MG1655
W3110
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Gene Report : hdfR
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion OCR01,2-3 (AK4-14 / BK5-14) (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  hdfR
Related strains
     Strains Search Search strains by gene name:  hdfR   Search strains by all related name:  hdfR apeR? b3762 b3763 b4480 ECK3756 f133 JW5607 yifA yifD

General information  (Go to Linear View:)
 Gene Name hdfR  
 Alternative name apeR?,b3762,b3763,b4480,ECK3756,f133,JW5607,yifA,yifD  
 Location, Length 3,945,151 - 3,945,990 (  -  ) ;   85.03 min ; 840 (bp) ,   279 (aa) Go to Linear View
 Product DNA-binding transcriptional regulator  
 Operon Name hdfR  
 Note transcriptional regulator of the flhDC operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0006350 - transcription  
 Function 2.2.2 information transfer; RNA related; transcription related,3.1.2.3 regulation; type of regulation; transcriptional level; repressor,3.3.1 regulation; genetic unit regulated; operon,7.1 location of gene products; cytoplasm  
 Gene Ontology GO:0003677 ; DNA binding ( hdfR )
GO:0003700 ; transcription factor activity ( hdfR )
GO:0006350 ; transcription ( hdfR )
GO:0006355 ; regulation of transcription, DNA-dependent ( hdfR )
GO:0045892 ; negative regulation of transcription, DNA-dependent ( hdfR )
 PID 48994962  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) HDFR_ECOLI ( P27826 ; P22788; Q9KHQ8 )
    -  Protein name HTH-type transcriptional regulator hdfR  
    -  Synonyms H-NS-depdendent flhDC regulator  
    -  Gene name OrderedLocusNames=b3762/b3763, SF3839, S3921;  

 Linear View (Whole Mode)
View Location
   3935.0  –  3960.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP hdfR (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, The Crystal Structure Of Probable Transcriptional Regulator Pa0477 From Pseudomonas Aeruginosa  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST HTH-type transcriptional regulator hdfR (H-NS-dependent flhDC regulator)  
         PSI-BLAST HTH-type transcriptional regulator hdfR
    nr     (database updated : 2007.02.20 )
         BLAST transcriptional regulator HdfR [Shigella flexneri 2a str. 301]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    HTH_LYSR_FAMILY     

Other Cross-Reference
    COG COG0583K 
    EcoCyc hdfR 

MMBR References
J Biol Chem. 1983;258:9963-9967
A trans-acting regulatory mutation that causes overproduction of phosphatidylserine synthase in Escherichia coli.
Sparrow, C. P., and C. R. Raetz.
Gene. 1991;97(1):21-7.
Sequence and transcriptional activity of the Escherichia coli K-12 chromosome region between rrnC and ilvGMEDA.
Coppola G, Huang F, Riley J, Cox JL, Hantzopoulos P, Zhou LB, Calhoun DH. ( 1995430 )

Sequences
Amino acid
FASTA format
0001 MDTELLKTFL EVSRTRHFGR AAESLYLTQS AVSFRIRQLE NQLGVNLFTR HRNNIRLTAA GEKLLPYAET 
0071 LMSTWQAARK EVAHTSRHNE FSIGASASLW ECMLNQWLGR LYQNQDAHTG LQFEARIAQR QSLVKQLHER 
0141 QLDLLITTEA PKMDEFSSQL LGYFTLALYT SAPSKLKGDL NYLRLEWGPD FQQHEAGLIG ADEVPILTTS 
0211 SAELAQQQIA MLNGCTWLPV SWARKKGGLH TVVDSTTLSR PLYAIWLQNS DKNALIRDLL KINVLDEVY

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             tttgaccgag ctagttatgg cgcggagtat 
-070 tagttacgct tgacagagtg taaaacaaaa catttaaatc ataacgacaa ataattttgc ggagagcact 
0001 gtggatacgg aattgttaaa aactttcctg gaagttagcc gaacgcgtca ctttggtcga gcggctgaat 
0071 cgctctatct gacccagtca gcagtgagct ttcgaatcag acaactggaa aatcaactgg gtgtgaacct 
0141 tttcacccgc cacagaaaca atatccgttt aaccgctgcc ggtgaaaaac tactgcctta tgcagaaacg 
0211 ctcatgagca cctggcaggc cgcccgtaag gaggtggcgc atacctcacg acataacgag ttttctatcg 
0281 gtgccagcgc ctcgttgtgg gaatgtatgc ttaatcagtg gctgggacgc ttgtatcaaa atcaggatgc 
0351 ccatacaggc ttacagttcg aagcgcgaat tgcccaacgg cagtctctgg taaaacagct gcatgaacgc 
0421 cagcttgatc ttcttattac cactgaagcg cccaaaatgg acgaatttag tagtcagttg ctgggatatt 
0491 tcactttagc gctttatacc agtgcccctt caaaactaaa gggagatctt aattatctgc gacttgagtg 
0561 ggggccagat tttcaacagc atgaggcagg tttgatcggt gctgacgaag tgcccattct gacaaccagt 
0631 tctgctgaac tggcacagca acagattgcg atgcttaatg gttgcacctg gctacccgtc agctgggcgc 
0701 gtaaaaaagg cggcctgcat accgttgtcg atagcacaac actttcacgg ccgctttatg ccatatggct 
0771 gcaaaatagc gataaaaatg cgttgattcg cgatcttttg aaaattaacg tgctggatga agtgtattaa 
0841 tatgaatggc tggcaaggat gccggtagaa ggatttactt cggagagggt tatttcagat aaaaaaaatc 
0911 cttagctttc gctaaggatg atttctggca