MG1655
W3110
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Gene Report : bglG
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL02 (D)  ,  DE(OC3)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  bglG
Related strains
     Strains Search Search strains by gene name:  bglG   Search strains by all related name:  bglG b3723 bglC bglR bglS ECK3716 JW3701

General information  (Go to Linear View:)
 Gene Name bglG  
 Alternative name b3723,bglC,bglR,bglS,ECK3716,JW3701  
 Location, Length 3,903,754 - 3,904,590 (  -  ) ;   84.14 min ; 837 (bp) ,   278 (aa) Go to Linear View
 Product transcriptional antiterminator of the bgl operon  
 Operon Name bglGFB  
 Note positive regulation of bgl operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription  
 Function regulator; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0003723 ; RNA binding ( bglG )
GO:0006350 ; transcription ( bglG )
GO:0006355 ; regulation of transcription, DNA-dependent ( bglG )
GO:0045893 ; positive regulation of transcription, DNA-dependent ( bglG )
 PID 1790160  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) BGLG_ECOLI ( P11989 ; Q47078 )
    -  Protein name Cryptic beta-glucoside bgl operon antiterminator.  
    -  Synonyms  
    -  Gene name Name=bglG; Synonyms=bglC; OrderedLocusNames=b3723;  

 Linear View (Whole Mode)
View Location
   3895.0  –  3920.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP bglG (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of The Native And Inactive Lict Prd From B. Subtilis  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Cryptic beta-glucoside bgl operon antiterminator  
         PSI-BLAST Cryptic beta-glucoside bgl operon antiterminator
    nr     (database updated : 2007.02.20 )
         BLAST transcriptional antiterminator of the bgl operon [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    LEUCINE_ZIPPER    ANTITERMINATORS_BGLG     

Other Cross-Reference
    COG COG3711K 
    EcoCyc bglG 

MMBR References
Cell. 1990;62(6):1153-63.
Transcriptional antitermination in the bgl operon of E. coli is modulated by a specific RNA binding protein.
Houman F, Diaz-Torres MR, Wright A. ( 1698125 )
J Bacteriol. 1987;169(6):2570-8.
Positive and negative regulation of the bgl operon in Escherichia coli.
Mahadevan S, Reynolds AE, Wright A. ( 3294798 )
Nature. 1981;293(5834):625-9.
Insertion of DNA activates the cryptic bgl operon in E. coli K12.
Reynolds AE, Felton J, Wright A. ( 6270569 )
J Mol Biol. 1984;191:85-95.
Enhancement of bacterial gene expression by insertion elements or by mutation in a CAP-cAMP binding site.
Reynolds, A. E., S. Mahadevan, S. F. J. LeGrice, and A. Wright.
J Bacteriol. 1986;168(1):13-21.
Control of sensitivity to inactivation by H2O2 and broad-spectrum near-UV radiation by the Escherichia coli katF locus.
Sammartano LJ, Tuveson RW, Davenport R. ( 3019996 )
Proc Natl Acad Sci U S A. 1990;87:5074-5078
Beta-glucoside permease represses the bgl operon of Escherichia coli by phosphorylation of the antiterminator protein and also interacts with glucose-specific enzyme III, the key element in catabolite control.
Schnetz, K., and B. Rak.
Mol Microbiol. 1995;17(6):1085-92.
Transcriptional activation of the Escherichia coli bgl operon: negative regulation by DNA structural elements near the promoter.
Singh J, Mukerji M, Mahadevan S. ( 8594328 )
J Bacteriol. 1998;180:190-193
The leuO gene product has a latent ability to relieve bgl silencing in Escherichia coli.
Ueguchi, C., T. Ohta, C. Seto, T. Suzuki, and T. Mizuno.

Sequences
Amino acid
FASTA format
0001 MNMQITKILN NNVVVVIDDQ QREKVVMGRG IGFQKRAGER INSSGIEKEY ALSSHELNGR LSELLSHIPL 
0071 EVMATCDRII SLAQERLGKL QDSIYISLTD HCQFAIKRFQ QNVLLPNPLL WDIQRLYPKE FQLGEEALTI 
0141 IDKRLGVQLP KDEVGFIAMH LVSAQMSGNM EDVAGVTQLM REMLQLIKFQ FSLNYQEESL SYQRLVTHLK 
0211 FLSWRILEHA SINDSDESLQ QAVKQNYPQA WQCAERIAIF IGLQYQRKIS PAEIMFLAIN IERVRKEH

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ataaatgact ggattgttac tgcattcgca 
-070 ggcaaaacct gacataacca gagaatactg gtgaagtcgg gtttttttgt ttataaaaaa ggtccttgct 
0001 atgaacatgc aaatcaccaa aattctcaac aataatgttg tggtggttat tgatgatcaa cagcgggaaa 
0071 aagtcgtcat ggggcgcgga attggctttc aaaaacgcgc tggcgaaaga attaactcaa gtggaataga 
0141 aaaagagtat gccttgagca gtcatgaact gaacgggcga ttaagcgaac tcttaagtca tattcctctt 
0211 gaggtgatgg caacctgtga tcgtattatc tctttagcgc aggagcgctt gggaaaatta caggacagta 
0281 tttatatctc gctaactgac cattgccagt ttgcgattaa acgctttcag caaaacgtgt tgctgcccaa 
0351 cccgttgctg tgggatatcc agcggcttta cccgaaagag ttccagctag gggaagaagc gttaaccatt 
0421 attgataaac ggttgggcgt gcagttaccg aaagatgaag tgggctttat tgccatgcat ctggtcagtg 
0491 cccaaatgag cggaaatatg gaggatgttg caggtgtcac gcagttaatg cgcgaaatgc tgcaattaat 
0561 aaaatttcag ttcagcctta attaccagga agaaagcttg agttatcagc gactggttac acatctgaag 
0631 tttttatcct ggcgtattct tgaacatgct tcaattaacg atagtgatga atcattacaa caagcagtaa 
0701 aacaaaatta cccgcaagca tggcaatgtg cggaacggat cgccattttt attggtttgc agtatcaacg 
0771 taaaatttca cccgcagaga ttatgttttt agccataaat atagagcgcg tgcgcaaaga acactgaaat 
0841 attattactg agtaaaggat tgttaccgca ctaagcgggc aaaacctgaa aaaaattgct tgattcacgt 
0911 caggccgttt ttttcaggtt ttttttt