MG1655
W3110
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Gene Report : rbsR
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Biol Chem. 1999;274(20):14006-11.
A mutated PtsG, the glucose transporter, allows uptake of D-ribose.
Oh H, Park Y, Park C. ( 10318813 )
     Deletion OCR01-1 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  rbsR
Related strains
     Strains Search Search strains by gene name:  rbsR   Search strains by all related name:  rbsR b3753 ECK3747 JW3732 o330

General information  (Go to Linear View:)
 Gene Name rbsR  
 Alternative name b3753,ECK3747,JW3732,o330  
 Location, Length 3,936,250 - 3,937,242 (  +  ) ;   84.84 min ; 993 (bp) ,   330 (aa) Go to Linear View
 Product DNA-binding transcriptional repressor of ribose metabolism  
 Operon Name rbsDACBKR  
 Note regulator for rbs operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription  
 Function regulator; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0003677; DNA binding ( rbsR )
GO:0003700; transcription factor activity ( rbsR )
GO:0005515; protein binding ( rbsR )
GO:0005622; intracellular ( rbsR )
GO:0006350; transcription ( rbsR )
GO:0006355; regulation of transcription, DNA-dependent ( rbsR )
 PID 1790194  
 EC number
  (KEGG Pathway)
 
 
Verified Protein Starts (data compiled from literature and appropriate citations are available from EcoGene)
     EcoGene rbsR ( EG10819 )  
    Number of removed 1 aa cleaved  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) RBSR_ECOLI ( P25551 )
    -  Protein name Ribose operon repressor.  
    -  Synonyms  
    -  Gene name OrderedLocusNames=b3753, c4681, z5254, ECs4695, SF3836, S3931;  

 Linear View (Whole Mode)
View Location
   3925.0  –  3950.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP rbsR (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Purine Repressor-Hypoxanthine-Purf-Operator Complex  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Ribose operon repressor  
         PSI-BLAST HTH-type transcriptional repressor purR (Purine nucleotide synthesis repressor)
    nr     (database updated : 2007.02.20 )
         BLAST regulator for rbs operon [Escherichia coli UTI89]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    HTH_LACI_FAMILY     

Other Cross-Reference
    COG COG1609K 
    EcoCyc rbsR 

MMBR References
J Bacteriol. 1984;158(2):665-73.
D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport.
Lopilato JE, Garwin JL, Emr SD, Silhavy TJ, Beckwith JR. ( 6327616 )

Sequences
Amino acid
FASTA format
0001 MATMKDVARL AGVSTSTVSH VINKDRFVSE AITAKVEAAI KELNYAPSAL ARSLKLNQTH TIGMLITAST 
0071 NPFYSELVRG VERSCFERGY SLVLCNTEGD EQRMNRNLET LMQKRVDGLL LLCTETHQPS REIMQRYPTV 
0141 PTVMMDWAPF DGDSDLIQDN SLLGGDLATQ YLIDKGHTRI ACITGPLDKT PARLRLEGYR AAMKRAGLNI 
0211 PDGYEVTGDF EFNGGFDAMR QLLSHPLRPQ AVFTGNDAMA VGVYQALYQA ELQVPQDIAV IGYDDIELAS 
0281 FMTPPLTTIH QPKDELGELA IDVLIHRITQ PTLQQQRLQL TPILMERGSA 

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             CCATGCTGCC GCTGCGATTG CCGTAACACG 
-070 TAAAGGCGCA CAACCTTCCG TACCGTGGCG TGAAGAGATC GACGCATTTT TAGACAGGCA GAGGTGACGC 
0001 ttggctacaa tgaaagatgt tgcccgcctg gcgggcgttt ctacctcaac agtttctcac gttatcaata 
0071 aagatcgctt cgtcagtgaa gcgattaccg ccaaagttga agcggcgatt aaagaactca attacgcgcc 
0141 atcagctctg gcgcgtagcc tcaaactcaa tcaaacacat accattggca tgttgatcac tgccagtacc 
0211 aatcctttct attcagaact ggtgcgtggc gttgaacgca gctgcttcga acgcggttat agtctcgtcc 
0281 tttgcaatac cgaaggcgat gaacagcgga tgaatcgcaa tctggaaacg ctgatgcaaa aacgcgttga 
0351 tggcttgctg ttactgtgca ccgaaacgca tcaaccttcg cgtgaaatca tgcaacgtta tccgacagtg 
0421 cctactgtga tgatggactg ggctccgttc gatggcgaca gcgatcttat tcaggataac tcgttgctgg 
0491 gcggagactt agcaacgcaa tatctgatcg ataaaggtca tacccgtatc gcctgtatta ccggcccgct 
0561 ggataaaact ccggcgcgcc tgcggttgga aggttatcgg gcggcgatga aacgtgcggg tctcaacatt 
0631 cctgatggct atgaagtcac tggtgatttt gaatttaacg gcgggtttga cgctatgcgc caactgctat 
0701 cacatccgct gcgtcctcag gccgtcttta ccggaaatga cgctatggct gttggcgttt accaggcgtt 
0771 atatcaggca gagttacagg ttccgcagga tatcgcggtg attggctatg acgatatcga actggcaagc 
0841 tttatgacgc caccattaac cactatccac caaccgaaag atgaactggg ggagctggcg attgatgtac 
0911 tcatccatcg gataacccag ccgacccttc agcaacaacg attacaactt actccgattc tgatggaacg 
0981 cggttcggct tagATTTACG CTGTCTTTTG ATCAAATTAT TACCATCGGT TGTTTTCAGA AGCATGAACA 
1051 TTGCTGCTGA AGCAACAGTA ATAATGCCCA TTGTGATAAA CGT