4.
Effects of deletion and insertion mutations in the ilvM gene of Escherichia coli.
Lu MF, Umbarger HE.
(
3027038
)
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Proc Natl Acad Sci U S A. 1980;77:1823-1827
Nucleotide sequence of ivlGEDA operon attenuator region of Escherichia coli.
Nargang, F. E., C. S. Subrahmanyam, and H. E. Umbarger.
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Gene. 1980;12(1-2):165-70.
The ilvG gene is expressed in Escherichia coli K-12.
Berg CM, Shaw KJ, Berg DE.
(
6260586
)
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J Bacteriol. 1997;179:2086-2088
Growth rate-related regulation of the ilvGMEDA operon of Escherichia coli K-12 is a consequence of the polar frameshift mutation in the ilvG gene of this strain.
Parekh, B. S., and G. W. Hatfield.
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J Bacteriol. 1980;142(2):547-55.
Physical location of the ilvO determinant in Escherichia coli K-12 deoxyribonucleic acid.
Subrahmanyam CS, McCorkle GM, Umbarger HE.
(
6155372
)
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J Bacteriol. 1980;144(1):279-90.
Regulation of ilvEDA expression occurs upstream of ilvG in Escherichia coli: additional evidence for an ilvGEDA operon.
Subrahmanyam CS, Noti JD, Umbarger HE.
(
6252193
)
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Mol Gen Genet. 1981;182(3):462-70.
Genetical and structural analysis of a group of lambda ilv and lambda rho transducing phages.
Uzan M, Favre R, Gallay E, Caro L.
(
6272063
)
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FEMS Microbiol Lett. 1995;131(2):167-72.
Silent genes in bacteria: the previously designated 'cryptic' ilvHI locus of 'Salmonella typhimurium LT2' is active in natural isolates.
Burns DM, Burger MJ, Beacham IR.
(
7557326
)
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J Mol Biol. 1988;200(3):427-38.
Generation of a detailed physical and genetic map of the ilv-metE-udp region of the Escherichia coli chromosome.
Aldea M, Maples VF, Kushner SR.
(
3294419
)
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Gene. 1987;56(2-3):185-98.
The complete nucleotide sequence of the ilvGMEDA cluster of Escherichia coli K-12.
Cox JL, Cox BJ, Fidanza V, Calhoun DH.
(
3315862
)
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Science. 1992;257(5071):771-8.
Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.
Daniels DL, Plunkett G 3rd, Burland VD, Blattner FR.
(
1379743
)
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| Sequences |
Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 GTCCGGGGGT TTTTTTTGAC CTTAAAAACA
-070 TAACCGAGGA GCAGACAATG AATAACAGCA CAAAATTCTG TTTCTCAAGA TTCAGGACGG GGAACTAACT
0001 atgaatggcg cacagtgggt ggtacatgcg ttgcgggcac agggtgtgaa caccgttttc ggttatccgg
0071 gtggcgcaat tatgccggtt tacgatgcat tgtatgacgg cggcgtggag cacttgctat gccgacatga
0141 gcagggtgcg gcaatggcgg ctatcggtta tgctcgtgct accggcaaaa ctggcgtatg tatcgccacg
0211 tctggtccgg gcgcaaccaa cctgataacc gggcttgcgg acgcactgtt agattccatc cctgttgttg
0281 ccatcaccgg tcaagtgtcc gcaccgttta tcggcactga cgcatttcag gaagtggatg tcctgggatt
0351 gtcgttagcc tgtaccaagc acagctttct ggtgcagtcg ctggaagagt tgccgcgcat catggctgaa
0421 gcattcgacg ttgcctgctc aggtcgtcct ggtccggttc tggtcgatat cccaaaagat atccagttag
0491 ccagcggtga cctggaaccg tggttcacca ccgttgaaaa cgaagtgact ttcccacatg ccgaagttga
0561 gcaagcgcgc cagatgctgg caaaagcgca aaaaccgatg ctgtacgttg gcggtggcgt gggtatggcg
0631 caggcagttc cggctttgcg tgaatttctc gctgccacaa aaatgcctgc cacctgtacg ctgaaagggc
0701 tgggcgcagt agaagcagat tatccgtact atctgggcat gctggggatg cacggcacca aagcggcaaa
0771 cttcgcggtg caggagtgtg acctgctgat cgccgtgggc gcacgttttg atgaccgggt gaccggcaaa
0841 ctgaacacct tcgcgccaca cgccagtgtt atccatatgg atatcgaccc ggcagaaatg aacaagctgc
0911 gtcaggcaca tgtggcatta caaggtgatt taaatgctct gttaccagca ttacagcagc cgttaaatca
0981 atgactggca gcaacactgc gcgcagctgc gtgatgaaca ttcctggcgt tacgaccatc ccggtgacgc
1051 tatctacgcg ccgttgttgt taaaacaact gtcggatcgt aaacctgcgg attgcgtcgt gaccacagat
1121 gtggggcagc accagatgtg ggctgcgcag cacatcgccc acactcgccc ggaaaatttc atcacctcca
1191 gcggtttagg taccatgggt tttggtttac cggcggcggt tggcgcacaa gtcgcgcgac cgaacgatac
1261 cgttgtctgt atctccggtg acggctcttt catgatgaat gtgcaagagc tgggcaccgt aaaacgcaag
1331 cagttaccgt tgaaaatcgt cttactcgat aaccaacggt tagggatggt tcgacaatgg cagcaactgt
1401 tttttcagga acgatacagc gaaaccaccc ttactgataa ccccgatttc ctcatgttag ccagcgcctt
1471 cggcatccat ggccaacaca tcacccggaa agaccaggtt gaagcggcac tcgacaccat gctgaacagt
1541 gatgggccat acctgcttca tgtctcaatc gacgaacttg agaacgtctg gccgctggtg ccgcctggcg
1611 ccagtaattc agaaatgttg gagaaattat catgaTGCAA CATCAGGTCA ATGTATCGGC TCGCTTCAAT
1681 CCAGAAACCT TAGAACGTGT TTTACGCGTG GTGCGTCATC GTGGTTTCCA CGTCTGCTCA ATGAA
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