MG1655
W3110
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Gene Report : atpE
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL01 (D)  ,  OCL01-1 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  atpE
Related strains
     Strains Search Search strains by gene name:  atpE   Search strains by all related name:  atpE b3737 ECK3730 JW3715 papH uncE

General information  (Go to Linear View:)
 Gene Name atpE  
 Alternative name b3737,ECK3730,JW3715,papH,uncE  
 Location, Length 3,918,973 - 3,919,212 (  -  ) ;   84.47 min ; 240 (bp) ,   79 (aa) Go to Linear View
 Product F0 sector of membrane-bound ATP synthase, subunit c  
 Operon Name atpIBEFHAGDC  
 Note membrane-bound ATP synthase, F0 sector, subunit c; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0015986 - ATP synthesis coupled proton transport  
 Function enzyme; ATP-proton motive force interconversion  
 Gene Ontology GO:0005886 ; plasma membrane ( atpE )
GO:0006810 ; transport ( atpE )
GO:0006811 ; ion transport ( atpE )
GO:0008289 ; lipid binding ( atpE )
GO:0015078 ; hydrogen ion transmembrane transporter activity ( atpE )
GO:0015986 ; ATP synthesis coupled proton transport ( atpE )
GO:0015992 ; proton transport ( atpE )
GO:0016020 ; membrane ( atpE )
GO:0016021 ; integral to membrane ( atpE )
GO:0016469 ; proton-transporting two-sector ATPase complex ( atpE )
GO:0016820 ; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ( atpE )
GO:0045263 ; proton-transporting ATP synthase complex, coupling factor F(o) ( atpE )
GO:0046933 ; hydrogen ion transporting ATP synthase activity, rotational mechanism ( atpE )
GO:0046961 ; hydrogen ion transporting ATPase activity, rotational mechanism ( atpE )
 PID 1790175  
 EC number
  (KEGG Pathway)
 
3.6.3.14  
Verified Protein Starts (data compiled from literature and appropriate citations are available from EcoGene)
     EcoGene atpE ( EG10102 )  
    Number of removed 0 aa cleaved  
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) ATPL_ECOLI ( P00844 )
    -  Protein name ATP synthase C chain  
    -  Synonyms EC 3.6.3.14, Lipid-binding protein, Dicyclohexylcarbodiimide-binding protein  
    -  Gene name STY3908, t3649, SF3817, S3951, YPO4126, y4140, YP4033;  

 Linear View (Whole Mode)
View Location
   3910.0  –  3935.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP atpE (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of Ala24ASP61 TO ASP24ASN61 SUBSTITUTED SUBUNIT C Of Escherichia Coli Atp Synthase  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST ATP synthase C chain (Lipid-binding protein) (Dicyclohexylcarbodiimide-binding protein)  
         PSI-BLAST ATP synthase lipid-binding protein, mitochondrial precursor
    nr     (database updated : 2007.02.20 )
         BLAST COG0636: F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K [Yersinia bercovieri ATCC 43970]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE MYRISTYL    ATPASE_C     

Other Cross-Reference
    COG COG0636C 
    EcoCyc atpE 

MMBR References
Proc Natl Acad Sci U S A. 1982;79:320-324
Gene order and gene-polypeptide relationships of the proton-translocating ATPase operon (unc) of Escherichia coli.
Gunsalus, R. P., W. S. Brusilow, and R. D. Simoni.
Biochem J. 1983;211(3):717-26.
Mutations in the uncE gene affecting assembly of the c-subunit of the adenosine triphosphatase of Escherichia coli.
Jans DA, Fimmel AL, Langman L, James LB, Downie JA, Senior AE, Ash GR, Gibson F, Cox GB. ( 6309138 )
EMBO J. 1985;4:519-526
Translational initiation frequency of atp genes from Escherichia coli: identification of an intercistronic sequence that enhances translation.
McCarthy, J. E. G., H. U. Schairer, and W. Sebald.
J Bacteriol. 1992;174:3370-3376
Effects of inducing expression of cloned genes for the F0 proton channel of the Escherichia coli F1F0 ATPase.
Monticello, R. A., E. Angov, and W. S. A. Brusilow.
Nucleic Acids Res. 1981;9:5287-5296
The atp operon: nucleotide sequence of the genes for the gamma, beta, and epsilon subunits of Escherichia coli ATP synthase.
Saraste, M., N. J. Gay, A. N. Eberle, M. J. Runswick, and J. R. Walker.
Arch Biochem Biophys. 1995;323(2):423-8.
The effects of an atpE ribosome-binding site mutation on the stoichiometry of the c subunit in the F1F0 ATPase of Escherichia coli.
Schemidt RA, Hsu DK, Deckers-Hebestreit G, Altendorf K, Brusilow WS. ( 7487107 )
Biochem J. 1984;224(3):799-815.
DNA sequence around the Escherichia coli unc operon. Completion of the sequence of a 17 kilobase segment containing asnA, oriC, unc, glmS and phoS.
Walker JE, Gay NJ, Saraste M, Eberle AN. ( 6395859 )

Sequences
Amino acid
FASTA format
0001 MENLNMDLLY MAAAVMMGLA AIGAAIGIGI LGGKFLEGAA RQPDLIPLLR TQFFIVMGLV DAIPMIAVGL 
0071 GLYVMFAVA

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             atcttcatgg ttctgacgat cgtctatctg 
-070 tcgatggcgt ctgaagaaca ttaatttacc aacactacta cgttttaact gaaacaaact ggagactgtc 
0001 atggaaaacc tgaatatgga tctgctgtac atggctgccg ctgtgatgat gggtctggcg gcaatcggtg 
0071 ctgcgatcgg tatcggcatc ctcgggggta aattcctgga aggcgcagcg cgtcaacctg atctgattcc 
0141 tctgctgcgt actcagttct ttatcgttat gggtctggtg gatgctatcc cgatgatcgc tgtaggtctg 
0211 ggtctgtacg tgatgttcgc tgtcgcgtag taagcgttgc ttttatttaa agagcaatat cagaacgtta 
0281 actaaataga ggcattgtgc tgtgaatctt aacgcaacaa tcctcggcca ggccatcgcg