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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCL03
(D)
,
DE(OC2)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
tnaB
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Related strains
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Strains Search
|
Search strains by gene name:
tnaB
Search strains by all related name:
tnaB b3709 ECK3702 JW5619 JW5622 tnaP trpP
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General information (Go to Linear View: )
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Gene Name
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tnaB
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Alternative name
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b3709,ECK3702,JW5619,JW5622,tnaP,trpP
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Location, Length
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3,888,259 - 3,889,506
(
+
)
;
83.80
min
;
1248
(bp) ,
415
(aa)
|
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Product
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tryptophan transporter of low affinity
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Operon Name
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tnaCAB
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Note
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low affinity tryptophan permease; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0000162 - tryptophan biosynthetic process
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Function
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transport; Transport of small molecules: Amino acids, amines
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Gene Ontology
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GO:0005886
;
plasma membrane ( tnaB )
GO:0006569
;
tryptophan catabolic process ( tnaB )
GO:0006810
;
transport ( tnaB )
GO:0006865
;
amino acid transport ( tnaB )
GO:0016020
;
membrane ( tnaB )
GO:0016021
;
integral to membrane ( tnaB )
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PID
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1790145
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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TNAB_ECOLI
(
P23173
)
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- Protein name
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Low affinity tryptophan permease.
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- Synonyms
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- Gene name
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Name=tnaB; Synonyms=trpP; OrderedLocusNames=b3709;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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tnaB
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Low affinity tryptophan permease
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PSI-BLAST
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High-affinity glutamine permease
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nr
(database updated :
2007.02.20
)
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BLAST
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tryptophan transporter of low affinity [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
MYRISTYL
AMIDATION
AROMATIC_AA_PERMEASE
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MMBR References
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Biochem J. 1982;204(2):617-9.
Location of the gene for the low-affinity tryptophan-specific permease of Escherichia coli.
Edwards RM, Yudkin MD.
(
7052072
)
|
J Bacteriol. 1994;176(5):1546-7.
A copy of insertion element IS5 is present within tnaB in the Kohara library of Escherichia coli W3110.
Kamath AV, Gish K, Yanofsky C.
(
8113202
)
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J Bacteriol. 1991;173(10):3231-4.
A new family of integral membrane proteins involved in transport of aromatic amino acids in Escherichia coli.
Sarsero JP, Wookey PJ, Gollnick P, Yanofsky C, Pittard AJ.
(
2022620
)
|
J Bacteriol. 1985;164(2):731-40.
Evidence for transcription antitermination control of tryptophanase operon expression in Escherichia coli K-12.
Stewart V, Yanofsky C.
(
3902796
)
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Genomics. 1993;16(3):551-61.
DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication.
Burland V, Plunkett G 3rd, Daniels DL, Blattner FR.
(
7686882
)
|
J Bacteriol. 1981;147(3):787-96.
Nucleotide sequence of the structural gene for tryptophanase of Escherichia coli K-12.
Deeley MC, Yanofsky C.
(
6268608
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MTDQAEKKHS AFWGVMVIAG TVIGGGMFAL PVDLAGAWFF WGAFILIIAW FSMLHSGLLL LEANLNYPVG
0071 SSFNTITKDL IGNTWNIISG ITVAFVLYIL TYAYISANGA IISETISMNL GYHANPRIVG ICTAIFVASV
0141 LWLSSLAASR ITSLFLGLKI ISFVIVFGSF FFQVDYSILR DATSSTAGTS YFPYIFMALP VCLASFGFHG
0211 NIPSLIICYG KRKDKLIKSV VFGSLLALVI YLFWLYCTMG NIPRESFKAI ISSGGNVDSL VKSFLGTKQH
0281 GIIEFCLLVF SNLAVASSFF GVTLGLFDYL ADLFKIDNSH GGRFKTVLLT FLPPALLYLI FPNGFIYGIG
0351 GAGLCATIWA VIIPAVLAIK ARKKFPNQMF TVWGGNLIPA IVILFGITVI LCWFGNVFNV LPKFG
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AGAAGTTTAA TTAATACTAC AGAGTGGCTA
-070 TAAGGATGTT AGCCACTCTC TTACCCTACA TCCTCAATAA CAAAAATAGC CTTCCTCTAA AGGTGGCATC
0001 atgactgatc aagctgaaaa aaagcactct gcattttggg gtgttatggt tatagcaggt acagtaattg
0071 gtggaggtat gtttgcttta cctgttgatc ttgccggtgc ctggtttttc tggggtgcct ttatccttat
0141 cattgcctgg ttttcaatgc ttcattccgg gttattgtta ttagaagcaa atttaaatta tcccgtcggc
0211 tccagtttta acaccatcac caaagattta atcggtaaca cctggaacat tatcagcggt attaccgttg
0281 ccttcgttct ctatatcctc acttatgcct atatctctgc taatggtgcg atcattagtg aaacgatatc
0351 aatgaatttg ggttatcacg ctaatccacg tattgtcggg atctgcacag ccattttcgt tgccagcgta
0421 ttgtggttaa gttcgttagc cgccagtcgt attacctcat tgttcctcgg gctgaagatt atctcctttg
0491 tgatcgtgtt tggttctttt ttcttccagg tcgattactc cattctgcgc gacgccacca gctccactgc
0561 gggaacgtct tacttcccgt atatctttat ggctttgccg gtgtgtctgg cgtcatttgg tttccacggc
0631 aatattccca gcctgattat ttgctatgga aaacgcaaag ataagttaat caaaagcgtg gtatttggtt
0701 cgctgctggc gctggtgatt tatctcttct ggctctattg caccatgggg aatattccgc gagaaagctt
0771 taaggcgatt atctcctcag gcggcaacgt tgattcgctg gtgaaatcgt tcctcggcac caaacagcac
0841 ggcattatcg agttttgcct gctggtgttc tctaacttag ctgttgccag ttcgttcttt ggtgtcacgc
0911 tggggttgtt cgattatctg gcggacctgt ttaagattga taactcccac ggcgggcgtt tcaaaaccgt
0981 gctgttaacc ttcctgccac ctgcgttgtt gtatctgatc ttcccgaacg gctttattta cgggatcggc
1051 ggtgccgggc tgtgcgccac catctgggcg gtcattattc ccgcagtgct tgcaatcaaa gctcgcaaga
1121 agtttcccaa tcagatgttc acggtctggg gcggcaatct tattccggcg attgtcattc tctttggtat
1191 aaccgtgatt ttgtgctggt tcggcaacgt ctttaacgtg ttacctaaat ttggctaaAT CCTTCAAGAA
1261 GCCAGCCATT CGCTGGCTTC TTGCCTCTCA GGAAATCACT TATGTCCAAA TGGCAACTCG CCTGATCCTC
1331 CTTCACCACG TATGCTTT
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