MG1655
W3110
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Gene Report : rbsK
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Biol Chem. 1999;274(20):14006-11.
A mutated PtsG, the glucose transporter, allows uptake of D-ribose.
Oh H, Park Y, Park C. ( 10318813 )
     Deletion OCR01-1 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  rbsK
Related strains
     Strains Search Search strains by gene name:  rbsK   Search strains by all related name:  rbsK b3752 ECK3746 JW3731 o309 rbsP

General information  (Go to Linear View:)
 Gene Name rbsK  
 Alternative name b3752,ECK3746,JW3731,o309,rbsP  
 Location, Length 3,935,317 - 3,936,246 (  +  ) ;   84.82 min ; 930 (bp) ,   309 (aa) Go to Linear View
 Product ribokinase  
 Operon Name rbsDACBKR  
 Note GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process  
 Function enzyme; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0004747; ribokinase activity ( rbsK )
GO:0005515; protein binding ( rbsK )
GO:0005737; cytoplasm ( rbsK )
GO:0005975; carbohydrate metabolic process ( rbsK )
GO:0006014; D-ribose metabolic process ( rbsK )
GO:0016301; kinase activity ( rbsK )
GO:0016740; transferase activity ( rbsK )
 PID 1790193  
 EC number
  (KEGG Pathway)
 
2.7.1.15  
Verified Protein Starts (data compiled from literature and appropriate citations are available from EcoGene)
     EcoGene rbsK ( EG10818 )  
    Number of removed 0 aa cleaved  
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) RBSB_ECOLI ( P02925 )
    -  Protein name D-ribose-binding periplasmic protein precursor.  
    -  Synonyms  
    -  Gene name Name=rbsB; Synonyms=rbsP, prlB; OrderedLocusNames=b3751;  

 Linear View (Whole Mode)
View Location
   3925.0  –  3950.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP rbsK (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain , E. Coli Ribokinase Complexed With Ribose And Adp  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Ribokinase  
         PSI-BLAST Bifunctional protein hldE [Includes: D-beta-D-heptose 7-phosphate kinase
    nr     (database updated : 2007.02.20 )
         BLAST ribokinase [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    CYTOCHROME_C    PFKB_KINASES_1    PFKB_KINASES_2     

Other Cross-Reference
    COG COG0524G 
    EcoCyc rbsK 

MMBR References
J Biol Chem. 1986;261:7663-7668
Ribokinase from Escherichia coli K12. Nucleotide sequence and overexpression of the rbsK gene and purification of ribokinase.
Hope, J. N., A. W. Bell, M. A. Hermodson, and J. M. Groarke.
J Bacteriol. 1984;158(2):674-82.
Molecular cloning and characterization of genes required for ribose transport and utilization in Escherichia coli K-12.
Iida A, Harayama S, Iino T, Hazelbauer GL. ( 6327617 )
J Bacteriol. 1984;158(2):665-73.
D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport.
Lopilato JE, Garwin JL, Emr SD, Silhavy TJ, Beckwith JR. ( 6327616 )
ICN-UCLA Symp. Mol. Cell. Biol. 1980;19:137-159.
The origin of replication, oriC, of the Escherichia coli chromosome: genes near oriC and construction of oriC deletion mutations.
von Meyenburg, K., F. G. Hansen, E. Riise, H. E. N. Bergmans, M. Meijer, and W. Messer.

Sequences
Amino acid
FASTA format
0001 MQNAGSLVVL GSINADHILN LQSFPTPGET VTGNHYQVAF GGKGANQAVA AGRSGANIAF IACTGDDSIG 
0071 ESVRQQLATD NIDITPVSVI KGESTGVALI FVNGEGENVI GIHAGANAAL SPALVEAQRE RIANASALLM 
0141 QLESPLESVM AAAKIAHQNK TIVALNPAPA RELPDELLAL VDIITPNETE AEKLTGIRVE NDEDAAKAAQ 
0211 VLHEKGIRTV LITLGSRGVW ASVNGEGQRV PGFRVQAVDT IAAGDTFNGA LITALLEEKP LPEAIRFAHA 
0281 AAAIAVTRKG AQPSVPWREE IDAFLDRQR

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             GGTGACATAA ATACGTCATC GACAGATGAA 
-070 CGTGTAATAT AAAGAAAAGC AGGGCACGCG CCACCCTAAC ACGGTGGCGC ATTTTATGGA CATCCCGAAT 
0001 atgcaaaacg caggcagcct cgttgttctt ggcagcatta atgctgacca cattcttaat cttcaatctt 
0071 ttcctactcc aggcgaaacc gtaaccggta accactatca ggttgcattt ggcggcaaag gcgcgaatca 
0141 ggctgtggct gctgggcgta gcggtgcgaa tatcgcgttt attgcctgta cgggtgatga cagcattggt 
0211 gagagcgttc gccagcagct cgccactgat aacattgata ttactccggt cagcgtgatc aaaggcgaat 
0281 caacaggtgt ggcgctgatt tttgttaatg gcgaaggtga gaatgtcatc ggtattcatg ccggcgctaa 
0351 tgctgccctt tccccggcgc tggtggaagc gcaacgtgag cgtattgcca acgcgtcagc attattaatg 
0421 cagctggaat caccactcga aagtgtgatg gcagcggcga aaatcgccca tcaaaataag actatcgttg 
0491 cgcttaaccc ggctccggct cgcgaacttc ctgacgaact gctggcgctg gtggacatta ttacgccaaa 
0561 cgaaacggaa gcagaaaagc tcaccggtat tcgtgttgaa aatgatgaag atgcagcgaa ggcggcgcag 
0631 gtactgcatg aaaaaggtat ccgtactgta ctgattactt taggaagtcg tggtgtatgg gctagcgtga 
0701 atggtgaagg tcagcgcgtt cctggattcc gggtgcaggc tgtcgatacc attgctgccg gagatacctt 
0771 taacggtgcg ttaatcacgg cattgctgga agaaaaacca ttgccagagg cgattcgttt tgcccatgct 
0841 gccgctgcga ttgccgtaac acgtaaaggc gcacaacctt ccgtaccgtg gcgtgaagag atcgacgcat 
0911 ttttagacag gcagaggtga CGCTTGGCTA CAATGAAAGA TGTTGCCCGC CTGGCGGGCG TTTCTACCTC 
0981 AACAGTTTCT CACGTTATCA ATAAAGATCG CTTCGTCAGT GAAGCGATTA